DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment neb and KIF4A

DIOPT Version :9

Sequence 1:NP_476817.1 Gene:neb / 35293 FlyBaseID:FBgn0004374 Length:1121 Species:Drosophila melanogaster
Sequence 2:NP_036442.3 Gene:KIF4A / 24137 HGNCID:13339 Length:1232 Species:Homo sapiens


Alignment Length: Identity:/ - (0%)
Similarity:/ - (0%) Gaps:/ - (0%)


- Green bases have known domain annotations that are detailed below.


Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nebNP_476817.1 KISc_KIF1A_KIF1B 119..525 CDD:276816
KISc 120..525 CDD:214526
Kinesin_assoc 524..657 CDD:292801
FHA 634..740 CDD:238017
KIF4ANP_036442.3 KISc_KIF4 8..337 CDD:276823
SMC_prok_B <375..714 CDD:274008
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 496..515
Smc 558..>918 CDD:224117
Required for the interaction with PRC1. /evidence=ECO:0000269|PubMed:15297875 663..1232
Nuclear localization signal. /evidence=ECO:0000269|PubMed:11736643 793..798
Globular 1000..1232
Pre-SET <1078..1120 CDD:368254
CRD, required for [4Fe-4S] cluster binding and localization to the spindle midzone and midbody during anaphase and telophase. /evidence=ECO:0000269|PubMed:29848660 1086..1144
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1122..1142
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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