Protein Alignment neb and ARK3

DIOPT Version :10

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: NP_001184972.1
• Gene: ARK3 / 837799
• AraportID: AT1G12430
• Length: 920
• Species: Arabidopsis thaliana
• Alignment Length: 1132
• Identity: 271/1132 - (23%)
• Similarity: 440/1132 - (38%)
• Gaps: 314/1132 - (27%)

  Fly    79 YRNANS-----TPGRAKTPGTGKSSCSRTKE--RDSLMESCLSVSEES----------NMIVAVR 126
            |||...     |...|.|...|:.:..::|.  |.|...:....|.:|          .:.||||
plant    12 YRNGTQRSSLRTQSSASTSSGGQKASVKSKSVLRKSSPAALGGGSSKSGGGGDAGVPGRVRVAVR 76

  Fly   127 VRPLNALE-CTRGQVTNVVQVHGNSNELTVQAGSSADASAGVTHFFSYDQVYYSCDPERKNFACQ 190
            :||.|..| .......:.|::......|.::..:      ..|..|.:|:|.       ..:|.|
plant    77 LRPRNGEELIADADFADCVELQPELKRLKLRKNN------WDTDTFEFDEVL-------TEYASQ 128

  Fly   191 AKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSM--MGIEALDDAALDGGPPHDEAGIIPRF 253
            .:|:|..|:|:::...:|||..:.||||||:||:|::  :|.|.:.|..:
plant   129 KRVYEVVAKPVVEGVLDGYNGTIMAYGQTGTGKTYTLGQLGEEDVADRGI--------------- 178

  Fly   254 CHELFRRIEAVKSQQQLQVE-VEVSYFEIYNEKIHDLLSVQHAAAATGESTPIQQQQQQQRPALK 317
               :.|.:|.:.::..|:.: :.|||.::|.|.:.|||...:...|..|..             |
plant   179 ---MVRAMEDILAEVSLETDSISVSYLQLYMETVQDLLDPSNDNIAIVEDP-------------K 227

  Fly   318 VREHPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHSIFNIVLNL-TDLS 381
            ..:..:.|..:|::.    |..|.| ..|.:|.:.|..|:|.:|.:|||||:|  :::|: ..:.
plant   228 NGDVSLPGATLVEIR----DQQSFL-ELLQLGEAHRFAANTKLNTESSRSHAI--LMVNVRRSMK 285

  Fly   382 SDDGLSSDT--DSSTASSLRQ--TRRSKISLVDLAGSERISVSGSNGERIREGVSINKSLLTLGK 442
            :.|||||::  :|....||:.  .|:.|:.:|||||||||:.|||.|..:.|..|||.||..|||
plant   286 TRDGLSSESNGNSHMTKSLKPPVVRKGKLVVVDLAGSERINKSGSEGHTLEEAKSINLSLSALGK 350

  Fly   443 VIAALADSRKAIANGPLGSGTPSTFVPYRESVLTWLLRENLGGNSKTVMLATISPASIHADETLA 507
            .|.|||::              |:.||:|:|.||.|||::.||.::|.::.||.|:..|..||.:
plant   351 CINALAEN--------------SSHVPFRDSKLTRLLRDSFGGTARTSLVITIGPSPRHRGETTS 401

  Fly   508 TLRYACKARSIVNRVKVNES-PHDKIIRDLRAEVDRLKSLRNEYERQRRLSGNSNNPVPRKIIIE 571
            |:.:..:|..:.|.||:.|. .:..:.|.|..::|   :|..|.|||::
plant   402 TIMFGQRAMKVENMVKIKEEFDYKSLSRRLEVQLD---NLIEENERQQK---------------- 447

  Fly   572 TSVDETE---VEALRQQLAERER--------ELSRAQKSWMEKLKEAEDQRKSELRVLKRRGLA- 624
            ..|||.|   ||| ..|::|.|:        |..|.|..:||.:|:.|:......:.|....||
plant   448 AFVDEIERITVEA-HNQISEAEKRYANALEDEKLRYQNDYMESIKKLEENWSKNQKKLAAERLAL 511

