DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pyroxd1 and pyroxd1

DIOPT Version :9

Sequence 1:	NP_001260619.1	Gene:	Pyroxd1 / 35296	FlyBaseID:	FBgn0032846	Length:	472	Species:	Drosophila melanogaster
Sequence 2:	NP_001120558.1	Gene:	pyroxd1 / 100145712	XenbaseID:	XB-GENE-5873721	Length:	494	Species:	Xenopus tropicalis

Alignment Length:	500	Identity:	211/500 - (42%)
Similarity:	302/500 - (60%)	Gaps:	51/500 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 EFLVVGGGIAGVSCAESLAIYRPNASILLLTESSIVKSVTNLVPVARYLHKFDVREQDVSEMGAS 70
            :|:|||||||||:|||.||...|:..:.|||.|.::|:.|||..|:|.|..|||.||:.:.:...
Frog    13 KFVVVGGGIAGVTCAEELAAQFPSDRVYLLTASPLIKATTNLKQVSRTLEAFDVEEQEGTALEGR 77

  Fly    71 F---QTLVDRLDHINSREHCIRTKAGLEIKYRYLCLCTGGTPKLFSGKVVNPLVIGIRDTDSVQL 132
            :   ..:...:..:.|:|..:.|:.|...:|..||||.|...|:.:|.  ||.|:|||||||.:.
Frog    78 YPNISVVQSAVRELRSQEQEVVTEDGARYRYNKLCLCAGAKAKIIAGG--NPYVLGIRDTDSARE 140

  Fly   133 LQRKLATAKDVLILGNGGIASELAYELKDVNVHWVVKDSHISATFVDPGAAEFFHIAMNECNAKD 197
            .||.|::|:.|:|:||||||.||.|||:.....|.::|..|..||.|.|||:|.   :.:..|..
Frog   141 FQRHLSSARRVVIVGNGGIALELVYELEGCQAIWAIRDGAIGNTFFDAGAAQFL---LPQLGADK 202

  Fly   198 SSPVVAIKRMRYSEVLPKEQTNNH-GAALGPDWHRSVDL--SGAREGEENRLPKIYYKSRISSVQ 259
            ....:..:|.:|:...|....... |:|||||||..::|  :||            :..|: .::
Frog   203 PPAPLPCRRTKYTTEPPLGGGGGSVGSALGPDWHEGLNLKATGA------------FSHRV-HIE 254

  Fly   260 DLADDAGAIVKLEHE-------------DGS-------FQQLT------CDFIVSATGVWPNTD- 297
            ...:....:::.|.|             |.:       :.|||      ||||||||||.||.:
Frog   255 AQCEVRRILLREEREGLNITALPFPGESDSAPSTDWPVYVQLTNGKTYGCDFIVSATGVVPNIEP 319

  Fly   298 YTCDSPLQFSDDGGISVDEMMRTNLVDVFAAGDVCTANWPAAMHWFQMRLWTQARQMGSMAGRSM 362
            :...:....::|||:.|::.|.|::.:::||||:|||:|..:..|.||||||||||||..||:.|
Frog   320 FVTGNQFDVAEDGGLRVNDHMETSVRNIYAAGDICTASWEPSALWQQMRLWTQARQMGWYAGKCM 384

  Fly   363 AAASEGESVYQDFCFELFGHVTKLFGYPVVLLGRFNGQDLGRDYEILVRCTRNKEYIKFVLQNGR 427
            ||....:.:..|||||||.||||.|.|.|:|||::|.|.||.|:|:|:|||:.:||:|.||:.||
Frog   385 AADFLQQPIEMDFCFELFAHVTKFFNYKVILLGKYNAQGLGSDHELLLRCTKGREYVKAVLRGGR 449

  Fly   428 LRGAMLIGNTDLAETCENLILNGIDLEPYGDDILNPDIDIEDYFD 472
            :.||:|||:|||.||.|||:||.:||.|||:.:|:||:|||||||
Frog   450 MVGAVLIGDTDLEETFENLMLNQMDLSPYGERLLDPDVDIEDYFD 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pyroxd1	NP_001260619.1	Pyr_redox_2	8..355	CDD:285266	139/379 (37%)
pyroxd1	NP_001120558.1	Pyr_redox_2	<97..377	CDD:423044	106/297 (36%)
pyroxd1	NP_001120558.1	NirB	<294..>485	CDD:224171	102/190 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	129	1.000	Domainoid score	I5209
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H11758
Inparanoid	1	1.050	378	1.000	Inparanoid score	I2027
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1463391at2759
OrthoFinder	1	1.000	-	-		FOG0006989
OrthoInspector	1	1.000	-	-		oto105470
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1984
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060