Protein Alignment neb and CG14535

DIOPT Version :9

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: NP_001285726.1
• Gene: CG14535 / 34073
• FlyBaseID: FBgn0031955
• Length: 1131
• Species: Drosophila melanogaster
• Alignment Length: 1158
• Identity: 212/1158 - (18%)
• Similarity: 371/1158 - (32%)
• Gaps: 409/1158 - (35%)

  Fly    52 NTAFSGS---TPQPKPKPTAL-----NACYTPSSLYRNANSTPGRAKTPGTGKSSCS-RTKERDS 107
            |..|.|:   .|.|.| ||.:     ..||                   |.||.... |..:||.
  Fly    12 NGGFCGALQRAPPPMP-PTLIRRLSSRECY-------------------GVGKVKVMLRVADRDR 56

  Fly   108 LMESCLSVSEESNMIVAVRVRPLNALECTRGQVTNVVQVHGNSNELT--------VQAGSSADAS 164
                 .|...|.:.:         ||:..:.|||           ||        .||.......
  Fly    57 -----NSGGTEPDFM---------ALDKKKRQVT-----------LTDPRTACPPPQAAQERAPM 96

  Fly   165 AGVTHFFSYDQVYYSCDPERKNFACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMG 229
            ......|::|.::...|  :::..|.:.:.|     :|....||.:.||.|.|...:|::.:::|
  Fly    97 VAAPKMFAFDNLFTGED--KQSDVCASALSE-----VIPAVLEGSDGCLLAMGYPATGQAQTVLG 154

  Fly   230 IEALDDAALDGGPPHDEA---------GIIPRFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEK 285
                   .|.||.....|         |..|.....|::.|:..:.:...:..|.||...:...|
  Fly   155 -------ELGGGSGSGSASGSGVACSLGAAPCAIAWLYKGIQERRQKSGARFSVRVSAVGVSATK 212

  Fly   286 ----IHDLLSVQHAAAATGESTPIQQQQQQQRPALKVREHPIFGPYVVDLSAHSVDSYSALRNWL 346
                ..||| :.|||            :....|.:.:|:..:.||  .:|.|.:.:. :||....
  Fly   213 PDALSQDLL-ISHAA------------ESDDSPGIYLRDDFLGGP--TELRAPTAER-AALFLDS 261

  Fly   347 AVGNSQRATASTAMNDKSS----RSHSIFNIVLNLTDLSSDDGLSSDTDSSTASSLRQTRRSKIS 407
            |:....:::.|||......    .|..||.:.:....||...|::..             ||::.
  Fly   262 ALAGRLKSSGSTASGSSGCAAPLESALIFTLHVYQYSLSRKGGVAGG-------------RSRLH 313

  Fly   408 LVDLAGSERISVSGSNGERIREGVSINKSLLTLGKVIAALADSRKAIANGPLGSGTPSTFVPYRE 472
            ::||.|     .:..||.....|:         |.::.|:...::              ..|:::
  Fly   314 IIDLGG-----CANRNGGLPLSGI---------GNILLAILSGQR--------------HPPHKD 350

  Fly   473 SVLTWLLRENLGGNSKTVMLATISPASIHADETLATLRYACKARSIVNRVKVNESPHDKIIR-DL 536
            ..||.||::            .::|.:.|.              :||..|:..:|..|.:.. .:
  Fly   351 HPLTPLLKD------------CLAPITCHV--------------AIVAHVRPEQSYQDALSTIQI 389

  Fly   537 RAEVDRLKSLRNEYERQRR------------LSGNSN------NPVPRKIIIETSV------DET 577
            .:.:.||:      .|:.|            |.||.:      :|...:|..:|.:      |.|
  Fly   390 ASRIHRLR------RRKHRVPMPLAVGLAQGLGGNGSSAGSGADPSSSEISADTVIYMGPNDDAT 448

