Protein Alignment neb and klp-20

DIOPT Version :9

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: NP_497178.1
• Gene: klp-20 / 3565057
• WormBaseID: WBGene00002230
• Length: 646
• Species: Caenorhabditis elegans
• Alignment Length: 745
• Identity: 214/745 - (28%)
• Similarity: 327/745 - (43%)
• Gaps: 213/745 - (28%)

  Fly   123 VAVRVRPLNALECTRGQVTNVVQVHGNSNELTVQAGSSADASAGVTHFFSYDQVYYSCDPERKNF 187
            |.||.||::..|..:|   :.:.|..|..|..|...|.:......|.:|  |.|:   .|...
 Worm     9 VVVRCRPISTTEKLQG---HKIAVTCNDEEKAVNIKSLSQEDPPRTFYF--DAVF---SPNTD-- 63

  Fly   188 ACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMG-IEALDDAALDGGPPHDEAGIIP 251
              |..|:...|||:::...:|||..:|||||||:||:::|.| :|           |.:..||||
 Worm    64 --QMTVYNVAARPIVENVLKGYNGTIFAYGQTGTGKTFTMAGDLE-----------PVEMRGIIP 115

  Fly   252 RFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTPIQQQQQQQRPAL 316
            .....:|..|  .|.|......|.|||.|||||:|.||||..|    .|.              |
 Worm   116 NSFAHIFDHI--AKCQHDTTFLVRVSYLEIYNEEIRDLLSKDH----NGN--------------L 160

  Fly   317 KVREHPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHSIFNIVLNLTDLS 381
            :::|.|..|.||.:||..:|::.|.::..:..|:..|...:||||.:|||||::|.:.:.    |
 Worm   161 EIKERPDVGVYVRNLSNPTVENASKMQALMEFGSKNRKVGATAMNLESSRSHAMFTVTIE----S 221

  Fly   382 SDDGLSSDTDSSTASSLRQTRRSKISLVDLAGSERISVSGSNGERIREGVSINKSLLTLGKVIAA 446
            ..:||              ..:.|:.|||||||||.|.:|:.|||::|...||.||.|||.||::
 Worm   222 CRNGL--------------VTQGKLQLVDLAGSERQSKTGAQGERLKEAAKINLSLSTLGNVISS 272

  Fly   447 LADSRKAIANGPLGSGTPSTFVPYRESVLTWLLRENLGGNSKTVMLATISPASIHADETLATLRY 511
            |.|.:             ||.:|||.|.||.||:::|||||||||:|.:.||:.:.||||:||||
 Worm   273 LVDGK-------------STHIPYRNSKLTRLLQDSLGGNSKTVMIANVGPATYNYDETLSTLRY 324

  Fly   512 ACKARSIVNRVKVNESPHDKIIRDLRAEVDRLKSLRNEYERQRRLSGNSNNPVPRKIIIETSVDE 576
            |.:|::|.|..|:||.|.|..:|..:.|::.|:.:.:|           .||         ..||
 Worm   325 ANRAKNIQNVAKINEDPKDAQLRKFQLEIEALRKILDE-----------ENP---------GDDE 369

  Fly   577 TEVEALRQQLAERERELSRAQKSWMEKLKEAEDQRKSELRVLKRRGLALELTAEQKQACLVNLTA 641
            .:.||...::.|||.|:.:.:|...|::..|.:..::. |::|.   .:|..||.|:|
 Worm   370 NQEEAWEAKMQEREVEMEKKRKILEERVNSAVNDEETH-RLVKE---MMENEAELKKA------- 423

  Fly   642 DPILSGTLFYLLPQGLVRIGRGRLPGGSSSSQPDIVLDGPLVALQHCSIEHERGGKLYVIPGSED 706
                                                           ..|||:
 Worm   424 -----------------------------------------------RSEHEK------------ 429

  Fly   707 FETYVNGELLKDRRQLFHGDRLVIGGSHYFRISNPFCSQRGKADHPVD-FQLAHQEILQK--QEQ 768
                :..:|.|..:      :|::||.:...          |.:.... .::.::|:.|.  ||.
 Worm   430 ----LRSKLEKIEK------KLIVGGENLLE----------KVEEQAKLLEVNNKELEQSKFQEA 474

  Fly   769 QLRSELEAEKRAALTKIE------QERA-----------QHARDFEERLQCLELEQFKYKCNSEM 816
            .||::|| |:.|...:||      ||.|           ...:|  .|.:..:||:...:....|
 Worm   475 HLRTQLE-ERTAVKVEIEERYSSLQEEAFVKSKKIKKVSNELKD--ARAELKDLEEDHQRQVEAM 536

  Fly   817 LETERQ-----ALALAQQQEHTPLRHEDAV 841
            |:..||     .|.:|...|:.|:.|.:.:
 Worm   537 LDDIRQLRKELLLNIAIIDEYIPVEHVELI 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	149/402 (37%)
		KISc	120..525	CDD:214526	149/402 (37%)
		Kinesin_assoc	524..657	CDD:292801	28/132 (21%)
		FHA	634..740	CDD:238017	9/105 (9%)
klp-20	NP_497178.1	Motor_domain	5..331	CDD:328930	146/395 (37%)
		SMC_N	<325..>569	CDD:330553	70/355 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910