Protein Alignment neb and Klp67A

DIOPT Version :9

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: NP_001286999.1
• Gene: Klp67A / 39068
• FlyBaseID: FBgn0004379
• Length: 814
• Species: Drosophila melanogaster
• Alignment Length: 1074
• Identity: 256/1074 - (23%)
• Similarity: 402/1074 - (37%)
• Gaps: 340/1074 - (31%)

  Fly   117 EESNMIVAVRVRPLNALECTRGQVTNVVQVHGNSNELTVQAGSSADASAGVTHFF---------- 171
            :.:|:.|||||||.|..|..:.| .::::|...|..|       .|.......||
  Fly     5 QHTNIKVAVRVRPYNVRELEQKQ-RSIIKVMDRSALL-------FDPDEEDDEFFFQGAKQPYRD 61

  Fly   172 -----------SYDQVYYSCDPERKNFACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSY 225
                       .:|:|:   |.:..|    ..:||....||:|....|||..:|.||.||:||::
  Fly    62 ITKRMNKKLTMEFDRVF---DIDNSN----QDLFEECTAPLVDAVLNGYNCSVFVYGATGAGKTF 119

  Fly   226 SMMGIEALDDAALDGGPPHDEAGIIPRFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEKIHDLL 290
            :|:|.||             ..|:......:||.:|:|....::.  :|.|||.|:|||.:.:||
  Fly   120 TMLGSEA-------------HPGLTYLTMQDLFDKIQAQSDVRKF--DVGVSYLEVYNEHVMNLL 169

  Fly   291 SVQHAAAATGESTPIQQQQQQQRPALKVREHPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRAT 355
            :         :|.|           ||:||.. .|..|..|....:.|...|...|.:|||.|..
  Fly   170 T---------KSGP-----------LKLREDN-NGVVVSGLCLTPIYSAEELLRMLMLGNSHRTQ 213

  Fly   356 ASTAMNDKSSRSHSIFNIVLNLTDLSSDDGLSSDTDSSTASSLRQTRRS-KISLVDLAGSERISV 419
            ..|..|.:|||||:||.:.:.:|:..:|                 |:|: |:|::|||||||.:.
  Fly   214 HPTDANAESSRSHAIFQVHIRITERKTD-----------------TKRTVKLSMIDLAGSERAAS 261

  Fly   420 SGSNGERIREGVSINKSLLTLGKVIAALADSRKAIANGPLGSGTPSTFVPYRESVLTWLLRENLG 484
            :...|.|.:||.|||||||.||..|..|||..|              .:|||:|.||.:|:::||
  Fly   262 TKGIGVRFKEGASINKSLLALGNCINKLADGLK--------------HIPYRDSNLTRILKDSLG 312

  Fly   485 GNSKTVMLATISPASIHADETLATLRYACKARSIVNRVKVN----ESPHD---KIIRDLRAEVDR 542
            ||.:|:|:|.:|.:|:..::|..||:||.:|:.|...:|.|    :.|.:   |.|.::.||.:|
  Fly   313 GNCRTLMVANVSMSSLTYEDTYNTLKYASRAKKIRTTLKQNVLKSKMPTEFYVKKIDEVVAENER 377

  Fly   543 LKSLRNEYE---RQRRLSGNSN-NPVPRKIIIETSVDETEVEALRQQLAERERELSRAQK----S 599
            ||......|   .|...:|||. :|:..|... :.:|  .|.|..:||  :|..|....|    :
  Fly   378 LKERNKALEAKATQLERAGNSGFDPLELKTWY-SKID--AVYAAARQL--QEHVLGMRSKIKNIN 437

  Fly   600 WMEKL-KEAEDQRKSELRVLKRRGLALELTAEQKQACLVNLTADPILSGTLFYLLPQGLVRIGRG 663
            :.:.| ||.|:.||              |....::.|
  Fly   438 YRQTLKKELEEFRK--------------LMCVDQRVC---------------------------- 460

  Fly   664 RLPGGSSSSQPDIVLDGPLVALQHCSIEHERGGKLYVIPGSEDFETYVNGELLKDRRQLFHGDRL 728
                                                    .|||..:.|
  Fly   461 ----------------------------------------QEDFRRFAN---------------- 469

  Fly   729 VIGGSHYFRISNPFCSQRGKADHPVDFQLAHQEILQKQEQQLRSELEAEKRAALTKIEQERAQHA 793
                     ..:...||..|....:...|:..||..:       :||:.||    ::.:.:|...
  Fly   470 ---------YMSTLTSQMEKYKEELPSWLSKMEIAYQ-------DLESLKR----EVNKSKAYQI 514

  Fly   794 RDFEERLQCLELEQFKYK--------CNSEMLETERQALALAQQQEHTPLRHEDAVSTPAQKSTI 850
            .....:.:.|||:..|..        .|.|::|.    |.|.::...|      |.....|....
  Fly   515 LIVYVKYKDLELQLTKQNIFNNHVNAINQELVEN----LDLMRKSFRT------ACEVLNQTYDR 569

  Fly   851 LEDIQRIMLNPS-----EESLHKTQLMVKEATQRCRQLD---LPLEFRQTQTPDEFGLLRTVILI 907
            |||.|:  |.|.     |..|.|.:....||..:..:::   :|:..|.:...:
  Fly   570 LEDGQK--LTPEIEAVFERLLRKMRFADSEANTKMAEMNPLAVPVALRSSAQEE----------- 621

  Fly   908 LDKQRGLKAEWPTARLGVWLDLVRDNAEQQEKLNATT---IFQSVEVDWEPLDADLNETLSDTHN 969
                     |.||..|..       :|:::::..|.:   :..|:|      |.|..:|.||:..
  Fly   622 ---------EEPTCSLTA-------SAKKRQRQAAQSDDDLHLSME------DFDSQDTESDSEE 664

  Fly   970 SSRIALNLSAMKDVLLNKPLKRLLNASSSKSNTPRQTSTPSPGSQLVHFTKRLLTYDPEEIPESQ 1034
            ..|.......:.:..:..|.....::|:|.|::.|:..|.:       .||      |..:  .|
  Fly   665 LHRTFKRPRNLNETQVLGPCSSSSSSSTSSSSSARKALTAT-------VTK------PRTV--QQ 714

  Fly  1035 SSFTTLVQQE-------------LQIMQRSAQRLRRHCEAALLERENHQDNGVLAVSLQEALARM 1086
            ...:.|:..:             |:....:||.|:|...||.|.:||.:.|.........||  |
  Fly   715 RLVSDLISDQNVRGGNEKIKKALLKSNHFTAQGLQRTLAAASLAKENVKYNANYVRKSPRAL--M 777

  Fly  1087 DTVLNGMHTSLARAEATACVTSP--TKTQKAVRF 1118
            ...|.|..| |||....:....|  .|..:|..|
  Fly   778 AKALAGTST-LARKPLGSASKEPPLVKFNRAASF 810

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	135/427 (32%)
		KISc	120..525	CDD:214526	135/426 (32%)
		Kinesin_assoc	524..657	CDD:292801	32/148 (22%)
		FHA	634..740	CDD:238017	5/105 (5%)
Klp67A	NP_001286999.1	KISc	8..353	CDD:214526	135/426 (32%)
		KISc_KIP3_like	8..346	CDD:276821	133/419 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437994
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030