Protein Alignment neb and PAKRP1

DIOPT Version :10

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: NP_567423.1
• Gene: PAKRP1 / 827054
• AraportID: AT4G14150
• Length: 1292
• Species: Arabidopsis thaliana
• Alignment Length: 1284
• Identity: 302/1284 - (23%)
• Similarity: 497/1284 - (38%)
• Gaps: 360/1284 - (28%)

  Fly    52 NTAFSGSTPQPKPKPTALNACYTPSSLYRNANSTPG----RAKTPGTGKSSCSRTKER----DSL 108
            |.:.|.|.|..|.:....||    ..|.|| .|||.    |.|.|...:...|...:|    ::.
plant    23 NPSISKSKPPRKLRSAKENA----PPLDRN-TSTPDHRSMRMKNPLPPRPPPSNPLKRKLSAETA 82

  Fly   109 MESCLSVSEESNMIVAVRVRPLNALECTRGQVTNVVQVHGNSNELTVQAGSSADASAGVTHFFSY 173
            .||..|   :|.:.|.||::|||     :|:..:::....:.:.|||         :|.|  |::
plant    83 TESGFS---DSGVKVIVRMKPLN-----KGEEGDMIVEKMSKDSLTV---------SGQT--FTF 128

  Fly   174 DQVYYSCDPERKNFACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMG-IEALDDAA 237
            |.:   .:||    :.|.::|:....||::....|:|:.:||||||||||:|:|.| ...|.:..
plant   129 DSI---ANPE----STQEQMFQLVGAPLVENCLSGFNSSVFAYGQTGSGKTYTMWGPANGLLEEH 186

  Fly   238 LDGGPPHDEAGIIPRFCHELFRRI--EAVK-SQQQLQVEVEVSYFEIYNEKIHDLLSVQHAAAAT 299
            |.|    |:.|:.||....||.||  |.|| :::||..:...|..|||||:|.|||.
plant   187 LCG----DQRGLTPRVFERLFARIKEEQVKHAERQLNYQCRCSLLEIYNEQITDLLD-------- 239

  Fly   300 GESTPIQQQQQQQRPALKVREHPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRATASTAMNDKS 364
                |.|:.       |.:||....|.||.:|:...|.:.:.:...|..|...|.|.:|::|.:|
plant   240 ----PSQKN-------LMIREDVKSGVYVENLTEEYVKNLTDVSQLLIKGLGNRRTGATSVNTES 293

  Fly   365 SRSHSIFNIVLNLTDLSSDDGLSSDTDSSTASSLRQTRRSKISLVDLAGSERISVSGSNGERIRE 429
            ||||.:|..|:.....:..|||||            .:.|:|:|||||||||...:|:.|||::|
plant   294 SRSHCVFTCVVESRCKNVADGLSS------------FKTSRINLVDLAGSERQKSTGAAGERLKE 346

  Fly   430 GVSINKSLLTLGKVIAALADSRKAIANGPLGSGTPSTFVPYRESVLTWLLRENLGGNSKTVMLAT 494
            ..:||:||..||.:|..||:..:        :|.| ..:|||:|.||:||:|:||||:|..|:..
plant   347 AGNINRSLSQLGNLINILAEISQ--------TGKP-RHIPYRDSRLTFLLQESLGGNAKLAMVCA 402

  Fly   495 ISPASIHADETLATLRYACKARSIVNRVKVNESPHDKIIRDLRAEVDRLKSLRNEYERQRRLSGN 559
            :||:.....||.:|||:|.:|::|.|:..|||...|. :..||..:.:   ||:|.:|.:....|
plant   403 VSPSQSCRSETFSTLRFAQRAKAIQNKAVVNEVMQDD-VNFLRGVIHQ---LRDELQRMKNDGNN 463

  Fly   560 SNNP-----------------------VPRKI-------IIETSVDETEVEALRQQLAERERELS 594
            ..||                       .||.:       .||..:||..||.|..|:..:....|
plant   464 PTNPNVAYSTAWNARRSLNLLRSFGLGHPRSLPHEDNDGDIEMEIDEAAVERLCVQVGLQSSLAS 528

  Fly   595 RAQKSWMEKLK--EAEDQRKSELRVLKRRGLALE------------------------------- 626
            ......|.::|  .:.|.:..|.|:.:...:|:|
plant   529 EGINHDMNRVKSIHSSDGQSIEKRLPEDSDVAMEDACCHTENHEPETVDNMRTETETGIRENQIK 593

