Protein Alignment neb and Kif17

DIOPT Version :10

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: XP_038967234.1
• Gene: Kif17 / 500571
• RGDID: 1562511
• Length: 1075
• Species: Rattus norvegicus
• Alignment Length: 1115
• Identity: 293/1115 - (26%)
• Similarity: 450/1115 - (40%)
• Gaps: 290/1115 - (26%)

  Fly   123 VAVRVRPLN------------ALECTRGQVTNVVQVHGNSNELTVQAGSSADASAGVTHFFSYDQ 175
            |.||.||:|            .::|.|||.  .:|..|.::|...|              |::|.
  Rat     8 VVVRCRPMNKRERELNCQSVVTVDCARGQC--FIQNPGAADEPPKQ--------------FTFDG 56

  Fly   176 VYYSCDPERKNFACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMGIEALDDAALDG 240
            .||.     ::|..|  ::...|.||::...||||..:|||||||||||::|.|:.
  Rat    57 AYYI-----EHFTEQ--IYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLP--------- 105

  Fly   241 GPPHDEAGIIPRFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTPI 305
             .|..:.|||||....:|   |:|:..:..:..|..||.|||||.:.|||         |..|
  Rat   106 -DPPCQRGIIPRAFEHVF---ESVQCAENTKFLVRASYLEIYNEDVRDLL---------GADT-- 155

  Fly   306 QQQQQQQRPALKVREHPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHSI 370
                 :||  |:::|||..|.||..||.|:|.:.:.....:..|...||...|.||..|||||||
  Rat   156 -----KQR--LELKEHPEKGVYVKGLSMHTVHNVAQCERVMETGWKNRAVGYTLMNKDSSRSHSI 213

  Fly   371 F--NIVLNLTDLSSDDGLSSDTDSSTASSLRQTRRSKISLVDLAGSERISVSGSNGERIREGVSI 433
            |  ||.:...|....|.|               |..|::|||||||||.|.:|:.|||::|...|
  Rat   214 FTINIEIYAVDERGKDHL---------------RAGKLNLVDLAGSERQSKTGATGERLKEATKI 263

  Fly   434 NKSLLTLGKVIAALADSRKAIANGPLGSGTPSTFVPYRESVLTWLLRENLGGNSKTVMLATISPA 498
            |.||..||.||:||.|.|             ...:|||:|.||.||:::||||:||:|:|.:|||
  Rat   264 NLSLSALGNVISALVDGR-------------CKHIPYRDSKLTRLLQDSLGGNTKTLMVACLSPA 315

  Fly   499 SIHADETLATLRYACKARSIVNRVKVNESPHDKIIRDLRAEVDRLKSLRNEYERQRRLSGNSNNP 563
            ..:.||||:|||||.:|::|.|:.::||.|.|.::|:.:.|:.|||::..:......||...:..
  Rat   316 DNNYDETLSTLRYANRAKNIKNKPRINEDPKDALLREYQEEIKRLKAILAQQMGPGNLSALLSTQ 380

  Fly   564 VP-------RKIIIETSVDETEVEALRQQLAER-ERELSRAQKSWMEKLKEAEDQRKSELR---V 617
            .|       .|:...|:|.: :.||.:|.:.|. |..|:|.:..:     |||.:.:..|:   .
  Rat   381 TPSGPVHPEEKLPSPTTVQQ-DTEAEKQMIREEYEERLARLKADY-----EAEQESRVRLQEDIT 439

  Fly   618 LKRRGLALELTAEQKQACLVNLTADPILSGTLFYLLPQGLVRIGRGRLPGGS---SSSQPDIVLD 679
            ..|....::|:..|:     ||..:. .:|.|               .||.:   :|..|.....
  Rat   440 AMRNSYDVKLSTLQE-----NLRKEK-ETGAL---------------CPGAAWEPTSCVPYTWAK 483

  Fly   680 GPL---VALQHCSIEHERGGKLYVIPGSE-----DFETYVNGELLKDRRQLFHGDRLVIGGSHYF 736
            |||   |.......:.|...:..|..|.|     .:||.|...:|.....|..|:        ..
  Rat   484 GPLHEAVLKAEVLCKTEVMSRAEVTSGPEYSPPLQYETAVKPTVLSMPDMLPRGE--------VT 540

  Fly   737 RISNPFCSQRGKADHPVDFQLAHQEILQKQEQQLRSELEAEKRAALTKIEQERAQHARDFEERLQ 801
            |...|..|:.      .:.:.:..|:.:..|.              :.:|......|....|.|.
  Rat   541 RSQAPLTSEE------PNMEPSRSEVFESNES--------------SNLEDSSMSEAYPGPEELS 585

  Fly   802 CLE------LEQFKYKCNSEMLETERQALALAQQQEHT--------PLRHEDAVSTPAQKSTILE 852
            .:|      |.:.:| ...|.|..|.....|  :.||:        |||...::..|.  :.:..
  Rat   586 NVEFSMPGVLAESRY-FPDEYLNPEAAGCPL--EAEHSVQDEPTLEPLRILASLQDPF--AEVEA 645

  Fly   853 DIQRIMLNPSEESLHKTQLMVKEATQRCRQLDLPLEFRQTQTPDEFGLLRTVILILDKQRGLKAE 917
            .:.|:....:...|.:| ::.:...|:....||   ...:.|..|..:...|:|..:....:|..
  Rat   646 KLARLSSTVAMTDLSQT-VVPQVPQQQPSSTDL---LEPSDTKSEVDVADNVLLRTEPDLSMKVA 706

  Fly   918 WPT---ARLGVWLD---------LVRDNAEQQEKLNATTIFQ---SVEVDWEPLDADLNETLSDT 967
            ...   |..|||::         .|.:.|:.|..|...::.:   .|||      |.|.|.|...
  Rat   707 EEVVSEAETGVWMESEAHVAHVAQVSEEAQPQPLLAMASVRRESIGVEV------AVLTEELQPV 765

  Fly   968 HNSSRIALNLSAMKDVLL------NKPLKR-------------------------------LLNA 995
             :..::...|..::..::      ||.||.                               |||.
  Rat   766 -DQQQVLARLQLLEQQVVGGEQAKNKDLKEKHRRRKRYADERKKQLVAALQNSDEDSGDWVLLNV 829

  Fly   996 SSSKSNTPRQTSTPSPGSQLVHFTKRLLTYDPEEIPESQSSF--------TTLVQQE------LQ 1046
            ..|.....|..      |:|:...::.|.....||.:.||.|        .|:.:||      .|
  Rat   830 YDSIQEEVRAK------SKLLEKMQKKLRAAEVEIKDLQSEFQLEKIDYLATIRRQERDSMLFQQ 888

  Fly  1047 IMQRSAQRLRRHCEAALLE---REN--HQDNGVLAVSLQEALARMDTVLNGMHTSLARAEATACV 1106
            ::::....:||.|..:.||   ||:  .:|||...:.        :.::  :.|||..|..|...
  Rat   889 LLEQVQPLIRRDCNYSNLEKIRRESSWDEDNGFWKIP--------EPII--LKTSLPVAVPTGTQ 943

  Fly  1107 TSPTKTQKAV 1116
            ..|.:...||
  Rat   944 NKPARKTSAV 953

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	154/415 (37%)
		SMC_N	514..>615	CDD:481474	28/108 (26%)
		FHA_KIF14	627..741	CDD:438759	25/124 (20%)
Kif17	XP_038967234.1	Motor_domain	4..335	CDD:473979	152/408 (37%)