Protein Alignment neb and kif1c

DIOPT Version :9

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: XP_009300278.1
• Gene: kif1c / 570771
• ZFINID: ZDB-GENE-090312-119
• Length: 1185
• Species: Danio rerio
• Alignment Length: 1163
• Identity: 336/1163 - (28%)
• Similarity: 510/1163 - (43%)
• Gaps: 313/1163 - (26%)

  Fly   119 SNMIVAVRVRPLNALECTRGQVTNVVQVHGNSNELT--VQAGSSADASAGVTHFFSYDQVYYS-C 180
            |::.|||||||.|:.|..|| ...|:|:...|..:|  .|...|...       |::|..|:| .
Zfish     4 SSVKVAVRVRPFNSRETNRG-AKCVIQMQDKSTCITNPKQPKESPKN-------FTFDYSYWSHS 60

  Fly   181 DPERKNFACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMGIEALDDAALDGGPPHD 245
            ..|..:||.|.||::.....::..||||||.|:|||||||:||||:|||.:       |.|
Zfish    61 SEEDPSFASQRKVYQDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQ-------DPG---- 114

  Fly   246 EAGIIPRFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTPIQQQQQ 310
            :.||||:.|.:|||: .|..:...|...|||||.|||.|::.|||:                  .
Zfish   115 QQGIIPQMCEDLFRQ-TAENTDPDLSFSVEVSYMEIYCERVRDLLN------------------P 160

  Fly   311 QQRPALKVREHPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHSIFNIVL 375
            :.:.||:||||||.||||.|||..:|.:||.:.:.:..||..|..|:|.||:.|||||::|.|:
Zfish   161 KSKGALRVREHPIMGPYVEDLSKMAVTNYSDIADLMDTGNKARTVAATNMNETSSRSHAVFTIL- 224

  Fly   376 NLTDLSSDDGLSSDTDSSTASSLRQTRRSKISLVDLAGSERISVSGSNGERIREGVSINKSLLTL 440
             .|....|...|.||:          :.|||||||||||||...||:.|.|::||.:|||||.||
Zfish   225 -FTQHRHDHMTSLDTE----------KVSKISLVDLAGSERADSSGAKGMRLKEGANINKSLTTL 278

  Fly   441 GKVIAALADSRKAIANGPLGSGTPSTFVPYRESVLTWLLRENLGGNSKTVMLATISPASIHADET 505
            ||||:||||......:|  .....|.|:|||:|||||||||||||||:|.|:|.:|||.|:.:||
Zfish   279 GKVISALADMVSPPQHG--SKKRRSDFIPYRDSVLTWLLRENLGGNSRTAMIAALSPADINYEET 341

  Fly   506 LATLRYACKARSIVNRVKVNESPHDKIIRDLRAEVDRLKSL------------RNEYERQRRLSG 558
            |:|||||.:|:.|.....:||.|:.:::|:|:.||:|||.|            .........|:|
Zfish   342 LSTLRYADRAKQIKCNAVINEDPNARLVRELKEEVNRLKELLLSQGLSNLITASGSETGHPALAG 406

  Fly   559 -------------NSNNPVPRKIIIETSVDE-TEVEALRQQLAERERELSRAQKSWMEKLKEAED 609
                         .|.:..|.:.:..||..| ...|...::|.|.|:.::...::|.|||::.|:
Zfish   407 VLGEPHQPSLPYVQSTSDAPMEGVTTTSPSEPISKEEAAERLKETEKIIAELNETWEEKLRKTEE 471

  Fly   610 QRKSELRVLKRRGLALE-------LTAEQKQACLVNLTADPILSGTLFYLLPQGLVRIGRGRLPG 667
            .|:....:|...|::::       :.:.:|...||||..||::|..|.|.:..|:.|:|:
Zfish   472 IRQDRESLLAEMGVSVKEDGGTVGVFSPKKTPHLVNLNEDPLMSECLIYYIKDGVTRVGQ----- 531