  Fly   578 EVE--------------------ALRQQLAERERELSRAQKSWMEKLKEAEDQRK----SELRVL 618
            :.|                    ||:....|:....|.:....|.|...|.::.|    |....|
  Fly   449 DGEHPPVYLPSLTAGDNRGVMSKALKGSGLEKPPSKSASNSPMMMKKAMAAEKAKKLPGSHTGSL 513

  Fly   619 KRRGLALELTA-----EQKQACLVNLTADPILSGTLFYLLPQGLVRIG------RG--------- 663
            ||:..|...::     ||.|   :.....||       .:|:.:|..|      :|
  Fly   514 KRQAGAGACSSPMIPHEQPQ---IQAMGSPI-------PIPRHMVSKGSMVPSPKGSPMRRAHPG 568

  Fly   664 ----RLPGGSSSSQPDIVLDGPLVA------LQHC--SIEHERGGKLYVIPGSEDFETYVNGELL 716
                :|..|......:..:|||.|:      .:|.  .:.|.:           ..||:|:|...
  Fly   569 AALEQLEAGMRKITEEQWIDGPRVSRAKVAEARHLMREVNHVK-----------QCETWVDGPKS 622

  Fly   717 KDRRQLFHGDRLVIGGSHYFRISNPFCSQRGKADHPVDFQLAHQEILQKQ------EQQLRSELE 775
            :..|.|...:....|||.               .....|..||::.:.:|      .|..:|.:.
  Fly   623 QSCRSLTACNLPAAGGSQ---------------TQGYGFMDAHKKTMIRQWVENQTTQVFQSTVS 672

  Fly   776 AEK--RAALTKIEQERAQHARDFEERLQCLELEQFKYKCNSEMLETERQALALAQQQEHTPLRHE 838
            |..  .|...|:.|.: |.:.|..:|      ..|..:.:.::.:...::|.|....  .|...|
  Fly   673 ASNSPTALHWKLSQLK-QKSLDLPDR------PAFNPEPSLDLNQPCFESLPLLDPA--PPDGDE 728

  Fly   839 DAVSTPAQKSTIL--------------EDIQRIM-LNPSEESLHKTQLMVKEATQ----RCRQLD 884
            |..|.|::....|              :::.|:: .:.|.|.||:.:|:...|:.    ..|.:|
  Fly   729 DEDSGPSEVPPALPLLDDPLGSRDISQDNLHRMLSRHVSREQLHEAELVASRASSSHHPSQRSID 793

  Fly   885 LPLEFRQTQTPDEFGLLRTVILILDKQRGLKAEWPTARLGVWLDLVRDNAEQQEKLNATTIFQSV 949
            ..|:..:.:      :.||                       :...||:......|:|.:...::
  Fly   794 CGLQVTEEE------IART-----------------------MSRDRDHDPSAHPLSALSHCDNI 829

  Fly   950 EVDWEPLDADLN---ETLSDTHNSSR-----------IALNLSAMKDV-------------LLNK 987
            .     ..:..|   |:.|:....:|           |..:..||.:|             :.::
  Fly   830 S-----FVSSFNMACESFSECGERARQQFDQLARLHEIFTSQLAMAEVTPSAALFRTDIGSVFSE 889

  Fly   988 PLKRLLNASSSKSNTPRQTSTPSPGSQLVHFTKRLLTYDPEEIPESQSSFTTL 1040
            |:.......||..:.|....||||..|            |...| ||.|..:|
  Fly   890 PVYHFNVGQSSVCSEPAYRLTPSPPKQ------------PSHSP-SQGSLPSL 929

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	79/430 (18%)
		KISc	120..525	CDD:214526	79/429 (18%)
		Kinesin_assoc	524..657	CDD:292801	34/186 (18%)
		FHA	634..740	CDD:238017	23/132 (17%)
CG14535	NP_001285726.1	Motor_domain	44..394	CDD:277568	87/471 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100