Protein Alignment neb and Stard9

DIOPT Version :10

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: XP_036018388.1
• Gene: Stard9 / 668880
• MGIID: 3045258
• Length: 4598
• Species: Mus musculus
• Alignment Length: 1125
• Identity: 303/1125 - (26%)
• Similarity: 462/1125 - (41%)
• Gaps: 292/1125 - (25%)

  Fly   119 SNMIVAVRVRPLNALECTRGQVTNVVQVHGNSNELTVQAGSSADASAGVTH----FFSYDQVYYS 179
            :|:.||||||||:..|...|. ..:|:|.....::......|...|.|.|.    .|.:|..|:|
Mouse     2 ANVQVAVRVRPLSKRETKEGG-RIIVEVDDKVAKIRNVKVDSRPESFGDTREKVVAFGFDYCYWS 65

  Fly   180 CDPERKNFACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMGIEALDDAALDGGPPH 244
            .:||..::|.|..||......::..|.:|||.||||||||||||:|:|:|..|
Mouse    66 VNPEDPHYASQEVVFRDLGTEVLSGAAKGYNICLFAYGQTGSGKTYTMLGTPA------------ 118

  Fly   245 DEAGIIPRFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTPIQQQQ 309
             ..|:.||.|..||.|.:...| |.....::||:.|||||::.|||               :|..
Mouse   119 -SVGLTPRICEGLFIREDDCAS-QPCSRSIKVSFLEIYNERVRDLL---------------KQSN 166

  Fly   310 QQQRPALKVREHPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHSIFNIV 374
            |.:...|:|||||..||||..||.|.|.:|..:...|..|.:.|.||:|.:::.|||||:||.|
Mouse   167 QNKSYTLRVREHPEMGPYVQGLSQHVVTNYQQVIQLLEAGIANRITAATHVHEASSRSHAIFTI- 230

  Fly   375 LNLTDLSSDDGLSSDTDSSTASSLRQTRRSKISLVDLAGSERISVSGSNGERIREGVSINKSLLT 439
             :.|.....:.|.|:|            .|||:|||||||||...|... :||.||.:|||||:|
Mouse   231 -HCTQAILQNNLPSET------------ASKINLVDLAGSERADPSYCK-DRITEGANINKSLVT 281

  Fly   440 LGKVIAALA---------DSRKAIANGPLGSGTPST---------------FVPYRESVLTWLLR 480
            ||.||:.||         .|..:.|:....||.|||               ::|||:|||||||:
Mouse   282 LGIVISTLAQNSQVFSSCQSLSSAASSGGDSGVPSTTSGASSGGGPARRQSYIPYRDSVLTWLLK 346

  Fly   481 ENLGGNSKTVMLATISPASIHADETLATLRYACKARSIVNRVKVNESPHDKIIRDLRAEVDRLKS 545
            |:|||||||:|:||:|||.....||::|:|||..|::|:|:.:|||..:.|:||:||.|::|||:
Mouse   347 ESLGGNSKTIMVATVSPAHTSYSETMSTMRYASNAKNIINKPRVNEDANVKLIRELREEIERLKA 411

  Fly   546 LRNEYERQRRLSGNSNNPVPRKIIIETSVDETEVEALRQQLAERERELSRAQKSWMEKLKEAEDQ 610
            :...:|.:...|.|               |:.: |:|::.:.:.:.::....:.|.||
Mouse   412 VLLNFELRNFSSLN---------------DDLD-ESLQELVFQSDLKIDTLTQHWTEK------- 453

  Fly   611 RKSELRVLKRRGLAL-----ELTAEQKQACLVNLTADPILSGTLFYLLPQGLVRIGRGRLPGGSS 670
            |.....:::..|:.:     .:..:.....|:.|..|.:.:|.:.|.|.:|..:|||     ..|
Mouse   454 RNDRQALMEHYGVDINRKRARVVIDSSLPHLMALEDDVLSTGVVLYHLKEGTTKIGR-----IDS 513

