Protein Alignment neb and Klp59D

DIOPT Version :10

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: NP_611762.1
• Gene: Klp59D / 37674
• FlyBaseID: FBgn0034827
• Length: 729
• Species: Drosophila melanogaster
• Alignment Length: 783
• Identity: 192/783 - (24%)
• Similarity: 291/783 - (37%)
• Gaps: 265/783 - (33%)

  Fly    38 AEDREHRDRPEQLLNTAFSGSTPQPKPK--------------------------PTALNA----- 71
            ||::....:|...|.....||:|...||                          |.|:.|
  Fly    63 AENQPPISKPPSSLLPKPRGSSPTGGPKTHTGNPYAERMRVQDGRSKIATRKTDPAAVGAGNHEL 127

  Fly    72 --CYTP----SSLYRNANSTPGRAKTPGTGKSS------------------------CSRTKERD 106
              .:||    ....|:|:.|.|| |:.|...|:                        ..:.:|:|
  Fly   128 GRAHTPRVPAGRPDRDASPTQGR-KSQGGNNSNQRFSSVVREVNRMKEQREKRRARQAEQLQEKD 191

  Fly   107 SLMESCLSVSEESNMIVAVRVR---------PLNALECTRGQVTNVV---------QVHGNSNEL 153
            :|..   :.....|..|:|.:|         ||..|:...|.|..:.         :...||..|
  Fly   192 ALRR---NNPGNPNWEVSVMLRQYRSTLIFSPLRCLDPNGGTVQQITVCVRKRPMSRKEENSKNL 253

  Fly   154 TVQAGSSADA--------SAGVT-----HFFSYDQVYYSCDPERKNFACQAKVFEGTARPLIDTA 205
            .:....|||:        ...:|     |.|.:|   |:.|.|..|    |.|::.||||||.|.
  Fly   254 DIITVPSADSLIVHELRLKVDLTKFLEHHKFRFD---YTFDEECSN----ALVYDHTARPLIRTM 311

  Fly   206 FEGYNACLFAYGQTGSGKSYSMMG--IEALDDAALDGGPPHDEAGIIPRFCHELFRRIEAVKSQQ 268
            |||.||..||||||||||:::|.|  ...:.|..         .||......::|..:.. ...:
  Fly   312 FEGGNATCFAYGQTGSGKTHTMGGEFFGKVQDCG---------TGIYAMAARDVFEEVSR-PEYR 366

  Fly   269 QLQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTPIQQQQQQQRPALKVREHPIFGPYVVDLSA 333
            |:..::..|:||||..|:.|||                   ...:|.|:|.|.......||.|:.
  Fly   367 QMGAKITCSFFEIYGTKVFDLL-------------------LPNKPMLRVLEDARQQVVVVGLTE 412

  Fly   334 HSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHSIFNIVLNLTDLSSDDGLSSDTDSSTASSL 398
            ..|.....:...:..|:.:|.:..|:.|.||||||::|.|.|:..|.....|
  Fly   413 MPVTKVEDVLRLIEHGSKERTSGQTSANAKSSRSHAVFQIALHFPDSWGPHG------------- 464

  Fly   399 RQTRRSKISLVDLAGSERISVSGSNGERIR-EGVSINKSLLTLGKVIAALADSRKAIANGPLGSG 462
                  |.|.|||||:||.:.:.|...:.| ||..||||||.|.:.|.||  ||:
  Fly   465 ------KCSFVDLAGNERGADTQSADRQTRIEGAEINKSLLALKECIRAL--SRQ---------- 511

  Fly   463 TPSTFVPYRESVLTWLLRENL--GGNSKTVMLATISPASIHADETLATLRYACKARSIVNRVKVN 525
              |:.:|:|.|.||.:||::.  |..:||.|:|.|||:....:.||.|||||.:.:.::.:
  Fly   512 --SSHLPFRGSKLTQVLRDSFVGGKKNKTCMIAMISPSMSCVENTLNTLRYADRVKELIAK---- 570

  Fly   526 ESPHDKIIRDLRAEVDRLKSLRNEYERQRRLSGNSNNPVPRKIIIETSVDETEVEALRQQLAERE 590
                         |.:.|:|:..:.|:...|:                 :|:|.|    .:|:.|
  Fly   571 -------------EDEHLQSVEGDGEKSPDLN-----------------EESEPE----MMADEE 601

  Fly   591 RELSRAQKSWMEKLKEAEDQRKSELRVLKRRGLALELTAEQKQACLVNLTADPILSGTLFYLLPQ 655
            .:            :|.||:....|.:           :.::.:...|::.|...:.||..|.|.
  Fly   602 GD------------EEPEDEDNQHLTI-----------SSEEASSYNNMSYDMSFNHTLNILGPS 643

  Fly   656 GLVRIGRGRLPGGSSSSQPDIVLDGPLVALQHCSIEHERGGKLYVIPGSEDFETYV-NGELLKDR 719
            ..|.|..                    ||.||..:             .|:.|||. |...||..
  Fly   644 RNVDIQE--------------------VAEQHALL-------------VENLETYAHNFRQLKTD 675

  Fly   720 RQL 722
            :::
  Fly   676 KEI 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	134/441 (30%)
		SMC_N	514..>615	CDD:481474	13/100 (13%)
		FHA_KIF14	627..741	CDD:438759	19/97 (20%)
Klp59D	NP_611762.1	KISc_KIF2_like	233..565	CDD:276818	125/400 (31%)