Protein Alignment neb and Kif28

DIOPT Version :9

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: NP_001357826.1
• Gene: Kif28 / 383592
• MGIID: 2686151
• Length: 1033
• Species: Mus musculus
• Alignment Length: 1004
• Identity: 283/1004 - (28%)
• Similarity: 420/1004 - (41%)
• Gaps: 283/1004 - (28%)

  Fly   115 VSEESNMIVAVRVRPLNALECTRGQVTNVVQVH-GN------SNELTVQAGSSADASAGVTHFFS 172
            |....::.|||||||.:..|...|... |:.:| ||      .||..|:.             |:
Mouse    11 VPRSDSVRVAVRVRPFSQREKNSGSQC-VISMHSGNISIRDPKNEERVKT-------------FT 61

  Fly   173 YDQVYYSCDPERKN-------------FACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKS 224
            :|..|:|.|..:|:             ||.|:.||....|.::|:|:.||||.|.||||||||||
Mouse    62 FDLTYWSHDGFQKDEDGVLIPSDPASKFAGQSDVFHDIGRGILDSAWRGYNATLLAYGQTGSGKS 126

  Fly   225 YSMMGIEALDDAALDGGPPHDEAGIIPRFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEKIHDL 289
            |||:|...             ..|:|||.|.|||:.||  |.::.|:.:|..|..|||||:|.||
Mouse   127 YSMIGFGT-------------NKGLIPRVCEELFQAIE--KQKENLEPQVMFSMLEIYNEQIRDL 176

  Fly   290 LSVQHAAAATGESTPIQQQQQQQRPALKVREHPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRA 354
            ||...|..                 .|:|||....|.:|..|.....::|:.:...:..|:..|.
Mouse   177 LSRTKAPG-----------------GLRVREDQQLGFFVEGLKWVPCENYAQIEKLVEQGSKIRM 224

  Fly   355 TASTAMNDKSSRSHSIFNIVLNLTDLSSDDGLSSDTDSSTASSLRQTRRSKISLVDLAGSERISV 419
            ||||.||..|||||.:  |.:....:..|..|              |:||.|::||||||||...
Mouse   225 TASTNMNASSSRSHML--IAIQFKQVFLDTAL--------------TKRSSINMVDLAGSERQRS 273

  Fly   420 SGSNGERIREGVSINKSLLTLGKVIAALADSRKAIANGPLGSGTPSTFVPYRESVLTWLLRENLG 484
            |||.|:|:|||..:|.||.:||.||:||||         |..|.....:|||:||||.||:..||
Mouse   274 SGSEGDRLREGSRVNLSLTSLGNVISALAD---------LAMGKKVLHIPYRDSVLTKLLQSALG 329

  Fly   485 GNSKTVMLATISPASIHADETLATLRYACKARSIVNRVKVNESPHDKIIRDLRAEVDRLKSLRNE 549
            |||:|.::|.:|||.|..:|||:|||||.:|:.:.||..:|..|   :.|..|||...|...|.
Mouse   330 GNSRTTLIAALSPADICYEETLSTLRYAERAKKVRNRAVINTCP---LARASRAENALLLGFRG- 390

  Fly   550 YERQRRLSGNSNNPVPRKIIIETSVDETEVEALRQQLAER---ERELSRAQKSWMEKLKEAEDQR 611
                   :|.:.:|.              .....|||..:   .:.|.:|::.|.|:. ||..|.
Mouse   391 -------AGAAEHPA--------------CFWAEQQLGNQGTWAQLLEQARREWEEQY-EALTQE 433

  Fly   612 KSELRVLKRRGLALELTAEQKQACLVNLTADPILSGTLFYLLPQGLVRIGRGRLPGGSSSSQPDI 676
            :..:|:|..               |:|:..||.|:|.|.:.:..|...:||        ::...|
Mouse   434 QKMVRILPH---------------LLNVNEDPQLTGVLKFFIHNGSCDVGR--------AASNAI 475

  Fly   677 VLDGPLVALQHCSIEHERGGKLYVIPGSEDFETYVNGELLKDRRQLFHGDRLVIGGSHYFRISNP 741
            .|.|..::.:|.|..: ..||:.|.|.|: .:..|||..:..|.:|.|.||:::|.:..| :...
Mouse   476 CLQGLGISDKHASFVN-LDGKVTVAPHSK-CKVIVNGVPVTGRTKLQHLDRIILGSNSAF-LYVG 537

  Fly   742 FCSQRGKAD-HPVDFQLAHQEILQKQEQQLRSELEAEKRAALTKI----EQERAQHARDFEE--R 799
            |.|:||..| ...|:.....|         |:..|....|.|..:    :|........|::  :
Mouse   538 FPSERGAEDLSRFDYDFFQLE---------RAAAEGVSVATLGCVSPGDDQADPSILAVFQDYVK 593

  Fly   800 LQCLELEQFKYKCNSEMLETERQALALAQQQEHTPLRHEDAVSTPAQKSTILEDIQR-IMLNPSE 863
            |..|.:|.      ::|.|..::.|.:           |..|...|...:...|:|: :|:..::
Mouse   594 LMPLVVEA------NQMSEELKKGLTM-----------ELKVKNLASSDSRGYDLQKEVMVKVTK 641

  Fly   864 ESLHKT-----------QLMVKEATQRCRQLDLPLEFRQT---QTPDEFGLLRTVILILDKQRGL 914
            :..|:.           :.:::|..||.      ||.|.:   |..|.|
Mouse   642 QGTHEVWIWSKAKFINRKFLMEELYQRF------LESRDSHVAQEDDPF---------------- 684

  Fly   915 KAEW---PTARLG---VWLDLVRD---NAEQQEKLNATTIFQSV----------------EVDW- 953
               |   ....||   |||..:..   ..||.|.||...:.::|                |.|.
Mouse   685 ---WDPLEVVHLGSAHVWLQPLAHCMMLEEQVEFLNCDGLEEAVLHIRITPCSPEGWAHGEEDMV 746

  Fly   954 -EPLDADLNETLS-DTH------------NSSR---IALNLSAMKDVLLNKPLKRLLNASSSKSN 1001
             :||:. |.:.:. .||            :.||   :...:..:.:.|..||:.:.:|
Mouse   747 IDPLEL-LGKRIDFQTHIVRCLGVKWLKEDGSRGIQMGYKIYDLPNTLYTKPVWKSVN------- 803

  Fly  1002 TPRQTSTPSPGSQLVHF-----TKRLLTY 1025
             ||...|       |||     ::..|.|
Mouse   804 -PRIEET-------VHFAALGASREFLDY 824

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	162/425 (38%)
		KISc	120..525	CDD:214526	162/424 (38%)
		Kinesin_assoc	524..657	CDD:292801	29/135 (21%)
		FHA	634..740	CDD:238017	30/105 (29%)
Kif28	NP_001357826.1	Motor_domain	15..370	CDD:354959	162/425 (38%)
		FHA	440..537	CDD:238017	31/122 (25%)
		KIF1B	655..693	CDD:372100	10/62 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123768at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820