  Fly   671 SSQPDIVLDGPLVALQHCSIEHERGGKLYVIPGSEDFETYVNGELLKDRRQLFHGDRLVIGGSHY 735
            ..:.||||.|..:...||:|....|  :.::..::.....|||      |::....||..|..
Mouse   514 DQEQDIVLQGQWIERDHCTITSTCG--VVILRPTQGARCTVNG------REVTASCRLTQGRD-- 568

  Fly   736 FRISNPFC----------SQRGKADHPVDFQLAHQEILQKQEQ----------QLRSELEAEKRA 780
            :.:::.:|          :|:.:.:||.:..:...:.|:..|.          .|..::.|.:..
Mouse   569 YGLNSGWCVTGAVITLGKAQKFRFNHPAEAAVLRHQRLKVGEALGSSGSLEWLDLDGDVSASRLG 633

  Fly   781 ALTKIEQERAQHARDFEERLQCLELEQFKYKCNSEMLETERQALALAQQQEHTPLRHEDAVSTPA 845
            ....:.:||    |..||  ||                          .::..|.||.: :...|
Mouse   634 LCPVLRKER----RVLEE--QC--------------------------DRDQQPSRHSE-IPYRA 665

  Fly   846 QKSTILEDIQRIMLNPSEESLHKTQL--MVKEATQRCRQLDLPLEFRQTQTPDEFGLLRTVILIL 908
            |              |.::..|...|  ..||...|.::   .||...|....:         |.
Mouse   666 Q--------------PEQQQCHVEALKQQAKEGQSRVQK---ELELDHTHISQQ---------IK 704

  Fly   909 DKQRGLKAEWPTARLGVWLDLVRD-----NAEQQEKLNATTIFQSVEVD-WEPLDAD-------- 959
            |.|:.|..|      ..||..:|:     |..::::|.|     ||..| |.|....
Mouse   705 DNQQWLLTE------ETWLASLRETQQEGNCGEEKELEA-----SVAPDAWLPTVPQTPPSPLVQ 758

  Fly   960 -----LNETLSDTHNSSRIALNLSAMK-----DVLLNKPLKRLLNA--------------SSSKS 1000
                 :....|..|.:.....|:...|     :.::.|  :|||.|              ....|
Mouse   759 SQKRVVQPQCSPRHTTRATVWNIRQKKVSFQLERIIKK--RRLLEAQRRLEQLSTFFWIQDDGAS 821

  Fly  1001 NTP---RQTSTPSPGSQ--------------------LVHFTKRLLTYDPEEIPESQSSFTTLVQ 1042
            ..|   ..::|..||||                    |.......:.:||..:.......|
Mouse   822 RAPSWASSSNTSGPGSQRRSRWTTCSSLSLQRLGCRRLPQLHSDFMNWDPSAMSPPVPELT---- 882

  Fly  1043 QELQIMQRSAQRLRRHC---EAALLERENHQDNGVLAVSLQEALARMDTVLNGMHTSLARAEATA 1104
                 .|...:.|...|   :|..|.|.:...:.....|.....:...|.|...|.|::..|..:
Mouse   883 -----HQMPEKTLSTDCIPPKAGRLGRNSFHSSRWRKFSPARRASTQGTHLTVSHKSVSSQEIES 942

  Fly  1105 CVTSP---------TKTQKA 1115
            ....|         ||.|||
Mouse   943 LGKQPCQMSSQGQSTKKQKA 962

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	170/433 (39%)
		SMC_N	514..>615	CDD:481474	25/100 (25%)
		FHA_KIF14	627..741	CDD:438759	27/113 (24%)
Stard9	XP_036018388.1	KISc_KIF1A_KIF1B	2..391	CDD:276816	170/433 (39%)
		Kinesin_assoc	390..504	CDD:465047	29/136 (21%)
		FHA	475..605	CDD:469597	31/144 (22%)
		SRPBCC	4394..4598	CDD:472699