DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pyroxd1 and CG10700

DIOPT Version :9

Sequence 1:	NP_001260619.1	Gene:	Pyroxd1 / 35296	FlyBaseID:	FBgn0032846	Length:	472	Species:	Drosophila melanogaster
Sequence 2:	NP_609942.1	Gene:	CG10700 / 35183	FlyBaseID:	FBgn0032754	Length:	539	Species:	Drosophila melanogaster

Alignment Length:	431	Identity:	94/431 - (21%)
Similarity:	170/431 - (39%)	Gaps:	95/431 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 FLVVGGGIAGVSCAESLAIYRPNASILLLT-ESSIVKSVTNLVPVAR-YLHKFDVR-EQDVSEMG 68
            |:|||||.:|..|.|:|........:.|:. |..:....|.::.:.. |.....:| ||...:.|
  Fly   134 FVVVGGGPSGAVCVETLRQEGFTGRLTLVCGEKHLPYDRTRIMNLLNTYTKNLALREEQFYKDYG 198

  Fly    69 ASFQTLV--DRLDHINSREHCIRTKAGLEIKYRYLCLCTGGTPKLFSGKVVNPLVIGIRDTDSVQ 131
            ...|..|  :|||...:..||..   |....|..:.:.||.:       .|.|.:.|:.
  Fly   199 IEMQLGVSAERLDTNCNTLHCTN---GKTFPYDKIYIATGYS-------AVTPNIPGVH------ 247

  Fly   132 LLQRKLATAKDVLILGNGGIASELAYELKDVNVHWVVKDSHISATFVDPGAAEFFHIAMNECNAK 196
                    .|:|.::.|.|.|..: :::.|.:...|...|...|.          ....|..:..
  Fly   248 --------LKNVKVIRNIGDARSI-FKMVDKSTQVVCLGSSFMAV----------EATANLVSRA 293

  Fly   197 DSSPVVAIKRMRYSEVLPKEQTNNHGAALGPDWHRSVDLSGAREGEENRLPKIYYKSRISS--VQ 259
            .|..:||.:.:.:...|        |..:|   .|.:.|.     |||::     ..|:||  ::
  Fly   294 RSVTLVARQNVPFKSTL--------GELIG---QRILKLL-----EENKV-----DLRMSSGIIR 337

  Fly   260 DLADDAGAIVKLEHEDGSFQQLTCDFIVSATGVWPNTDYTCDSPLQFSDDGGISVDEMMRTNLVD 324
            .|.:..|.:|.::..|.|  ::.|:.::..||...|||:...|.:..:.:|.:.|::.::|.:.:
  Fly   338 ILGNSRGEVVAVKLLDNS--RIPCNLLILGTGCQCNTDFLQRSGININPNGSVDVNDFLQTKVRN 400

  Fly   325 VFAAGDVCTA----NWPAAMHWFQMRLWTQARQMGSMAGRSMAAASEGESVYQDFCFELFGHVTK 385
            |:..||:..|    .:|..::.....|   |:..|.:|..:|:                 ||:.|
  Fly   401 VYVGGDIANAYILGGFPDRVNISHYGL---AQYHGRIAALNMS-----------------GHIAK 445

  Fly   386 LFGYP---VVLLGR-FNGQDLGRDYEILVRCTRNKEYIKFV 422
            |...|   .|:.|| |.....|...::::  ..:.|.::||
  Fly   446 LEAIPFFYTVIFGRAFRSAGYGPFKDVVI--DGSLEDLQFV 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pyroxd1	NP_001260619.1	Pyr_redox_2	8..355	CDD:285266	77/357 (22%)
CG10700	NP_609942.1	Rieske_AIFL_N	10..106	CDD:239560
		Pyr_redox_2	135..414	CDD:285266	74/336 (22%)
		Pyr_redox	273..350	CDD:278498	21/107 (20%)
		COG3393	336..>508	CDD:225928	38/173 (22%)
		Reductase_C	464..527	CDD:291425	4/23 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464304
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0446
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740