Protein Alignment neb and Klp64D

DIOPT Version :9

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Alignment Length: 923
• Identity: 244/923 - (26%)
• Similarity: 364/923 - (39%)
• Gaps: 296/923 - (32%)

  Fly   117 EESNMIVAVRVRPLNALECTRGQVTNVVQVHGNSNELTVQAGSSADASAGVTHFFSYDQVYYSCD 181
            |..|:.|.||.||::..|.:.|.: :.:.|...:..:||...::.......|::|  |.|:
  Fly    17 EIENVRVVVRTRPMDKNELSAGAL-SAISVDKINRAITVMKPNATANEPPKTYYF--DNVF---- 74

  Fly   182 PERKNFACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMGIEALDDAALDGGPPHDE 246
               ...:.|..::..||||::|...||||..:.||||||:||:|:|           .|.|...:
  Fly    75 ---DGGSNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTM-----------SGNPDSPQ 125

  Fly   247 A-GIIPRFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTPIQQQQQ 310
            . ||||.....:|..|...|..|:..  |.|||.|||||::.|||...     .|:|
  Fly   126 TKGIIPNAFAHIFGHIAKAKENQKFL--VRVSYMEIYNEEVRDLLGKD-----VGKS-------- 175

  Fly   311 QQRPALKVREHPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHSIFNIVL 375
                 |:|:|.|..|.:|.|||.:.|.:...|.|.:.:||..||..:|.||.:|||||:||:|.:
  Fly   176 -----LEVKERPDIGVFVKDLSGYVVHNADDLENIMRLGNKNRAVGATKMNQESSRSHAIFSITV 235

  Fly   376 NLTDLSSDDGLSSDTDSSTASSLRQTRRSKISLVDLAGSERISVSGSNGERIREGVSINKSLLTL 440
            ..::|...|             ::..|..|:.|||||||||.|.:.::|:|::|...||.||..|
  Fly   236 ERSELGEGD-------------VQHVRMGKLQLVDLAGSERQSKTQASGQRLKEATKINLSLSVL 287

  Fly   441 GKVIAALADSRKAIANGPLGSGTPSTFVPYRESVLTWLLRENLGGNSKTVMLATISPASIHADET 505
            |.||:||.|.:             ||.:|||.|.||.||:::|||||||||.||||||..:..||
  Fly   288 GNVISALVDGK-------------STHIPYRNSKLTRLLQDSLGGNSKTVMCATISPADSNYMET 339

  Fly   506 LATLRYACKARSIVNRVKVNESPHDKIIRDLRAEVDRLKSLRNEYERQRRLSGNSNNPVPRKIII 570
            ::|||||.:|::|.||:.:||.|.|.::|..:.|:.||:....|        |:|....|.....
  Fly   340 ISTLRYASRAKNIQNRMHINEEPKDALLRHFQEEIARLRKQLEE--------GDSLEEEPPSSEE 396

  Fly   571 ETSVDETEVEALRQQLAERERELSRAQKSWMEKLKEAEDQRKSELRVLKRRGLALELTAEQKQAC 635
            |....:.|:||..:  .|.|....:|.:...:|.:|..|..|.||  .||:      ...||:
  Fly   397 EEDTADDELEAPLE--IELESSTIQAVEKKPKKKREKTDAEKEEL--AKRK------NEHQKE-- 449

  Fly   636 LVNLTADPILSGTLFYLLPQGLVRIGRGRLPGGSSSSQPDIVLDGPLVALQHCSIEHER-GGKLY 699
                                                             ::|...|.|. ..||.
  Fly   450 -------------------------------------------------IEHAKTEQETLRNKLV 465

  Fly   700 VIPGSEDFETYVNGELLKDRRQLFHGDRLVIGGSHYFRISNPFCSQRGKADHPVDFQLAHQEILQ 764
            .:.|    :..|.||.|.::.|.                                     ||:|.
  Fly   466 SLEG----KILVGGENLLEKAQT-------------------------------------QELLL 489

  Fly   765 KQEQQLRSELEAEKRA--ALTKIEQERAQHARDFEERLQCLE------------LEQFKYKCNSE 815
            :|.   .:|||..:::  ||.:..|::|....|.|||...|:            :.|......||
  Fly   490 EQS---IAELEQHEKSEEALKQTLQQKATERIDIEERYSTLQDASTGITKKIHRVMQMLMGVKSE 551

  Fly   816 MLETERQALALAQQQEHTPLRHEDAVSTPAQKSTILEDIQRIMLNPSEESLHKTQLMVKEATQRC 880
            :.:         |||||           ..:|..|.|:|:.:                      .
  Fly   552 LAD---------QQQEH-----------QREKEGIYENIRSL----------------------S 574

  Fly   881 RQLDLPLEFRQTQTPDEFGLLRTVILILDKQRGLKAEWPTARLGVWLDLVRDNAEQQEKLNATTI 945
            |:|.|......:..|.|:                                      |..:|..|.
  Fly   575 RELALCELVLNSYVPKEY--------------------------------------QSMINQYTH 601

  Fly   946 FQSVEVDWEPLDADLNETLSDTHNSSRIALNLSAMK------------DVLLNKPLKRLLNASSS 998
            :.....:|:      .:.::.|.|:.|  .::||.|            .|.|:.....:.|...|
  Fly   602 WNEDIGEWQ------LKCVAYTGNNMR--KHISAHKTSGKEPDFLDLSHVYLSYNTDGVSNPMRS 658

  Fly   999 KSNTPRQTSTPSP 1011
            ||..||.:..|.|
  Fly   659 KSARPRTSGVPRP 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	150/406 (37%)
		KISc	120..525	CDD:214526	150/405 (37%)
		Kinesin_assoc	524..657	CDD:292801	29/132 (22%)
		FHA	634..740	CDD:238017	11/106 (10%)
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	147/399 (37%)
		Kinesin	26..352	CDD:278646	144/392 (37%)
		RILP-like	<437..556	CDD:304877	36/230 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437779
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940