Protein Alignment neb and Stard9

DIOPT Version :10

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: XP_017447698.1
• Gene: Stard9 / 691920
• RGDID: 1593360
• Length: 4604
• Species: Rattus norvegicus
• Alignment Length: 1018
• Identity: 294/1018 - (28%)
• Similarity: 454/1018 - (44%)
• Gaps: 229/1018 - (22%)

  Fly   119 SNMIVAVRVRPLNALECTRG---------QVTNVVQVHGNSNELTVQAGSSADASAGVTHFFSYD 174
            :|:.||||||||:..|...|         :|..|..|..||     :..|..|....|. .|.:|
  Rat     2 ANVQVAVRVRPLSKRETKEGGRIIVEVDDKVAKVRNVKVNS-----RLESFGDTREKVV-AFGFD 60

  Fly   175 QVYYSCDPERKNFACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMGIEALDDAALD 239
            ..|:|.:||..::|.|..||......::..|.:|||.||||||||||||:|:|:|..|
  Rat    61 YCYWSVNPEDPHYASQEVVFRDLGTEVLSGASKGYNICLFAYGQTGSGKTYTMLGTPA------- 118

  Fly   240 GGPPHDEAGIIPRFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTP 304
                  ..|:.||.|..||.|.:...|....: .::||:.|||||::.|||
  Rat   119 ------SVGLTPRICEGLFIREDDCASMPYSR-SIKVSFLEIYNERVRDLL-------------- 162

  Fly   305 IQQQQQQQRPALKVREHPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHS 369
             :|..|.:...|:|||||..||||..||.|:|.||..:...|..|.:.|.||:|.:::.|||||:
  Rat   163 -KQSNQNKSYTLRVREHPEMGPYVQGLSQHAVTSYQQVLQLLEEGIANRITAATHVHEASSRSHA 226

  Fly   370 IFNIVLNLTDLSSDDGLSSDTDSSTASSLRQTRRSKISLVDLAGSERISVSGSNGERIREGVSIN 434
            ||.|  :.|..:..:.|.|:|            .|||:|||||||||...|... :||.||.:||
  Rat   227 IFTI--HCTQATLQNNLPSET------------ASKINLVDLAGSERADPSYCK-DRITEGANIN 276

  Fly   435 KSLLTLGKVIAALA---------DSRKAIANGPLGSGTPST---------------FVPYRESVL 475
            |||:|||.||:.||         .|..:.|:....||.|||               ::|||:|||
  Rat   277 KSLVTLGIVISTLAQNSQVFSSCQSLSSAASSGGDSGIPSTTSGTSSGGGPARRQSYIPYRDSVL 341

  Fly   476 TWLLRENLGGNSKTVMLATISPASIHADETLATLRYACKARSIVNRVKVNESPHDKIIRDLRAEV 540
            ||||:|:|||||||:|:||:|||.....||::|:|||..|::|:|:.:|||..:.|:||:||.|:
  Rat   342 TWLLKESLGGNSKTIMVATVSPAHTSYSETMSTMRYASNAKNIINKPQVNEDANVKLIRELREEI 406

  Fly   541 DRLKSLRNEYERQRRLSGNSNNPVPRKIIIETSVDETEVEALRQQLAERERELSRAQKSWMEKLK 605
            :|||::...:|.:...|.|               |:.: |:|::.:.:.:.::....:.|.:|
  Rat   407 ERLKAMLLNFELRNFSSLN---------------DDLD-ESLQELVFQNDLKIDTLTQHWTQK-- 453

  Fly   606 EAEDQRKSELRVLKRRGLAL-----ELTAEQKQACLVNLTADPILSGTLFYLLPQGLVRIGRGRL 665
              .:.|::   :::..|:.:     .:..:.....|:.|..|.:.:|.:.|.|.:|..||||
  Rat   454 --PNNRQA---LMEHYGVGINRNRARVVIDSSLPHLMALEDDVLSTGIVLYHLKEGTTRIGR--- 510

  Fly   666 PGGSSSSQPDIVLDGPLVALQHCSIEHERGGKLYVIPGSEDFETYVNGELLKDRRQLFHGDRLVI 730
              ..|..:.||||.|..:...||:|....|  :.::..|:.....|||..:....:|..|..:.:
  Rat   511 --IDSDQEQDIVLQGQWIERDHCTITSTCG--VVILRPSQGARCTVNGREVTASCRLTQGAVITL 571

  Fly   731 GGSHYFRISNPFCSQRGKADHPVDFQLAHQEILQKQE----------QQLRSELEAEKRAALTKI 785
            |.:..||.           :||.:.....||.|:..|          ..|..::.|.:......:
  Rat   572 GKAQKFRF-----------NHPAEAAALRQERLKVGEVLGSSGSLEWLDLDGDVSASRLGLCPVL 625

  Fly   786 EQERAQHARDFEERLQCLELEQFKYKCNSEMLETERQALALAQQQEHTPLRHEDAVSTPAQ--KS 848
            .:||.......::..|.|...:..|:..:|            |||.|.     :|:...|:  :|
  Rat   626 RKERRVLEEQSDKDQQPLRNGKISYRAQTE------------QQQCHV-----EALKQQAKEGQS 673

  Fly   849 TILEDIQRIMLNPSEESLHKTQLMVKEATQRCRQLDLPLEFRQTQ---------------TPDEF 898
            .:.::::....:.:.:.....|.:::|.|...       ..|:||               .||.:
  Rat   674 RVQKELKLDQTHINRKITDNQQWLLREETWLS-------NLRETQQEGDCGEEKELEAFVAPDAW 731

  Fly   899 GLLRTV------ILILDKQRGLKAEW---PTARLGVW----------LDLV---RDNAEQQ---E 938
              |.||      .|:..::|.::...   .|:|..||          |:.:   |...|.|   |
  Rat   732 --LPTVPQTPPSPLVQSQKRVVQPRCLRKHTSRATVWNIRQKKVSFQLERIIKKRRLLEAQRRLE 794

  Fly   939 KLNATTIFQ----SVEVDWEPLDADLNETLSDTHNSSRIALNLSAMKDVLLNKPLKRLLNASSSK 999
            :|||....|    |....|.   :..|.|.|.:...||.....|.....|.::.|.:|.:|..:.
  Rat   795 QLNALFWIQDNGTSKAPSWA---SSSNTTGSGSQRRSRWTTCSSLSLQRLCSQRLSQLRSAVMNW 856

  Fly  1000 SNTPRQTSTPSPGSQLVHFTKRLLTYDPEEIPESQSSFTTLVQ 1042
            .  |...|.|.|.          ||   :::||...|..|:.|
  Rat   857 D--PSAMSPPVPD----------LT---QQMPEKTLSTDTVPQ 884

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	172/438 (39%)
		SMC_N	514..>615	CDD:481474	24/100 (24%)
		FHA_KIF14	627..741	CDD:438759	30/113 (27%)
Stard9	XP_017447698.1	KISc_KIF1A_KIF1B	2..391	CDD:276816	172/438 (39%)
		Kinesin_assoc	390..504	CDD:465047	28/136 (21%)
		FHA	475..592	CDD:469597	33/134 (25%)
		AtpF	<4207..>4247	CDD:440475
		SRPBCC	4378..4552	CDD:472699