Protein Alignment neb and si:ch73-375g18.1

DIOPT Version :10

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: XP_073795542.1
• Gene: si:ch73-375g18.1 / 562945
• ZFINID: ZDB-GENE-110408-56
• Length: 1174
• Species: Danio rerio
• Alignment Length: 1069
• Identity: 313/1069 - (29%)
• Similarity: 482/1069 - (45%)
• Gaps: 253/1069 - (23%)

  Fly   123 VAVRVRPLNALECTRGQVTNVVQVHGNSNEL--TVQAGSSADASAGVTHFFSYDQVYYS----CD 181
            |||||||.|:.| .......|:|:.||:..:  ..|...||..       ||:|..|:|    .|
Zfish     7 VAVRVRPFNSRE-NNHDAKCVIQMQGNTTCIYNPKQPKESAKN-------FSFDYSYWSHSTEDD 63

  Fly   182 PERKNFACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMGIEALDDAALDGGPPHDE 246
            |.   |..|.:|:......::..||||||.|:|||||||:||||:|||.:       :.|    :
Zfish    64 PA---FVSQRQVYLDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQ-------EPG----Q 114

  Fly   247 AGIIPRFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTPIQQQQQQ 311
            .||||:.|.:||:| .:.....:|...||||:.|||.|::.|||:                  .:
Zfish   115 QGIIPQMCEDLFKR-TSENIDPELSYSVEVSFMEIYCERVRDLLN------------------PK 160

  Fly   312 QRPALKVREHPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHSIFNIVLN 376
            .:.||:||||||.||||.|||..:|.||..:|:.:..||..|..|:|.||:.|||||::|.||
Zfish   161 SKGALRVREHPIMGPYVEDLSKLAVTSYDDIRDLMDAGNKARTVAATNMNETSSRSHAVFTIV-- 223

  Fly   377 LTDLSSDDGLSSDTDSSTASSLRQTRRSKISLVDLAGSERISVSGSNGERIREGVSINKSLLTLG 441
            .|....|...:.||:          :.||:||||||||||...||:.|.|::||.:|||||.|||
Zfish   224 FTQHRRDQMTNLDTE----------KVSKVSLVDLAGSERADSSGAKGLRLKEGANINKSLTTLG 278

  Fly   442 KVIAALADSRKAIANGPLGSGTPSTFVPYRESVLTWLLRENLGGNSKTVMLATISPASIHADETL 506
            |||:|||:.:.:       ....|.|:|||:|||||:|:|||||||:|.|:|.:|||.|:.:|||
Zfish   279 KVISALAEMQSS-------KRRKSEFIPYRDSVLTWILKENLGGNSRTAMIAALSPADINYEETL 336

  Fly   507 ATLRYACKARSIVNRVKVNESPHDKIIRDLRAEVDRLKSLRNEYERQRRLSG-----NSNN---- 562
            :|||||.:|:.|.....:||.|:.::||:|:.||:||:.|.......|.::.     |:|:
Zfish   337 STLRYADRAKQIRCNAVINEDPNARLIRELKEEVNRLRDLLLSQGLSRLMTAPAAEVNNNSVGVT 401

  Fly   563 ----------------PVPRK----------IIIETSVDETEVEAL-----RQQLAERERELSRA 596
                            |:|.:          :...:.::|.:.|.:     .::|.|.|:.::..
Zfish   402 LMPAESASNGAPPTSAPIPGEGPAPESDPAPLDDHSQLEEFQGEMITNEEAAERLKETEKIIAEL 466

  Fly   597 QKSWMEKLKEAEDQRKSELRVLKRRGLALE-------LTAEQKQACLVNLTADPILSGTLFYLLP 654
            .::|.|||::.|..|.....:|...|::::       :.:.:....||||..||::|..|.|.:.
Zfish   467 NETWEEKLRKTESIRLERESILAEMGVSIKEDGGTVGVFSPKGTPHLVNLNEDPLMSECLLYYIK 531

  Fly   655 QGLVRIGRGRLPGGSSSSQPDIVLDGPLVALQHC---SIEHERGGKLYVIPGSEDFETYVNGELL 716
            :|:.|:|:         ...||.|.|..:..:||   |..:..||....:...|..||||||:.:
Zfish   532 EGVTRVGQ---------KDVDIKLSGQFIKEKHCVFYSYMNHNGGVDVTLEPLEGAETYVNGKQI 587

  Fly   717 KDRRQLFHGDRLVIGGSHYFRISNP----------FC-SQRGKADHPVDFQLAHQEILQKQEQQL 770
            .:...|..|:|:|:|.||.||.::|          .| .|:|:   |.|:..|.:|:|:||...:
Zfish   588 SECVLLRQGNRIVMGKSHVFRFNHPEQARLERERSTCVEQQGE---PADWNYAQRELLEKQGIDI 649

  Fly   771 RSELE-----------AEKRAALTKIEQERA---------QHARDFEERLQCLELEQFKYKCNSE 815
            :.|:|           .||..|...:||:|.         ...|..||..:.:...:.|...|..
Zfish   650 KLEMERRLQDVEIQYRREKEEADLLLEQQRLYADSDSGDDSDKRSCEESWRLISSLREKLPANKV 714

  Fly   816 MLETERQALALAQQQEHTPLRHEDAVSTPAQKSTILEDIQRIMLNPSEESLHKTQLMVKEATQRC 880
            ....:|..|. :..:...|||             :.:..||..::.:.|.|..:.|.::...:.|
Zfish   715 QSIVKRCGLP-SSGKRREPLR-------------VYQIPQRRRISKAPEQLTLSDLKLQAVKEIC 765

  Fly   881 RQLDLPLEFRQTQTPDEFGLLRTVILILDKQRGL----------KAEWPTARLGVWLDLVRDNAE 935
            .::.|. :||.::...|       .|.:.|.:.|          |..|......||
Zfish   766 YEVALG-DFRHSRREVE-------ALAIVKMKELCRMYGRRDAEKDGWREVAEDVW--------- 813

  Fly   936 QQEKLNATTIFQSVEVDWEPLDADLNETLSDTHNSSRIALNLSAMKDVLLN------------KP 988
                   .|:....|...:..|||.....|..:|   :..::..:.|:|..            |.
Zfish   814 -------ETVGIGDERTQDTADADAESARSGVYN---LKAHIHKLTDILQEVKEQNNMKDEEIKA 868

  Fly   989 LK-RLLNASS----SKSNTPRQTSTPSPGSQ-------------LVHFTKRLLTYDP-------E 1028
            |: |::...|    .:.:.......|..|.|             ......||:..||       .
Zfish   869 LRDRMMKMESIIPVVQQDDDESEDLPPDGDQGRGLDEDDHGCVPKEERVSRLMEEDPAFRRGRMR 933

  Fly  1029 EIPESQSSFTTLVQQELQIMQRSAQRLRR 1057
            .:.:.|.....|.||::      .:||||
Zfish   934 WLKQEQMRLQNLQQQQI------TKRLRR 956

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	173/407 (43%)
		SMC_N	514..>615	CDD:481474	29/140 (21%)
		FHA_KIF14	627..741	CDD:438759	37/116 (32%)
si:ch73-375g18.1	XP_073795542.1	None