Protein Alignment neb and Klp3A

DIOPT Version :9

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: NP_001284830.1
• Gene: Klp3A / 31240
• FlyBaseID: FBgn0011606
• Length: 1212
• Species: Drosophila melanogaster
• Alignment Length: 1162
• Identity: 302/1162 - (25%)
• Similarity: 480/1162 - (41%)
• Gaps: 344/1162 - (29%)

  Fly   113 LSVSEESNMIVAVRVRPLNALECTRGQVTNVVQVHGNSNELTVQAGSSADASAGVTHFFSYDQVY 177
            :|..:.|.:.||:|||||...|..||....|.:....:.::||....|          ::|:.|
  Fly     1 MSSEDPSCVAVALRVRPLVQSELDRGCRIAVERSADGAPQVTVNRNES----------YTYNYV- 54

  Fly   178 YSCDPERKNFACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMGIEALDDAALDGGP 242
            :..|..:|:      :||...:..:.....|||..:.|||||||||:|:|        .....|.
  Fly    55 FDIDDSQKD------LFETCVQAKVKKLLNGYNVTILAYGQTGSGKTYTM--------GTAFNGV 105

  Fly   243 PHDEAGIIPRFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTPIQQ 307
            ..|..|:|||..|::|..|  .:.|.:.:..|..|:.|:|.|:.:||.|
  Fly   106 LDDHVGVIPRAVHDIFTAI--AEMQSEFRFAVTCSFVELYQEQFYDLFS---------------- 152

  Fly   308 QQQQQRPALKVRE--HPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHSI 370
            .:.:.:..:.:||  :.|..|.:.:|   .|.|...:.:.|..|::.||.|:||||:.|||||:|
  Fly   153 SKTRDKATVDIREVKNRIIMPGLTEL---VVTSAQQVTDHLIRGSAGRAVAATAMNETSSRSHAI 214

  Fly   371 FNIVLNLTDLSSDDGLSSDTDSSTASSLRQTRRSKISLVDLAGSERISVSGSNGERIREGVSINK 435
            |.:.|..|.|   ||..|.|            .|:.:|||||||||.|.:.::|:|.:|||:|||
  Fly   215 FTLTLVATKL---DGKQSVT------------TSRFNLVDLAGSERCSKTLASGDRFKEGVNINK 264

  Fly   436 SLLTLGKVIAALADSRKAIANGPLGSGTPSTFVPYRESVLTWLLRENLGGNSKTVMLATISPASI 500
            .||.||.||.|            ||||..:.::|||:|.||.||:::|||||.|:|:|.:|||..
  Fly   265 GLLALGNVINA------------LGSGQAAGYIPYRQSKLTRLLQDSLGGNSITLMIACVSPADY 317

  Fly   501 HADETLATLRYACKARSIVNRVKVNESPH-------DKIIRDLR--------------------- 537
            :..|||:|||||.:|..|.|:..||..||       ..:|:.||
  Fly   318 NVAETLSTLRYADRALQIKNKPVVNLDPHAAEVNMLKDVIQKLRVELLSGGKMSSSLISAVGAAG 382

  Fly   538 -----------------AEVDRLK-SLRNEYERQRRLSGNSNNPVPRKIIIETSVDETEVEALRQ 584
                             ||:.||| .:|...:|.|:|         ::.:.::.:|.||.| :|.
  Fly   383 LGAIPCEESLAGSMANAAEIQRLKEQVRTLQDRNRKL---------QQELHQSLLDLTEKE-MRA 437

  Fly   585 QLAERERELSRAQKSWMEKLKEAEDQRK------------SELR----VLKRRGLALELTAEQKQ 633
            .:||:..:..|   |.:.:||...|||:            :|:|    ::.|..:.|:.|.|:.:
  Fly   438 HIAEQAHDKLR---SHVSELKNKLDQREQAQFGNENTNGDNEMRDFSLLVNRVHVELQRTQEELE 499

  Fly   634 ACLVNLTADPILSGTLFYLLPQGLVRIGRGRLPGGSSSSQPDIVLDGPLVALQHCSIEHERGGKL 698
            :                    ||  ...|.||   ||.|                   |..||:
  Fly   500 S--------------------QG--HESRQRL---SSRS-------------------HTEGGE- 519

