Protein Alignment Pyroxd1 and AIFM2

DIOPT Version :9

• Sequence 1: NP_001260619.1
• Gene: Pyroxd1 / 35296
• FlyBaseID: FBgn0032846
• Length: 472
• Species: Drosophila melanogaster
• Sequence 2: NP_001185625.1
• Gene: AIFM2 / 84883
• HGNCID: 21411
• Length: 373
• Species: Homo sapiens
• Alignment Length: 451
• Identity: 85/451 - (18%)
• Similarity: 165/451 - (36%)
• Gaps: 148/451 - (32%)

  Fly     8 LVVGGGIAGVSCAESLAIYRPNASILLLTESSIVKSVTNLVPVARYLHKFDVRE---QDVSEMGA 69
            ::||||..|::.|..|...  |...:|:                      |:::   .:|:.:.|
Human    15 VIVGGGFGGIAAASQLQAL--NVPFMLV----------------------DMKDSFHHNVAALRA 55

  Fly    70 SFQT----------LVDRLDH--------INSREHCIRTKAGLEIKYRYLCLCTGGTPKLFSGKV 116
            |.:|          .|...|:        |:.:...:..:.|..:.:.:|.|.||.|.. |.||.
Human    56 SVETGFAKKTFISYSVTFKDNFRQGLVVGIDLKNQMVLLQGGEALPFSHLILATGSTGP-FPGKF 119

  Fly   117 --VNPLVIGIRD-TDSVQLLQRKLATAKDVLILGNGGIASELAYELKDVNVHWVVKDSHISATFV 178
              |:.....|:. .|.|:.:||    ::.::::|.|....|:|.|:|.......|...|......
Human   120 NEVSSQQAAIQAYEDMVRQVQR----SRFIVVVGGGSAGVEMAAEIKTEYPEKEVTLIHSQVALA 180

  Fly   179 DPGAAEFFHIAMNECNAKDSSPVVAIKRMRYSEVLPKEQTNNHGAALGPDWHRSVDLSGAREGEE 243
            |                |:..|.|   |....|:|                        .|:|.:
Human   181 D----------------KELLPSV---RQEVKEIL------------------------LRKGVQ 202

  Fly   244 NRLPKIYYKSRISSVQDL-ADDAGAIVKLEHEDGSFQQLTCDFIVSATGVWPNTD-YTCDSPLQF 306
                 :....|:|::::| .::....:|::.:.|:  ::..:.::..||:..|:. |......:.
Human   203 -----LLLSERVSNLEELPLNEYREYIKVQTDKGT--EVATNLVILCTGIKINSSAYRKAFESRL 260

  Fly   307 SDDGGISVDEMMRT-NLVDVFAAGDVCTANWPAAMHWFQMRLWTQARQMGSMAG--RSMAAASEG 368
            :..|.:.|:|.::. ...:|:|.||......|               :|..:||  .::|.|:..
Human   261 ASSGALRVNEHLQVEGHSNVYAIGDCADVRTP---------------KMAYLAGLHANIAVANIV 310

  Fly   369 ESVYQDFCFELFGHVTKLFGY-PVVL-----------LGRFNGQDLGRDYEILVRCTRNKE 417
            .||.|          ..|..| |..|           :|:.:|..:||   ::||.|::::
Human   311 NSVKQ----------RPLQAYKPGALTFLLSMGRNDGVGQISGFYVGR---LMVRLTKSRD 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pyroxd1	NP_001260619.1	Pyr_redox_2	8..355	CDD:285266	66/373 (18%)
AIFM2	NP_001185625.1	NirB	39..356	CDD:330997	77/421 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0446
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1463391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910