  Fly   627 -----------------------------------------------------------LTAEQK 632
                                                                       :.:...
plant   594 THSQTLDHESSFQPLSVKDALCSSLNKSEDVSSCPDLVPQDVTSANVLIADGVDDPEHLVNSASP 658

  Fly   633 QACLVNLTADPILSGTLFYLLPQGLVRIGRGRLPGG--SSSSQPD-----IVLD----GPLVA-- 684
            ..|:..:.|.|:|......:.|  .:|..|..|...  |::||.|     :|.:    .|..:
plant   659 SLCIDPVGATPVLKSPTLSVSP--TIRNSRKSLKTSELSTASQKDSEGENLVTEAADPSPATSKK 721

  Fly   685 LQHCS------------IEHER-GGKLYVIPGSEDFETYVNGELLKDRRQLFH------------ 724
            :.:||            :..|| ...|:  .|.:..|:|.  :....||..:.
plant   722 MNNCSSALSTQKSKVFPVRTERLASSLH--KGIKLLESYC--QSTAQRRSTYRFSFKAPDSEPST 782

  Fly   725 --------------GDRLVIGGSHYFRISNPFCSQRGKADH----------PVDFQLAHQEILQK 765
                          .|.:....:..|......|.::..|..          |||    :.|:.:|
plant   783 SISKADAGVQTIPGADAISEENTKEFLCCKCKCREQFDAQQMGDMPNLQLVPVD----NSEVAEK 843

  Fly   766 QEQQLRSELEAEKRAALTKIEQERAQHARDFEERLQCLELEQFKYKCNSEMLETERQALALAQQQ 830
            .:.|:...:|   :.....|.:|.|              ||:|..|..||:.:..|    |.||.
plant   844 SKNQVPKAVE---KVLAGSIRREMA--------------LEEFCTKQASEITQLNR----LVQQY 887

  Fly   831 EHTPLRHEDAV--STPAQKSTILEDIQRIMLNPSE-------ESLHKTQLMVKEATQRCRQLDLP 886
            :|.  |..:|:  .|...|...||.:...:|:..:       ..||:.:|:..........|...
plant   888 KHE--RECNAIIGQTREDKIIRLESLMDGVLSKEDFLDEEFASLLHEHKLLKDMYQNHPEVLKTK 950

  Fly   887 LEFRQTQTPDE-----FGLLRTVILILDKQRGLKAEWPTARLGVWLDLVRDNAEQQEKLNATTI- 945
            :|..:||...|     :|.:....::|::.:.||.:     |..::|     ...:..|...|:
plant   951 IELERTQEEVENFKNFYGDMGEREVLLEEIQDLKLQ-----LQCYID-----PSLKSALKTCTLL 1005

  Fly   946 ---FQSVEVDWEPLDADLNETLSDTHNSSRIALNLSAMKDVLLNKPLKRLLNASSSKSNTPRQTS 1007
               :|:..|:..|...|  |:|..|....|:....:..|.:.|::.|:..|.||.:..|..:..
plant  1006 KLSYQAPPVNAIPESQD--ESLEKTLEQERLCWTEAETKWISLSEELRTELEASKALINKQKHE- 1067

  Fly  1008 TPSPGSQLVHFTKRLLTYDPEEIPESQSSFTTLVQQELQIMQRSAQRLRRHCEAALLERENHQDN 1072
                    :...||.    .||:.|:..   ..::...:::::.|....:|.:  ||.|.....:
plant  1068 --------LEIEKRC----GEELKEAMQ---MAMEGHARMLEQYADLEEKHMQ--LLARHRRIQD 1115

  Fly  1073 GVLAVSLQEALARMDTVLNGMHTSLARAEATACVTSPTKTQKAVRFLID 1121
            |:  ..:::|.||..  :.|..:....|.|........:.:|..::|.|
plant  1116 GI--DDVKKAAARAG--VRGAESRFINALAAEISALKVEKEKERQYLRD 1160

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	143/409 (35%)
		SMC_N	514..>615	CDD:481474	30/132 (23%)
		FHA_KIF14	627..741	CDD:438759	26/165 (16%)
PAKRP1	NP_567423.1	PLN03188	2..1292	CDD:215621	302/1284 (24%)