Protein Alignment neb and sub

DIOPT Version :9

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: NP_001286548.1
• Gene: sub / 44870
• FlyBaseID: FBgn0003545
• Length: 628
• Species: Drosophila melanogaster
• Alignment Length: 724
• Identity: 161/724 - (22%)
• Similarity: 272/724 - (37%)
• Gaps: 259/724 - (35%)

  Fly    25 PASEMRKKVLMTR--AEDREHRDRPEQLLN-------------TAFSGSTPQPKPKPTALNACYT 74
            |..|:| ..||.|  :.||..|.||.:.:.             :.:|.:..:.|
  Fly    10 PRREVR-SFLMARDPSIDRRFRPRPNKKMRLFDNIQESEEESFSEYSDTESEYK----------- 62

  Fly    75 PSSLYRNANSTPGRAKTPGTGKSSCSRTKERDSLMES----------------CLSVSEESNMIV 123
                |:::.:|.|         :||:.:....|.:|:                ...||||:|:::
  Fly    63 ----YQSSEATEG---------ASCATSAADSSNVETGPQVFLRLRPVKDASKAYIVSEEANVLI 114

  Fly   124 AVRVRPLNALECTRGQVTNVVQVHGNSNELTVQAG--SSADASAGVTHFFSYDQVYYSCDPERKN 186
            .         .|.....:|      |.|.:....|  |..|::.|
  Fly   115 T---------SCKVDSTSN------NVNRMEKHFGFTSIFDSTVG-------------------- 144

  Fly   187 FACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMGIEALDDAALDGGPPHDEAGIIP 251
               |..:::....|.|   .|.....:..||.:||||:|:::|    ||.         .|||||
  Fly   145 ---QRDIYDTCVGPKI---MEEECVTIMTYGTSGSGKTYTLLG----DDV---------RAGIIP 190

  Fly   252 RFCHELF-------------------------------------------------RRIEAV--- 264
            |....:|                                                 :|::.|
  Fly   191 RALENIFTIYQDTVFRSPKLKLINGSIVFLQDDASLKELQIRKKLLDLCPDISAHHQRLKQVIDG 255

  Fly   265 ------KSQQQLQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTPIQQQQQQQRPALKV---RE 320
                  |:...:.|.|.||:.|||||.::|||::.......|| .|        |..||:   :.
  Fly   256 DHMFETKASTDVSVLVWVSFVEIYNELVYDLLAIPPKQDKLGE-VP--------RKNLKIVGNKG 311

  Fly   321 HPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHSIFNIVLNLTDLSSDDG 385
            |    .::..|::..|.|.......|.:|..:...|||::|..|||||.:|.:
  Fly   312 H----VFIKGLTSVFVTSSEEALRLLRLGQQRSTYASTSVNANSSRSHCVFTV------------ 360

  Fly   386 LSSDTDSSTASSLRQTRRSKISLVDLAGSERISVSGSNGERIREGVSINKSLLTLGKVIAALADS 450
               |......|.:  |.:|.....|||||||::.:|::|.|::|..:||.||:.||:.:.|.:..
  Fly   361 ---DILKYNRSGI--TTQSSYKFCDLAGSERVNNTGTSGLRLKEAKNINTSLMVLGRCLDAASTV 420

  Fly   451 RKAIANGPLGSGTPSTFVPYRESVLTWLLRENLGGNSKTVMLATISPASIHADETLATLRYACKA 515
            :|.         ..:..:|||:|.||.||:..|.|..|..|:.|::|...:.:|.|..|.:|..|
  Fly   421 QKK---------KNADIIPYRDSKLTMLLQAALLGKEKLAMIVTVTPLDKYYEENLNVLNFASIA 476

  Fly   516 RSIVNRVKV-------------------------NESPHDKIIRDLRAEVDRLK-------SLRN 548
            ::|:.:..|                         .:...|:.:| |:.|:::||       .|..
  Fly   477 KNIIFKEPVIKQHRVSYCGFMEFSKMSTCEGGDYTKELEDENVR-LQLEIEQLKYDHVLQMQLLE 540

  Fly   549 EYERQRRLSGNSNNPVPRKIIIETSVDETEVEALRQQL-AERERE--LSRAQKSWMEKLKEAEDQ 610
            | :.:|.|:.....      ||:.:..:.|.|..::.| |:||.|  ||..::.:.|::::.:|
  Fly   541 E-KLRRELTATYQE------IIQNNKKQYEDECEKKLLIAQRESEFMLSSQRRRYEEQIEDLKD- 597

  Fly   611 RKSELRVLK 619
               |:..||
  Fly   598 ---EIEELK 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	111/493 (23%)
		KISc	120..525	CDD:214526	111/492 (23%)
		Kinesin_assoc	524..657	CDD:292801	27/131 (21%)
		FHA	634..740	CDD:238017
sub	NP_001286548.1	KISc	89..477	CDD:276812	112/480 (23%)
		Kinesin	93..479	CDD:278646	113/478 (24%)
		GBP_C	<512..603	CDD:303769	24/102 (24%)
		coiled coil	576..586	CDD:293879	4/9 (44%)
		coiled coil	592..603	CDD:293879	2/14 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437854
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030