Protein Alignment CG10747 and PLCXD1

DIOPT Version :10

• Sequence 1: NP_610022.3
• Gene: CG10747 / 35295
• FlyBaseID: FBgn0032845
• Length: 328
• Species: Drosophila melanogaster
• Sequence 2: NP_060860.1
• Gene: PLCXD1 / 55344
• HGNCID: 23148
• Length: 323
• Species: Homo sapiens
• Alignment Length: 328
• Identity: 90/328 - (27%)
• Similarity: 149/328 - (45%)
• Gaps: 48/328 - (14%)

  Fly     2 SKDHWMRDLPSELRDLSIINLAIPGSHNSMTYGINSKSELSPDAEISIRRWHRFFPCFVR----R 62
            :.:.||..|...|.|:.:.:|:|||||::|||.:|.||.:|.:....::..::..||..|    :
Human    19 ANEDWMSALCPRLWDVPLHHLSIPGSHDTMTYCLNKKSPISHEESRLLQLLNKALPCITRPVVLK 83

  Fly    63 WSKTQSSGTLDQLELGVRYFDLRIAQ----KDDKFYYCHGLFAMEIFE-PLLEIRQFVDTHPEEV 122
            ||.||:....:||:.||||.|||||.    .:...::.|.::...:.| .|.||.::::.||.||
Human    84 WSVTQALDVTEQLDAGVRYLDLRIAHMLEGSEKNLHFVHMVYTTALVEDTLTEISEWLERHPREV 148

  Fly   123 VILDLQHFYAMTVAHHQKLHKDLIQFFAHRLYSTVDGSLKDC------TLNRCLEMQRSVVIIYR 181
            |||..::|..::...|:.|...:...|...|          |      ||.:.....:.|::.|.
Human   149 VILACRNFEGLSEDLHEYLVACIKNIFGDML----------CPRGEVPTLRQLWSRGQQVIVSYE 203

  Fly   182 -RCPIPLPLRFWPSYAWPTPWPNKASVKKLQSFLEDSLLSRQPQQGYVSQCLITPTGRYIAFRLF 245
             ...:......||..  |..|.|:...:.|..:||......:|...:|:...:|...:|:
Human   204 DESSLRRHHELWPGV--PYWWGNRVKTEALIRYLETMKSCGRPGGLFVAGINLTENLQYV----- 261

  Fly   246 FTLKSTAKRVDK-------KLQPWIQEQIPGPFEPKDEPRVNVFLADFVSLKGGQFCDWVVDLNT 303
              |...::.::|       :|..|::||.|||    .....|:...||:...|  |...|:.||.
Human   262 --LAHPSESLEKMTLPNLPRLSAWVREQCPGP----GSRCTNIIAGDFIGADG--FVSDVIALNQ 318

  Fly   304 KLL 306
            |||
Human   319 KLL 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10747	NP_610022.3	PI-PLCXD1c	10..302	CDD:176555	83/314 (26%)
PLCXD1	NP_060860.1	PI-PLCXD1c	27..317	CDD:176555	83/314 (26%)