  Fly   699 YVIPGSEDF--------ETYVN------GELLKDRRQLFHGDRLVIGGSHYFRISNPFCSQRGKA 749
               .|.::.        |.|.|      |||....|||.....|      :.||...| |:....
  Fly   520 ---SGGDEVHEMLHSHSEEYTNKQMNFAGELRNINRQLDLKQEL------HERIMRNF-SRLDSD 574

  Fly   750 DHPVDFQLAHQEI---------LQKQEQQLRS-----ELEAEKRAALTKIEQERAQ--------- 791
            |..|..:|.:|:|         |..|.:.::|     :|..|:|..|..:|||.:.
  Fly   575 DEDVKLRLCNQKIDDLEAERRDLMDQLRNIKSKDISAKLAEERRKRLQLLEQEISDLRRKLITQA 639

  Fly   792 ---HARDFE-ERLQCLELE-----QFKYKCNSEML-ETER-QALALAQQQEHTPLRHED--AVST 843
               ..||.| |::|.|..|     :.|.|....|. |:|: :...:.:::|.|.|:.:|  ..|.
  Fly   640 NLLKIRDKEREKIQNLSTEIRTMKESKVKLIRAMRGESEKFRQWKMVREKELTQLKSKDRKMQSE 704

  Fly   844 PAQKSTILEDIQRIMLNPSEESLHKTQLMVKEATQRCRQLDLPLEFRQTQTPDEFGL-------- 900
            ..::.|:....::::....||:|...: .:|:|.:|    ....:.::.:..|..|.
  Fly   705 IVRQQTLHSKQRQVLKRKCEEALAANK-RLKDALER----QASAQAQRHKYKDNGGSAAGSSNAN 764

  Fly   901 ----------LRTVILILDKQRGLKAEWPTARLGVWLDLVRDNAE--------QQEKLN------ 941
                      |..::.::|.:..|:            .|:.|.|.        ||||.:
  Fly   765 AKTDSWVDRELEIILSLIDAEHSLE------------QLMEDRAVINNHYHLLQQEKTSDPAEAA 817

  Fly   942 -ATTIFQSVEVDWEPLDA---DLNETLSDTHNSSRI----------ALNLSAMKDVLLNKPLKRL 992
             ...|..|:|.:.|..:|   ||.:.:..|...|||          ..:.:..|.:|.....:|.
  Fly   818 EQARILASLEEELEMRNAQISDLQQKVCPTDLDSRIRSLAEGVQSLGESRTVSKQLLKTLVQQRR 882

  Fly   993 LNASSSKSNTPRQTSTPSPGSQLVH-------FTKRLLTYDPEEIPESQSSFTTLVQQ-----EL 1045
            |.|||...   ::|:.....:||:.       .:|||      .:.:||.....|.||     ::
  Fly   883 LQASSLNE---QRTTLDELRAQLLDAQQQEDAASKRL------RLLQSQHEEQMLAQQRAYEEKV 938

  Fly  1046 QIMQRSAQRLRRHCEAALLERENHQDNGVL--AVSLQEALARMDTVLNGMHTSLARA 1100
            .::.|:|.  :|..||. ...|:.|.|.:|  .:|.:|||.:....|...:.|.::|
  Fly   939 SVLIRTAN--QRWAEAR-SPAEDQQRNQILEELLSSREALQQELDKLRAKNKSKSKA 992

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	143/407 (35%)
		KISc	120..525	CDD:214526	142/406 (35%)
		Kinesin_assoc	524..657	CDD:292801	37/194 (19%)
		FHA	634..740	CDD:238017	24/119 (20%)
Klp3A	NP_001284830.1	KISc_KIF4	7..336	CDD:276823	141/401 (35%)
		Kinesin	14..335	CDD:278646	138/393 (35%)
		Smc	<396..>994	CDD:224117	151/694 (22%)
		FlaC	522..633	CDD:225888	29/117 (25%)
		TCR	1075..1110	CDD:281618

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437982
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930