Protein Alignment neb and STARD9

DIOPT Version :9

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: XP_011520133.1
• Gene: STARD9 / 57519
• HGNCID: 19162
• Length: 4705
• Species: Homo sapiens
• Alignment Length: 1099
• Identity: 300/1099 - (27%)
• Similarity: 476/1099 - (43%)
• Gaps: 296/1099 - (26%)

  Fly   119 SNMIVAVRVRPLNALECTRGQVTNVVQVHGNSNEL-TVQAGSSADA---SAGVTHFFSYDQVYYS 179
            :|:.||||||||:..|...|. ..:|:|.|...:: .::..:..|.   |......|.:|..|:|
Human     2 ANVQVAVRVRPLSKRETKEGG-RIIVEVDGKVAKIRNLKVDNRPDGFGDSREKVMAFGFDYCYWS 65

  Fly   180 CDPERKNFACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMGIEALDDAALDGGPPH 244
            .:||...:|.|..||:.....::....:|||.||||||||||||:|:|:|..|
Human    66 VNPEDPQYASQDVVFQDLGMEVLSGVAKGYNICLFAYGQTGSGKTYTMLGTPA------------ 118

  Fly   245 DEAGIIPRFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTPIQQQQ 309
             ..|:.||.|..||.|.:...|... ...::||:.|||||::.|||               :|..
Human   119 -SVGLTPRICEGLFVREKDCASLPS-SCRIKVSFLEIYNERVRDLL---------------KQSG 166

  Fly   310 QQQRPALKVREHPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHSIFNIV 374
            |::...|:|||||..||||..||.|.|.:|..:...|..|.:.|.||:|.:::.|||||:||.|
Human   167 QKKSYTLRVREHPEMGPYVQGLSQHVVTNYKQVIQLLEEGIANRITAATHVHEASSRSHAIFTI- 230

  Fly   375 LNLTDLSSDDGLSSDTDSSTASSLRQTRRSKISLVDLAGSERISVSGSNGERIREGVSINKSLLT 439
             :.|....::.|.|:            ..|||:|||||||||...|... :||.||.:|||||:|
Human   231 -HYTQAILENNLPSE------------MASKINLVDLAGSERADPSYCK-DRIAEGANINKSLVT 281

  Fly   440 LGKVIAALADS----------RKAIANG--------PLGS---GTPS---TFVPYRESVLTWLLR 480
            ||.||:.||.:          ..:::||        |.|:   |.||   :::|||:|||||||:
Human   282 LGIVISTLAQNSQVFSSCQSLNSSVSNGGDSGILSSPSGTSSGGAPSRRQSYIPYRDSVLTWLLK 346

  Fly   481 ENLGGNSKTVMLATISPASIHADETLATLRYACKARSIVNRVKVNESPHDKIIRDLRAEVDRLKS 545
            ::|||||||:|:||:|||.....||::|||||..|::|:|:.:|||..:.|:||:||.|::|||:
Human   347 DSLGGNSKTIMVATVSPAHTSYSETMSTLRYASSAKNIINKPRVNEDANLKLIRELREEIERLKA 411

  Fly   546 LRNEYERQRRLSGNSNNPVPRKIIIETSVDETEVEALRQQLAERERELSRAQKSWMEKLKEAEDQ 610
            |...:| .|..|..|:                  |.|::.:.:.|.::.:..|.|.:|..:.:..
Human   412 LLLSFE-LRNFSSLSD------------------ENLKELVLQNELKIDQLTKDWTQKWNDWQAL 457

  Fly   611 RKSELRVLKRR--GLALELTAEQKQACLVNLTADPILSGTLFYLLPQGLVRIGRGRLPGGSSSSQ 673
            .:.....:.||  |:.::.:...    |:.|..|.:.:|.:.|.|.:|..:|||     ..|..:
Human   458 MEHYSVDINRRRAGVVIDSSLPH----LMALEDDVLSTGVVLYHLKEGTTKIGR-----IDSDQE 513

  Fly   674 PDIVLDGPLVALQHCSIEHERGGKLYVIPGSEDFETYVNGELLKDRRQLFHGDRLVIGGSHYFRI 738
            .||||.|..:...||:|....|  :.|:..:......|||..:....:|..|..:.:|.:..||.
Human   514 QDIVLQGQWIERDHCTITSACG--VVVLRPARGARCTVNGREVTASCRLTQGAVITLGKAQKFRF 576

  Fly   739 SNP----FCSQR---GKA----------------------------------------DH--PVD 754
            ::|    ...||   |:|                                        ||  |.|
Human   577 NHPAEAAVLRQRRQVGEAAAGRGSLEWLDLDGDLAASRLGLSPLLWKERRALEEQCDEDHQTPRD 641

  Fly   755 FQLAHQEILQKQE---QQLRSELEAEKRAALTKIEQERAQHARDFEERLQCLELEQFKYKCNSEM 816
            .:.:|:..:|:|:   :.||.::.||:..|..::|.::|..::..:|..|||
Human   642 GETSHRAQIQQQQSYVEDLRHQILAEEIRAAKELEFDQAWISQQIKENQQCL------------- 693

  Fly   817 LETERQALALAQQQEHTPLRHEDAVSTPAQKSTI-----LEDIQRIMLNPSEES---------LH 867
            |..|....:|.|||:      ||.|:....::::     |:....|..:|..:|         |.
Human   694 LREETWLASLQQQQQ------EDQVAEKELEASVALDAWLQTDPEIQPSPFVQSQKRVVHLQLLR 752

  Fly   868 KTQLMVKEATQRCRQLDLPLEFRQTQTPDEFGLLRTVILILDKQRGLKAEWPTARLGV--WLDLV 930
            :..|...|...|.:::...||                 .|:.|||.|:|:....:|..  ||
Human   753 RHTLRAAERNVRRKKVSFQLE-----------------RIIKKQRLLEAQKRLEKLTTLCWL--- 797

  Fly   931 RDNAEQQ------------------EKLNATTI-------------FQSVEVDWEPLDADLNETL 964
            :|::.|:                  .||.:.:.             ..|:.:.|:| ...|....
Human   798 QDDSTQEPPYQVLSPDATVPRPPCRSKLTSCSSLSPQRLCSKHMPQLHSIFLSWDP-STTLPPRP 861

  Fly   965 SDTHNSSRIALNLSAMKDVLLNKPLKRLLNASSSKSNTPRQTSTPS-----------------PG 1012
            ..||.:|                      ..:||:.:.|:..|.|:                 |.
Human   862 DPTHQTS----------------------EKTSSEEHLPQAASYPARTGCLRKNGLHSSGHGQPC 904

  Fly  1013 SQLVHFTKR-------LLTYDPEEIPESQSSFTT-----LVQQELQIMQRSAQRLR-RH 1058
            :......::       .||..|..:...:.....     :|.|.|..:::||.:|: ||
Human   905 TARAALARKGASAPDACLTMSPNSVGIQEMEMGVKQPHQMVSQGLASLRKSANKLKPRH 963

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	166/433 (38%)
		KISc	120..525	CDD:214526	166/432 (38%)
		Kinesin_assoc	524..657	CDD:292801	32/134 (24%)
		FHA	634..740	CDD:238017	29/105 (28%)
STARD9	XP_011520133.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123768at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820