Protein Alignment neb and LOC108648793

DIOPT Version :10

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: XP_017952709.2
• Gene: LOC108648793 / 108648793
• XenbaseID: XB-GENE-29091223
• Length: 1140
• Species: Xenopus tropicalis
• Alignment Length: 954
• Identity: 288/954 - (30%)
• Similarity: 430/954 - (45%)
• Gaps: 234/954 - (24%)

  Fly   123 VAVRVRPLN------ALECTRGQVTNVVQVHGNSNELTVQAGSSADASAGVTHFFSYDQVYYSCD 181
            ||||.||:|      ..||       ||||.||...| :...|..:....|...|::|..:.:.|
 Frog     8 VAVRARPMNHRENELKSEC-------VVQVKGNQIFL-LPPPSHKEDHMKVKKEFTFDHCFLTVD 64

  Fly   182 PERKNFACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMGIEALDDAALDGGPPHDE 246
               :|.|.|.:||......|:|..|:|:|||:|||||||||||:||||.:             ::
 Frog    65 ---ENHAGQEEVFSVLGSELVDNVFKGFNACIFAYGQTGSGKSFSMMGTD-------------EQ 113

  Fly   247 AGIIPRFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTPIQQQQQQ 311
            .|:||....|||:|     .....|:.||||:.||||||:.|||                 |.::
 Frog   114 PGLIPMISSELFKR-----EHNSRQLRVEVSFMEIYNEKVRDLL-----------------QSKE 156

  Fly   312 QRPALKVREHPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHSIFNIVLN 376
            .:..|||||...|||||..||.|:|.:|..:...:...|..|.||:|.|||.|||||:||:|.::
 Frog   157 NQKTLKVRESKQFGPYVEGLSHHTVSNYENINCLVLKANKHRTTAATNMNDVSSRSHAIFSITVS 221

  Fly   377 LTDLSSDDGLSSDTDSSTASSLRQTRRSKISLVDLAGSERISVSGSNGERIREGVSINKSLLTLG 441
            ...:          :.||.|:...|  .||||||||||||:|.:|:.||.::|..:|||||..||
 Frog   222 QIHI----------NHSTGSTRELT--GKISLVDLAGSERVSKTGAEGEHLKESKNINKSLTALG 274

  Fly   442 KVIAALADSRKAIANGPLGSGTPSTFVPYRESVLTWLLRENLGGNSKTVMLATISPASIHADETL 506
            :||.||::.:             :::|.||:|||||||:.|||||||||||||||||:.:..|||
 Frog   275 RVIFALSEGK-------------ASYVNYRDSVLTWLLKNNLGGNSKTVMLATISPAADNYHETL 326

  Fly   507 ATLRYACKARSIVNRVKVNESPHDKIIRDLRAEVDRLKSLRNEYERQRRLSGNSNNPVPRKIIIE 571
            :||.||..|:.|||:..|||....|.|.:|:.||..||...::.|...|
 Frog   327 STLTYADSAKRIVNQAVVNEDTTCKAIGELQEEVRILKEKLSQAEGMHR---------------- 375

  Fly   572 TSVDETEVEALRQQLAERERELSRAQKSWMEKLK--EAEDQRKSELRVLKRRGLALELTAEQKQA 634
                  :::.|:.:|.|:|..|.....:|.|||:  |...:|:..|.       ::.:|.||
 Frog   376 ------DLQELQSKLREKEDLLEELNMTWEEKLQNFEVMQERQKHLD-------SMGITVEQ--- 424

  Fly   635 CLVNLTADPILS-----------GTLFYLLPQGLVRIGRGRLPGGSSSSQPDIVLDGPLVALQHC 688
              :.:..||..|           ..||||.....|         |:.:|| ||.|:||.:.|.||
 Frog   425 --LGIRIDPQKSYLFPIHHHPEHTYLFYLKENTSV---------GAGTSQ-DIQLNGPGIELDHC 477

  Fly   689 SIEHERGGKLYVIPGSEDFETYVNGELLKDRRQLFHGDRLVIGGSHYFRISNPFCSQRGKADHPV 753
            .|....|    .:...|:..|||||.|:.....|:.||::.: ||:.|.|..|.
 Frog   478 VINILEG----FVTSKENAPTYVNGCLVCKSTDLWDGDKITL-GSYTFMIHLPH----------- 526

  Fly   754 DFQLAHQEILQKQEQQLRSELEAEKRAALTKIEQER---------AQHARDFEERLQCLELEQFK 809
                      :|:.:.:.:..|.:.||......|.:         ..|..:..|.....:
 Frog   527 ----------RKRTESVNNYTEEQIRADSLSFTQGKDILAGYDNITYHNNNSTEGSSSPD----- 576

  Fly   810 YKCNSEMLETERQALALAQQQEHTPLRHEDAVST-PAQKSTILEDIQRIMLNPSEES-------- 865
            ::.||:....::::..|    |.:....||:.|| ...|::..::|.|   :||:|.
 Frog   577 FRPNSDCPMADKRSSVL----ERSAKLEEDSYSTNKLSKASQHDNISR---SPSQEGSPTMSSAT 634

  Fly   866 --------LHKTQLMV-KEAT----QRCRQLDLPL-------EFRQTQTP-DEFGLLRTVILILD 909
                    ::|.|:.: .|||    .|.:.::...       ::.:|:.| .||. .||.:|...
 Frog   635 KGRDTLVHMNKVQITLDTEATDSLLNRFKNINTVEIDGQSHGKYNKTKRPFSEFP-ARTNVLPPI 698

  Fly   910 KQRGLKAEWPTARLGVWLDLVRDNAEQQEKLNATTIFQSVEVDWEPLDADLNETLSDTHNSSRIA 974
            ....:.::..||..|...::...|      :|...|.|            .::|..:..||   .
 Frog   699 HSLSITSQVGTAVDGTVCEIPCHN------INNCVISQ------------YDKTAQEHCNS---P 742

  Fly   975 LNLSAMKDVLLNKPL-KRLLNASSSKSNTPRQTSTPSPGSQLVH 1017
            :..|:..|...|..: ||.:::..:.|...|...|.|...:.:|
 Frog   743 VRQSSATDTKANSDVQKRAIDSGRNSSCQERNNDTISDQQEFLH 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	171/407 (42%)
		SMC_N	514..>615	CDD:481474	27/102 (26%)
		FHA_KIF14	627..741	CDD:438759	38/124 (31%)
LOC108648793	XP_017952709.2	Motor_domain	5..345	CDD:473979	171/407 (42%)
		Kinesin_assoc	342..453	CDD:465047	34/144 (24%)
		FHA	433..529	CDD:469597	34/131 (26%)