  Fly   668 GSSSSQPDIVLDGPLVALQHCSIEHERGGKLYVIPGSEDF---ETYVNGELLKDRRQLFHGDRLV 729
                ...||.|.|..:...||....|......|:...|..   ||||||:.:.:...|..|:|:|
Zfish   532 ----EDVDIRLSGQFIKELHCVFCSEINENNEVVVTLEPLVGAETYVNGKQVTEGVVLKQGNRIV 592

  Fly   730 IGGSHYFRISNP-----------FCSQRGKADHPVDFQLAHQEILQKQEQQLRSELEAEKRAALT 783
            :|.:|.||.::|           ...|:|:   |||:..|.:|:|:||...::.|:|       .
Zfish   593 MGKNHVFRFNHPEQARLERERSATQEQQGE---PVDWSYAQKELLEKQGIDIKQEME-------K 647

  Fly   784 KIEQERAQHARDFEERLQCLELEQF-----------KYKCNS--EMLETERQALALAQQQ----- 830
            :::....|:.::.||..|.||.::.           |..|..  .::.:.|:.|...:.|
Zfish   648 RLQDLENQYRKEKEEADQILEQQRLYADSDSGDDSDKRSCEESWRLISSLREKLPANKMQSIVKK 712

  Fly   831 --------EHTPLRHEDAVSTPAQKSTILEDIQRIMLNPSEESLHKTQLMVKE-ATQRCRQL--D 884
                    ...|||             :.:..||..:..::||  |.:|.|:| .||..:::  :
Zfish   713 CGLPSSGKRREPLR-------------VYQIPQRRRIPATQES--KQRLSVEELRTQAVKEICYE 762

  Fly   885 LPL-EFRQTQTPDEFGLLRTVILILDKQRGLKAEWPTARLGVWLDLVRD----------NAEQQE 938
            :.| :|:.|:...|   ...::.:.:..|....:.|..| ..|..:.:|          ..::::
Zfish   763 VALGDFKHTRQEIE---ALAIVRMKELCRTYCQKDPQER-ETWKSVAKDVCETVGIGEEEGDRED 823

  Fly   939 KLNA------------------------TTIFQSVEV-----DWE---------------PLD-- 957
            ::.|                        |.|.|.|::     |.|               |:|
Zfish   824 RIAAAAAGGGSEGGKTDMGDLKAHIDKLTDILQEVKLQNNMKDEEIRSLRDRMVKMEKIFPVDVK 888

  Fly   958 -----------------ADLNETLSDT---------------HNSSRIALNLSAMKDVLLNKPLK 990
                             |.:|....|:               |:..|        :....|:|..
Zfish   889 GDDEDVEFGGARVEEPTAQVNRRNEDSGYRRGRHRWQYPEKYHDPKR--------RKGANNQPNN 945

  Fly   991 RL------------LNASSSKSNTPRQTSTPS--PGSQLVHFTKRLLTYDPEEI----------- 1030
            .|            .|.:||:.:.|...|.||  |....:..|.|.|.....::
Zfish   946 ALYTPPPGHSQNNPFNTASSRPSNPSFNSQPSRNPNGPFLPGTGRFLPPQDRKLQFPFKNNPQHR 1010

  Fly  1031 -----------PESQSSFTTLVQQELQIMQRS----AQRLRRHCEAALLERENHQDNG 1073
                       |.:|||..|   .|:...|.|    .|....|.:    :|.||.:.|
Zfish  1011 GFNWGPCGNQEPAAQSSLNT---DEVHTFQSSPSPKPQWPNNHHQ----QRRNHGNRG 1061

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	182/408 (45%)
		KISc	120..525	CDD:214526	181/407 (44%)
		Kinesin_assoc	524..657	CDD:292801	40/165 (24%)
		FHA	634..740	CDD:238017	35/108 (32%)
kif1c	XP_009300278.1	KISc_KIF1A_KIF1B	4..361	CDD:276816	182/408 (45%)
		KISc	5..361	CDD:214526	181/407 (44%)
		Kinesin_assoc	358..526	CDD:292801	40/167 (24%)
		FHA	503..603	CDD:238017	35/108 (32%)
		FHA	<513..601	CDD:224630	28/96 (29%)
		MPLKIP	967..>1099	CDD:292140	22/102 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D76316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920