DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10747 and PLCXD2

DIOPT Version :9

Sequence 1:	NP_001260618.1	Gene:	CG10747 / 35295	FlyBaseID:	FBgn0032845	Length:	328	Species:	Drosophila melanogaster
Sequence 2:	NP_001172035.1	Gene:	PLCXD2 / 257068	HGNCID:	26462	Length:	305	Species:	Homo sapiens

Alignment Length:	254	Identity:	99/254 - (38%)
Similarity:	144/254 - (56%)	Gaps:	11/254 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 WMRDLPSELRDLSIINLAIPGSHNSMTYGINSKSELSPDAEISIRRWHR--FFPCFVRRWSKTQS 68
            ||..||..|.:|.:.||||||||:|.:|.::.||.:.||...:|:|..|  .....:::||.||:
Human    35 WMASLPPHLHNLPLSNLAIPGSHDSFSYWVDEKSPVGPDQTQAIKRLARISLVKKLMKKWSVTQN 99

  Fly    69 SGTLDQLELGVRYFDLRIAQK----DDKFYYCHGLFAMEIFEPLLEIRQFVDTHPEEVVILDLQH 129
            ....:|||.|:||||||::.|    |.:.|:.||||.:::::.|:||..|:..||:|::.||..|
Human   100 LTFREQLEAGIRYFDLRVSSKPGDADQEIYFIHGLFGIKVWDGLMEIDSFLTQHPQEIIFLDFNH 164

  Fly   130 FYAMTVAHHQKLHKDLIQFFAHRLYSTVDGSLKDCTLNRCLEMQRSVVIIYRRCPIPLPLRF-WP 193
            ||||...||:.|...:.:.|.::|....  |::..||....|....|:|.| .||......| ||
Human   165 FYAMDETHHKCLVLRIQEAFGNKLCPAC--SVESLTLRTLWEKNCQVLIFY-HCPFYKQYPFLWP 226

  Fly   194 SYAWPTPWPNKASVKKLQSFLEDSLLSRQPQQGY-VSQCLITPTGRYIAFRLFFTLKST 251
            ....|.||.|..||:||..|||.:|..|..:..: |||.::||..:.||..|...||:|
Human   227 GKKIPAPWANTTSVRKLILFLETTLSERASRGSFHVSQAILTPRVKTIARGLVGGLKNT 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10747	NP_001260618.1	PI-PLCXD1c	10..302	CDD:176555	97/250 (39%)
PLCXD2	NP_001172035.1	PI-PLCXD1c	39..291	CDD:176555	97/250 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158252
Domainoid	1	1.000	134	1.000	Domainoid score	I5026
eggNOG	1	0.900	-	-		E1_KOG4306
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H44374
Inparanoid	1	1.050	171	1.000	Inparanoid score	I4107
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48428
OrthoDB	1	1.010	-	-		D477702at2759
OrthoFinder	1	1.000	-	-		FOG0001362
OrthoInspector	1	1.000	-	-		otm40808
orthoMCL	1	0.900	-	-		OOG6_104132
Panther	1	1.100	-	-	LDO	PTHR13593
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3805
SonicParanoid	1	1.000	-	-		X855
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800