Protein Alignment neb and FRA1

DIOPT Version :10

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: NP_199593.2
• Gene: FRA1 / 834833
• AraportID: AT5G47820
• Length: 1035
• Species: Arabidopsis thaliana
• Alignment Length: 986
• Identity: 273/986 - (27%)
• Similarity: 424/986 - (43%)
• Gaps: 268/986 - (27%)

  Fly   117 EESNMIVAVRVRPLNALECTRGQVTNVVQVHGNSNELTVQAGSSADASAGVTHFFSYDQVYYSCD 181
            ::.::.|||.:|||...|..:|....|..|.|...   ||.||         |.|::|.||.|
plant     8 DDCSVKVAVHIRPLIGDERIQGCQDCVTVVTGKPQ---VQIGS---------HSFTFDHVYGS-- 58

  Fly   182 PERKNFACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMGIEALDDAALDGGPPHDE 246
                :.:...:::|..|.||:|..|:||||.:.|||||||||:|: ||....|.:         :
plant    59 ----SGSPSTEMYEECAAPLVDGLFQGYNATVLAYGQTGSGKTYT-MGTGCGDSS---------Q 109

  Fly   247 AGIIPRFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEKIHDLLS--------------VQHAAA 297
            .||||:..:.||.:||.:|  ||::.::.||:.||:.|::.|||.              |...|.
plant   110 TGIIPQVMNALFTKIETLK--QQIEFQIHVSFIEIHKEEVQDLLDPCTVNKSDTNNTGHVGKVAH 172

  Fly   298 ATGESTPIQQQQQQQRPALKVREHPIFGPYVVDLSAHSVDSYSALRNWLAV---GNSQRATASTA 359
            ..|            :|.:::||   ....|:.|:..:..|.|.|:...|.   |:..|||.||.
plant   173 VPG------------KPPIQIRE---TSNGVITLAGSTEVSVSTLKEMAACLDQGSVSRATGSTN 222

  Fly   360 MNDKSSRSHSIFNI-VLNLTDLSSDDGLSSDTDSSTASSLRQTRRSKISLVDLAGSERISVSGSN 423
            ||::|||||:||.| |..:..:::|   |.:..:...|...:...:|:.|||||||||...:||:
plant   223 MNNQSSRSHAIFTITVEQMRKINTD---SPENGAYNGSLKEEYLCAKLHLVDLAGSERAKRTGSD 284

  Fly   424 GERIREGVSINKSLLTLGKVIAALADSRKAIANGPLGSGTPSTFVPYRESVLTWLLRENLGGNSK 488
            |.|.:|||.|||.||.||.||:||.|.:|.         .....||||:|.||.||:::|||||:
plant   285 GLRFKEGVHINKGLLALGNVISALGDEKKR---------KDGAHVPYRDSKLTRLLQDSLGGNSR 340

  Fly   489 TVMLATISPASIHADETLATLRYACKARSIVNRVKVNESPHDKIIRDLRAEVDRLKSLRNEYERQ 553
            |||:|.||||.|:|:|||.||:||.:||:|.|:..||..|....:..:|.:|:.|::     |..
plant   341 TVMIACISPADINAEETLNTLKYANRARNIRNKPVVNRDPVSSEMLKMRQQVEYLQA-----ELS 400

  Fly   554 RRLSGNSNNPVPRKIIIETSVDETEVEALRQQLAERERELSRAQKSWMEKLKEAEDQRKSELRVL 618
            .|..|:|.               .||:||::::.            |:|   .|.::...||...
plant   401 LRTGGSSC---------------AEVQALKERIV------------WLE---TANEELCRELHEY 435

  Fly   619 KRR--GLALELTAEQKQACLVNLTADPILSGTLFYLLPQGLVRIGRGRLPGGSSSSQPDIVL--- 678
            :.|  |:      |..:....::.||.|:..    :.|.||.|    .|....||:.|.:..
plant   436 RSRCPGV------EHSEKDFKDIRADDIVGS----VRPDGLKR----SLHSIESSNYPMVEATTG 486

  Fly   679 DGPLVALQHCSIEHERGGKLYVIPGSEDFETYVNGELLKDRR---QLFHGDRLVIGGSHYFRISN 740
            |...:..:....||:      ::..|.|.|.|.....|:::.   :||.|........|:
plant   487 DSREIDEEAKEWEHK------LLQNSMDKELYELNRRLEEKESEMKLFDGYDPAALKQHF----- 540

  Fly   741 PFCSQRGKADHPVDFQLAHQEILQKQEQQLRSELEAE-----KRAALTKIEQERAQHARDFEERL 800
                  ||       ::|..|..::..|:.|:.|.||     ......|::...||:.:..|.::
plant   541 ------GK-------KIAEVEDEKRSVQEERNRLLAEIENLASDGQAQKLQDVHAQNLKALEAQI 592

  Fly   801 QCLELEQFKYKCNSEMLETERQALALAQQQEHTPLRHEDAV-STPAQKSTILEDIQRIMLNPSEE 864
            ..|:.:|          |::.|.|...|:.:....|.:|.: |..|||         :.|.
plant   593 LDLKKKQ----------ESQVQLLKQKQKSDDAARRLQDEIQSIKAQK---------VQLQ---- 634

  Fly   865 SLHKTQLMVKEATQRCRQLDLPLEFRQTQTPDEFGLLRTVILILDKQRGLKAEWPTARLGVWLDL 929
              |:   |.:||.|          |||.:...|..||:.      ::.|.|:|:
plant   635 --HR---MKQEAEQ----------FRQWKASREKELLQL------RKEGRKSEY----------- 667

  Fly   930 VRDNAEQQEKLNATTIFQSVEVDWEPLDADLNETLSDTHNSSRIALNLSAMKDVLLNKPLKRLLN 994
                  ::.||.|                 ||:       ..::.|.....:..:..|.||.||.
plant   668 ------ERHKLQA-----------------LNQ-------RQKMVLQRKTEEAAMATKRLKELLE 702

  Fly   995 ASSSKSNTPRQTSTPSPGSQLVHFTKRLLTYDPEEIPESQSSFTTLVQQELQIM-----QRSAQR 1054
            |   :.::||:.|..:.|     |.....|        ::.|....:..||::|     .|....
plant   703 A---RKSSPREHSAGTNG-----FGTNGQT--------NEKSLQRWLDHELEVMVNVHEVRHEYE 751

  Fly  1055 LRRHCEAALLE 1065
            .:.|..|||.|
plant   752 KQSHVRAALAE 762

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	160/423 (38%)
		SMC_N	514..>615	CDD:481474	21/100 (21%)
		FHA_KIF14	627..741	CDD:438759	24/119 (20%)
FRA1	NP_199593.2	KISc_KIF4	10..371	CDD:276823	158/417 (38%)
		PRK03918	<384..909	CDD:235175	110/553 (20%)
		GumC	<480..>705	CDD:442439	64/336 (19%)