Protein Alignment neb and si:dkey-26i13.8

DIOPT Version :10

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: XP_009304780.1
• Gene: si:dkey-26i13.8 / 797363
• ZFINID: ZDB-GENE-090312-134
• Length: 991
• Species: Danio rerio
• Alignment Length: 1029
• Identity: 262/1029 - (25%)
• Similarity: 422/1029 - (41%)
• Gaps: 286/1029 - (27%)

  Fly   118 ESNMIVAVRVRPLNALECTRGQVTNVVQVHGNSNELTVQAGSSADASAGVTHFFSYDQVY----- 177
            :..:.||:|:||||..|...|.   .:..|...|::.|......|:...:....|.::.|
Zfish    10 DHQLTVALRIRPLNEAEIEEGA---TIVAHKIDNQMVVLMDPCEDSDNVLRAHRSREKTYMFDLA 71

  Fly   178 --YSCDPERKNFACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMGIEALDDAALDG 240
              |:        |.|..|:..|.:.|||....||||.:||||.||:||:::|:|:::
Zfish    72 FDYT--------ATQEDVYVATTKNLIDGVIAGYNATVFAYGPTGAGKTHTMLGLDS-------- 120

  Fly   241 GPPHDEAGIIPRFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTPI 305
                 |.||..|..::|||.||  .|.:.|...|.:||.|||||.|.|||:         .|:..
Zfish   121 -----EPGIYIRTLNDLFRAIE--DSTEDLDCSVYMSYIEIYNEMIRDLLN---------PSSGY 169

  Fly   306 QQQQQQQRPALKVREHPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHSI 370
            .:.::..:..:::..       :.:.|..:.....||   |..||.||...|||.|..|||||:|
Zfish   170 LELREDGKGEIRIAG-------ITEFSTCNAKEIMAL---LTKGNKQRTQESTAANKTSSRSHAI 224

  Fly   371 FNIVLNLTDLSSDDGLSSDTDSSTASSLRQTRRSKISLVDLAGSERISVSGSNGERIREGVSINK 435
            ..:.:.......|..             .:.|..|:.:|||||:||.|.:.:.|:|::||..||:
Zfish   225 LQVTVKQKSRVKDIN-------------EEVRVGKLFMVDLAGTERASQTQNRGKRMKEGAHINR 276

  Fly   436 SLLTLGKVIAALADSRKAIANGPLGSGTPSTFVPYRESVLTWLLRENLGGNSKTVMLATISPASI 500
            |||.|...|.||::.          .|..:.||.||:|.||.||::.|||||:|||:..|||||.
Zfish   277 SLLALANCINALSEK----------GGKGAQFVNYRDSKLTRLLKDALGGNSRTVMITHISPASS 331

  Fly   501 HADETLATLRYACKARSIVNRVK---VNESPH----DKIIRDLRAEVDRLKSLRNEYERQRRLSG 558
            :.:|:..||.||.||::|..:||   :|.|.|    .:||.|||:|::||:: :.:.:.|.:|.|
Zfish   332 NFEESRNTLVYADKAKNIRTKVKRNLMNVSYHLAQYTRIIADLRSEIERLRA-KIDQQSQDQLKG 395

  Fly   559 NSNNPVPRKIIIET-SVDETEVEALRQQLAERERELSRAQKSWMEKLKEAEDQRKSELRVLKRRG 622
            ...:  .|.|..|. .....|:..|::||....||....::|.||.     :....||.:...|.
Zfish   396 EKAD--IRNIQAEVQQYSHGEMALLQEQLLSAFREQMEIRRSLMEL-----ENCNMELHIDTSRH 453

  Fly   623 LALELTAEQKQACLVNLTADPILSGTLFYLLPQGLVRIGRGRLPGGSSSSQPDIVLDGPLVALQH 687
            |......|:.:|                           |.|......|.|.           :|
Zfish   454 LLTISDWERDRA---------------------------RARREKDELSGQK-----------KH 480

  Fly   688 CSIEHERGGKLYVIPGSEDFETYVNGELLKDRRQLFHGDRLVIGGSHYFRISNPFCSQRGKADHP 752
            ...|.|:                   |.:.:..|.....|..||         |..::
Zfish   481 TDKEEEQ-------------------ESMPEEPQYVTAAREEIG---------PLLAE------- 510

  Fly   753 VDFQLAHQEILQKQEQQLRSELEAEK----RAALTKIEQERAQHARDFEER----LQC----LEL 805
                       |::..:|:.||| ||    :...:|||:...:...:.|:|    |.|    |||
Zfish   511 -----------QRKTMELKRELE-EKLLNMKLKSSKIEELLPKRISNTEQRDILMLLCKVHELEL 563

  Fly   806 EQFKYKCNSEMLETERQALALAQQQEHTPLRHED-AVSTPAQKSTILEDIQRIMLNPSEESLHKT 869
            |           :||.|:..|.::   ..||.:| .:....|:.|:.:||           :|:.
Zfish   564 E-----------KTEIQSAVLCKE---NVLRTKDFIIQRHEQQRTLCDDI-----------IHQQ 603

  Fly   870 QLMVKEATQRCRQLDLPLEFRQTQTPDEFGLLRTVILILDKQRGLKAEWPTARLG---VWLDLVR 931
            ::::::     :.|.:| |..|......||.|...  |:|:...|.. :.|..|.   :.||::
Zfish   604 KMLIED-----QGLCVP-EGLQELYSLYFGELSDG--IIDQILNLHT-FTTNNLNARQLRLDVI- 658

  Fly   932 DNAEQQEKLNATTIFQSVEVDWEPLDADLNETLSD----THNSSRIALNLSAMKDVLLNKPLKRL 992
            .|.|:.:|.      :...|.:.|||....::.|.    ..:::|:..:||.:|.       :|.
Zfish   659 SNLEEADKA------EQSNVKFSPLDKHPRDSSSSGLDYDSDTNRVFKSLSKIKP-------RRQ 710

  Fly   993 LNASSS----------KSNTP-RQTSTPSPGSQLVHFTKRLLTYDPEEIPESQSSFTTLVQQELQ 1046
            .::|||          |.:|| ..|.:.||.      |.|      |.:.:::|......::..:
Zfish   711 HHSSSSQTLMRKVCAVKDSTPICPTESVSPD------TLR------EIVSDTKSISVIAAKRRSR 763

  Fly  1047 IMQRSAQRLRRHCEAALLE-------------------RENHQDNGVLAVSLQE 1081
            :..:|..|:.....||.|:                   |.:||.:|..:.|.|:
Zfish   764 LQAKSNSRMAGMGLAAGLKSSVSMDSLVSTLPDESAEVRRSHQRHGGSSQSKQD 817

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	136/415 (33%)
		SMC_N	514..>615	CDD:481474	31/108 (29%)
		FHA_KIF14	627..741	CDD:438759	14/113 (12%)
si:dkey-26i13.8	XP_009304780.1	KISc_KIP3_like	12..349	CDD:276821	133/404 (33%)