  Fly   625 -----LELTAEQKQACLVNLTADPILS--GTLFYLLPQGLVRIGRGRLPGGSSSSQPDIVLDGPL 682
                 |::|:..      |.:..|.|.  ..|..||               ...:|..:..:..:
plant   512 GEKNGLDITSNG------NRSIAPALEEVSELKKLL---------------QKEAQSKMAAEEEV 555

  Fly   683 VALQHCSIEHERGGKLYVIPGSEDFETYVNGELLKDRRQLFHGDRLVIGGSHYFRISNPFCSQRG 747
            ..|:|...|.::            .|...|.|:::..:.|.:..:                 |:.
plant   556 NRLKHQLNEFKK------------VEASGNSEIMRLHKMLENETQ-----------------QKE 591

  Fly   748 KADHPVDFQLAHQEILQKQEQQLRSELEA-EKRAALTKIEQERAQHARDFEERLQCLELEQFKYK 811
            |.:         .||.....|.|:..|.| |.|..|.:...|:...|||  ..:..|.|.|.:..
plant   592 KLE---------GEIATLHSQLLQLSLTADETRRNLEQHGSEKTSGARD--SLMSQLRLPQIQDP 645

  Fly   812 CNSEMLETERQALALAQQQEHTPLRHEDA-------------VSTPAQKSTILE-----DIQRIM 858
            .|:|.....|....:..|:..:.|..|||             .:..|.:..|:|     .:..::
plant   646 GNAEKPPVARLFEQVGLQKILSLLEAEDADVRIHAVKVVANLAAEEANQQQIVEAGGLTSLLMLL 710

  Fly   859 LNPSEESLHK------TQLMVKEATQRCRQLDLPLEFRQTQTPDEFGLLRTVILILDKQRGLKAE 917
            .|..:|::|:      ..|.:.|..|.                          ||:| |.|:...
plant   711 KNTEDETIHRVAAGAIANLAMNETNQE--------------------------LIMD-QGGIGLL 748

  Fly   918 WPTARLGVWLDLVRDNAEQQEKLN--ATTIFQSVEVDWEPLDADL--NETL-SDTHNSSRIALNL 977
            ..||.          |||..:.|.  |..|            |:|  |:.| :...:...||..|
plant   749 SSTAA----------NAEDPQTLRMVAGAI------------ANLCGNDKLQTKLRSEGGIAALL 791

  Fly   978 SAMK----DVLLNKPLKRLLNASSSKSNTPRQTSTPSPGSQLVHFTKRLLTYDPEEIPESQSSFT 1038
            ..::    |||. :..:.:.|.:..:|....|..|....|.|:                ...:.:
plant   792 GMVRCGHPDVLA-QVARGIANFAKCESRASTQAGTKRGKSLLI----------------EDGALS 839

  Fly  1039 TLVQQELQIMQRSAQRLRRHCEAALLERENHQDN-------GVL--AVSLQEALARMDTVLNGMH 1094
            .:||.    .:.....:|||.|.||.....|:.|       |.:  .|.:....:|.|.
plant   840 WIVQN----AKTETAAIRRHIELALCHLAQHEGNAKEMVKEGAMWELVRISRDCSREDI------ 894

  Fly  1095 TSLARAEATACVTSPTKTQKAVRFLID 1121
            .|||....|   :|||...:..|..:|
plant   895 RSLAHRTLT---SSPTFLTELRRLRVD 918

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	128/424 (30%)
		SMC_N	514..>615	CDD:481474	30/112 (27%)
		FHA_KIF14	627..741	CDD:438759	15/115 (13%)
ARK3	NP_001184972.1	Kinesin	76..412	CDD:459720	121/400 (30%)
		EnvC	425..>620	CDD:443969	55/273 (20%)
		armadillo repeat	656..687	CDD:293788	5/30 (17%)
		Arm	693..731	CDD:425727	6/37 (16%)
		armadillo repeat	696..729	CDD:293788	5/32 (16%)
		Syo1_like	697..>883	CDD:474028	48/255 (19%)
		armadillo repeat	736..773	CDD:293788	16/85 (19%)
		armadillo repeat	779..811	CDD:293788	6/32 (19%)