Protein Alignment nesd and Shcbp1

DIOPT Version :9

• Sequence 1: NP_610025.1
• Gene: nesd / 35298
• FlyBaseID: FBgn0032848
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: XP_038951198.1
• Gene: Shcbp1 / 364648
• RGDID: 1590844
• Length: 668
• Species: Rattus norvegicus
• Alignment Length: 660
• Identity: 137/660 - (20%)
• Similarity: 253/660 - (38%)
• Gaps: 171/660 - (25%)

  Fly     5 TFEKSYLERLKEAEAVLSWEGAVMPASQVRSEWKSYVELKIEPAGWQAIW--KIPRVICEDLKLR 67
            |.|..:.||.:   |...:..|...||:|:....|::|..:||:||.|:|  .:..|:.|...:.
  Rat    73 TNELLFYERFR---AYQDYILADCKASEVKEFTVSFLEKVLEPSGWWAVWHTNVFEVLVEVTNVD 134

  Fly    68 YPTI--VYGYVEQVIFDELKAVFVVTAVQD----SDVHLPESNEVSLVELWPTVQQENAALNVDT 126
            :..:  |....|..|::...:.|.:..|::    .:.|||      |.|||......:   .|..
  Rat   135 FAALKAVVKLAEPCIYESKLSTFTLANVKELLDLKEFHLP------LQELWVVSDDSH---EVHQ 190

  Fly   127 TAECIDRLRFFYTHVWMPWDKDYDDDRDWVQQHLQARIQLVCDLSKNRLPRPLALHMRTLLAEAK 191
            .|..|:.:||||.::|..||::.:|:.|:..:.::.|::|..|:.::|:|..|.:....||::.:
  Rat   191 MALAIEHVRFFYKNIWRSWDEEEEDEYDYFVRCVEPRLRLYYDILEDRVPSGLIVDYHNLLSQCE 255

  Fly   192 YIQQRLDYLELDLSDAESDDEAVELNDSVAEPARKQSKAGSANGCLNVSSLPVTDLMCLHLRMAI 256
            ...::...|...||...||.|  :.|.|:.|.             ||           |:..:..
  Rat   256 ESYRKFLNLRSSLSSCNSDSE--QENISMVEG-------------LN-----------LYSEIEQ 294

  Fly   257 IRSEFEILENPEMRRAYSELQSNSLKRLRCSSGRTRQSEDLLVERNSISHVV--TLPGKLQQQLE 319
            ::.:.:::|||.:|..:. .|.||    ...:..|||:...::      |||  |:...|.:.|.
  Rat   295 LKQKLKLIENPLLRYVFG-YQKNS----NIQAKGTRQNGQKVI------HVVSSTMKTGLLRSLF 348

  Fly   320 LLKLAQTLVKPESKVQLSNTLQDVLSICQSNDDILLSPGEHTIKFLEHLNDNGSLRGLTQPEAIL 384
            ..:..:...|.|:::|..:.|...::.|...|.:::.||.:.:.....:.|:..|.|...|:.|
  Rat   349 RDRFCEESCKEETEIQFHSDLLSGINACYDGDTVIVCPGHYVVHGTCCIADSIELEGYGPPDDI- 412

  Fly   385 SPAADLSLLPVVCSSDEDSTLLVID----GDYTLSELVLDCRHVRRGILLRNGTLTMRGCRLLGD 445
                                  :|:    ||     ..:||..:         .:.:.|.:.:
  Rat   413 ----------------------IIEKRGKGD-----TFVDCTGM---------DVKISGVKFI-- 439

  Fly   446 GSSSTQEGIVCMPGASVELKSCLIENFAVGVSMRPKSSAEL---GSVQFKTCKTGLELLEKSASV 507
             ...:.|||:.:......|::|:::....||::|  :||||   .|..:.....|:|:
  Rat   440 -QHDSVEGILIIHHGKTTLENCVLQCETTGVTVR--TSAELFMKNSDVYGAKGAGIEI------- 494

  Fly   508 NLQGSKCS-----FENCALGILADGFVLGEQRTEKVLVLNK-----------------FSELQRY 550
             ..||||:     ..:|..|||...|:.......|:.::|.                 |.:|..:
  Rat   495 -YPGSKCTLTDNGIHHCKEGILIKDFLDEHYDIPKISMINNVIHNNEGYGVVLVKPTIFCDLLEH 558

  Fly   551 NEDNLLGNCSFYN---------------------------------CKKNVRVFNESGQLLAQRS 582
            .:|....|....|                                 .|.|..:.||...:..|:.
  Rat   559 AQDETNDNTVQKNKEADVTEGLDLEEMLQCVSNKMEPYATADFNEQAKGNCEIINELLAISMQKG 623

  Fly   583 HQQLLEDELG 592
            ..:....|||
  Rat   624 RMKKRLSELG 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nesd	NP_610025.1	None
Shcbp1	XP_038951198.1	Beta_helix	446..>546	CDD:404168	25/109 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	80	1.000	Domainoid score	I8442
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	83	1.000	Inparanoid score	I5089
OMA	1	1.010	-	-		QHG49984
OrthoDB	1	1.010	-	-		D1276823at2759
OrthoFinder	1	1.000	-	-		FOG0005693
OrthoInspector	1	1.000	-	-		oto97467
orthoMCL	1	0.900	-	-		OOG6_111415
Panther	1	1.100	-	-	LDO	PTHR14695
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6157
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.980