DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10747 and plcxd2

DIOPT Version :9

Sequence 1:	NP_001260618.1	Gene:	CG10747 / 35295	FlyBaseID:	FBgn0032845	Length:	328	Species:	Drosophila melanogaster
Sequence 2:	XP_688423.2	Gene:	plcxd2 / 559936	ZFINID:	ZDB-GENE-091204-217	Length:	320	Species:	Danio rerio

Alignment Length:	321	Identity:	106/321 - (33%)
Similarity:	165/321 - (51%)	Gaps:	30/321 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SKDHWMRDLPSELRDLSIINLAIPGSHNSMTYGINSKSELSPDAEISIRRWHRFFPCF----VRR 62
            |...||..|...|..:.:.:||:||||:|.::.::.::.:.||.:..::.....|...    :::
Zfish    10 SNADWMGSLCPALTSMPLKHLAVPGSHDSFSFWVDEQAPVGPDQKAYVKHLAAIFRFLAKKVMKK 74

  Fly    63 WSKTQSSGTLDQLELGVRYFDLRIAQK----DDKFYYCHGLFAMEIFEPLLEIRQFVDTHPEEVV 123
            ||.||:....:|||.|:||||||::.|    ..:.|:.||||..::.:.|.:|..|::.|.:|||
Zfish    75 WSMTQNLTFREQLEGGIRYFDLRVSSKPGEAGHEIYFIHGLFGHKVRDGLNDINNFLNIHKKEVV 139

  Fly   124 ILDLQHFYAMTVAHHQKLHKDLIQFFAHRLYSTVDGSLKDCTLNRCLEMQRSVVIIYRR-----C 183
            .||..|.|||...||:.|.|.|...|.|:| ..:| .:::.|||...|.:..|::.|..     |
Zfish   140 FLDFNHHYAMGEEHHRYLIKMLQDVFGHKL-CRID-VVEEITLNYLWENRYQVLVFYHHPSAEGC 202

  Fly   184 PIPLPLRFWPSYAWPTPWPNKASVKKLQSFLEDSLLSRQPQQGY-VSQCLITPTGRYIAFRLFFT 247
            |:     .||....|.||.|.....||..|||.:|..|.....: |||.::||..:.||..|...
Zfish   203 PV-----MWPGSKIPAPWANTTDTTKLIQFLETTLGERAKYGSFHVSQAILTPRVKTIARGLVQG 262

  Fly   248 LKS-TAKRVDKKLQPWIQEQIPGPFEPKDEPRVNVFLADFVSLKGGQFCDWVVDLNTKLLE 307
            |:: ..:|....:..|::.|.||    ||  .||:..:|||.|.  .|.:.|:.|||.|::
Zfish   263 LRNYLVERNLPTIMTWVEAQKPG----KD--GVNIITSDFVELV--DFANTVIKLNTLLIK 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10747	NP_001260618.1	PI-PLCXD1c	10..302	CDD:176555	99/306 (32%)
plcxd2	XP_688423.2	PI-PLCXD1c	18..310	CDD:176555	99/306 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594162
Domainoid	1	1.000	134	1.000	Domainoid score	I4959
eggNOG	1	0.900	-	-		E1_KOG4306
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H44374
Inparanoid	1	1.050	165	1.000	Inparanoid score	I4162
OMA	1	1.010	-	-		QHG48428
OrthoDB	1	1.010	-	-		D477702at2759
OrthoFinder	1	1.000	-	-		FOG0001362
OrthoInspector	1	1.000	-	-		otm24947
orthoMCL	1	0.900	-	-		OOG6_104132
Panther	1	1.100	-	-	LDO	PTHR13593
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3805
SonicParanoid	1	1.000	-	-		X855
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800