Protein Alignment nesd and Shcbp1l

DIOPT Version :9

• Sequence 1: NP_610025.1
• Gene: nesd / 35298
• FlyBaseID: FBgn0032848
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_001099431.1
• Gene: Shcbp1l / 289101
• RGDID: 1305609
• Length: 637
• Species: Rattus norvegicus
• Alignment Length: 636
• Identity: 133/636 - (20%)
• Similarity: 226/636 - (35%)
• Gaps: 191/636 - (30%)

  Fly    30 ASQVRSEWKS-------------------------YVELKIEPAG-WQAIWKI-PRVICEDLKLR 67
            ||.:|..|:|                         |:..|::... |..:||. |.:..|  |..
  Rat    95 ASPMRGMWRSEKVALYCDQVLQGSKAEDADEAMSKYLSEKLKVTDRWLGVWKSNPELFFE--KYE 157

  Fly    68 YPTIVY-GYVEQVIF---DELKAVFVVTAVQDSDVHLPESNEVS-------------------LV 109
            ..:|.: |.:.:|..   ..|.:.|.||.    .|..|.|:.::                   |:
  Rat   158 EASIPFVGILVEVTCKPRQNLSSCFKVTV----SVAEPFSSNIANIPRDLVDEVLGELEYSAPLL 218

  Fly   110 ELWPTVQQENAALNVDTTAECIDRLRFFYTHVWMPWDKDYDDDRDWVQQH---LQARIQLVCDLS 171
            |::|...|:   .:|...|..::.:||||..:|..|     ||.:..:.:   ::.||.|.||:.
  Rat   219 EVYPVEGQD---ADVRDIALALEVVRFFYDFLWRDW-----DDEENCENYTALIEERINLWCDIQ 275

  Fly   172 KNRLPRPLALHMRTLLAEAKYIQQRLDYLELDLSDAESDDEAVELNDSVAEPARKQSKAGSANGC 236
            ...:|.|:|...:..|  .||..:|::.:|.. |:.:.|..|.|    ..|..:|..:.....|.
  Rat   276 DGTIPGPIAQRFKKTL--EKYKNKRVELIEYQ-SNIKEDPSAAE----AVECWKKYYEIVMLCGL 333

  Fly   237 LNVSSLPVTDLMCLHLRMAIIRSEF-EILENPEMRRAYSELQSNSLKRLRCSSGRTRQSEDLLVE 300
            |.         |...||:.:....| .||...:.:|.:               |:|
  Rat   334 LK---------MWEDLRLRVHGPFFPRILRRRKGKRDF---------------GKT--------- 365

  Fly   301 RNSISHVVTLPGKLQQQLELLKLAQT-LVK---PESKVQLSNTLQDVLSICQSNDDILLSPGEHT 361
               |:|:|.            |:..| :||   .::.:|..:.|...|..|.|.|.:::.|||:.
  Rat   366 ---ITHIVA------------KVMTTDMVKNLSSDTLLQQHDDLNLALDSCYSGDIVVIFPGEYQ 415

  Fly   362 IKFLEHLNDNGSLRGLTQPEAIL---SPAAD-----------LSLLPVVCSSDEDSTLLVIDGDY 412
            ...|..|.|:.:::|:.:.|.|:   .|:.|           |..|.::.....|..::|..|..
  Rat   416 ASNLALLTDDITIKGVGKREEIMITSEPSHDSFVVSKADSVKLMQLSLIQQGTVDGIVVVESGHL 480

  Fly   413 TLSELVLDCRHVRRGILLRNGTLTMRGCRLLGDGSSSTQEGIVCMPGASVEL---KSCLIENFAV 474
            ||...:|.|          .||..   |.|.|...:.|...|....||.|||   ...::|...:
  Rat   481 TLENCLLKC----------EGTGV---CVLTGASLTITNSEITGAQGAGVELYPGSIAILEGNEI 532

  Fly   475 ----GVSMRPKSSAELGSVQFKTCKT----------------GLELLEKSASVNLQGSKCSFENC 519
                .:.....|.:.||.|..|....                |:.:|:.|.         .|...
  Rat   533 HHCNNLRTSDSSKSTLGGVNMKVLPAPKLKMTNNHIYNNNGYGVSILQPSE---------QFFIV 588

  Fly   520 ALGILADGFVLGEQRTEKVLVLNKFSELQRYNEDNLLGNCSFYNCKKNVRV 570
            |...|..|...|:::.:|:|     |::.:.....:..|....|.|.::|:
  Rat   589 AEAALNKGAASGDKKDDKML-----SKVMQTLNVEMNNNRIEANSKGDIRI 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nesd	NP_610025.1	None
Shcbp1l	NP_001099431.1	Beta_helix	470..637	CDD:289971	40/192 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	83	1.000	Inparanoid score	I5089
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1276823at2759
OrthoFinder	1	1.000	-	-		FOG0005693
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14695
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	7.030