Protein Alignment neb and Klp64D

DIOPT Version :10

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: XP_312517.6
• Gene: Klp64D / 1273532
• VectorBaseID: AGAMI1_004514
• Length: 685
• Species: Anopheles gambiae
• Alignment Length: 763
• Identity: 226/763 - (29%)
• Similarity: 344/763 - (45%)
• Gaps: 201/763 - (26%)

  Fly   110 ESCLSVSEESNMIVAVRVRPLNALECTRGQVTNVVQVHGNSNELTVQAGSSADASAGVTHFFSYD 174
            |:..:..|..|:.|.|||||::..|...|. .||::|..::..:||...::..:.....::|  |
Mosquito     4 EAIKNEGEIENVRVVVRVRPMDKSELDVGS-QNVIKVDKSNRSITVVKPNANSSEPPKVYYF--D 65

  Fly   175 QVYYSCDPERKNFACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMGIEALDDAALD 239
            .|:       ...:.|..::..||||::|...||||..:.||||||:||:|:|.|         .
Mosquito    66 NVF-------GEDSTQIDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSG---------S 114

  Fly   240 GGPPHDEAGIIPRFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTP 304
            ...|..: ||||.....:|..|...|..|:..  |.|||.|||||::.|||.
Mosquito   115 ADSPQTK-GIIPNTFAHIFGHIARGKENQKFL--VRVSYMEIYNEEVRDLLG------------- 163

  Fly   305 IQQQQQQQRPALKVREHPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHS 369
                 ::...:|:|:|....|.:|.|||.:.|.:...|.|.:.:||..|...:|.||.:|||||:
Mosquito   164 -----KELNKSLEVKERADIGVFVKDLSGYVVHNADDLDNIMKLGNKNRVVGATKMNSESSRSHA 223

  Fly   370 IFNIVLNLTDLSSDDGLSSDTDSSTASSLRQTRRSKISLVDLAGSERISVSGSNGERIREGVSIN 434
            ||:|.:.          ||:||.   :..:..|..|:.|||||||||.|.:.|:|.|::|...||
Mosquito   224 IFSITVE----------SSETDE---AGRQYVRMGKLQLVDLAGSERQSKTQSSGLRLKEATKIN 275

  Fly   435 KSLLTLGKVIAALADSRKAIANGPLGSGTPSTFVPYRESVLTWLLRENLGGNSKTVMLATISPAS 499
            .||..||.||:||.|.:             ||.:|||.|.||.||:::|||||||||.|:||||.
Mosquito   276 LSLSVLGNVISALVDGK-------------STHIPYRNSKLTRLLQDSLGGNSKTVMCASISPAD 327

  Fly   500 IHADETLATLRYACKARSIVNRVKVNESPHDKIIRDLRAEVDRLKSLRNEYERQRRL-SGNSNNP 563
            .:..||::||||||:|:||.|...:||.|.|.::|..:.|::.||....|...|:.: ||:...
Mosquito   328 SNYVETISTLRYACRAKSIQNLAHINEEPKDALLRHFQEEIEELKRQLEEGIFQQGIESGDEEE- 391

  Fly   564 VPRKIIIETSVD---ETEVEALRQQL---AERERE-LSRAQKSWMEKLKEAEDQRKSELRVLKRR 621
                   |...|   |.|.:|:.::.   |:|||| |.|.:|...||.:|.:::..:|..:|:::
Mosquito   392 -------EEDGDGEGEDEEDAVEEECDPDADRERERLERKEKQRKEKARERKEKSDAEKELLEKK 449

  Fly   622 GLALELTAEQKQACLVNLTADPILSGTLFYLLPQGLVRIGRGRLPGGSSSSQPDIVLDGPLVALQ 686
              |:|...|.|:|                                    .|:.| .|...|.:|:
Mosquito   450 --AMENQQELKKA------------------------------------KSEQD-QLRAKLSSLE 475

  Fly   687 HCSIEHERGGKLYVIPGSEDFETYVNGELLKDRRQLFHGDRLVIGGSHYFRISNPFCSQRGKADH 751
                                                   :::::||.:..        ::.|
Mosquito   476 ---------------------------------------NKILVGGENLL--------EKAK--- 490

  Fly   752 PVDFQLAHQEILQKQ---EQQLRSELEAEKRAALTKIEQERAQHARDFEERLQCLELE----QFK 809
                   .||:|.:.   |.:.|::.|.|.:..|.|||.||.    |.|||...|:.|    ..|
Mosquito   491 -------EQELLLENSITELEQRTKTERELKENLQKIEAERI----DIEERYSSLQEECVGKTKK 544

  Fly   810 YKCNSEMLETERQALALAQQQEHTPLRHEDAVSTPAQKSTILEDIQRI 857
            .:....||.:.:..||..||::.            .:|..|.|:|:.:
Mosquito   545 LQRVMSMLMSIKSELADQQQEQQ------------REKEGIYENIRSL 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	151/405 (37%)
		SMC_N	514..>615	CDD:481474	32/108 (30%)
		FHA_KIF14	627..741	CDD:438759	10/113 (9%)
Klp64D	XP_312517.6	None