Protein Alignment neb and kif1a

DIOPT Version :9

• Sequence 1: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Sequence 2: XP_031758411.1
• Gene: kif1a / 100127546
• XenbaseID: XB-GENE-960470
• Length: 1830
• Species: Xenopus tropicalis
• Alignment Length: 1193
• Identity: 335/1193 - (28%)
• Similarity: 508/1193 - (42%)
• Gaps: 328/1193 - (27%)

  Fly   123 VAVRVRPLNALECTRGQVTNVVQVHGNSNELTVQAGSSADASAGVTHFFSYDQVYYS-CDPERKN 186
            |||||||.|:.|..:.... ::|:.||:..:.     :..........||:|..|:| ...|...
 Frog     8 VAVRVRPFNSREIGKDSKC-IIQMSGNTTTIV-----NPKQPKETPKSFSFDYSYWSHTSEEDSQ 66

  Fly   187 FACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMGIEALDDAALDGGPPHDEAGIIP 251
            :|.|.:|:......::..||||||.|:|||||||:||||:|||.:           ...:.||||
 Frog    67 YAGQRQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQ-----------EPTQQGIIP 120

  Fly   252 RFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTPIQQQQQQQRPAL 316
            :.|.:||.||... :...:...|||||.|||.|::.|||:                  .:.:..|
 Frog   121 QLCEDLFSRISDT-TNDNMSYSVEVSYMEIYCERVRDLLN------------------PKNKGNL 166

  Fly   317 KVREHPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHSIFNIVLNLTDLS 381
            :|||||:.||||.|||..:|.||..:::.:..||..|..|:|.||:.|||||::|||:....
 Frog   167 RVREHPLLGPYVEDLSKLAVTSYQDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQR--- 228

  Fly   382 SDDGLSSDTDSSTASSLRQTRRSKISLVDLAGSERISVSGSNGERIREGVSINKSLLTLGKVIAA 446
                 ..|.|:.|.:.    :.|||||||||||||...:|:.|.|::||.:|||||.||||||:|
 Frog   229 -----RHDADAQTTTE----KVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISA 284

  Fly   447 LADSRKAIANGPLGSGT-------PSTFVPYRESVLTWLLRENLGGNSKTVMLATISPASIHADE 504
            ||:         :.|||       .:.|:|||:|||||||||||||||:|.|:|.:|||.|:.||
 Frog   285 LAE---------MDSGTNKNKKKKKNDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDE 340

  Fly   505 TLATLRYACKARSIVNRVKVNESPHDKIIRDLRAEVDRLKSL----------------------- 546
            ||:|||||.:|:.|.....:||.|::::||:|:.||.||:.|
 Frog   341 TLSTLRYADRAKQIRCNAVINEDPNNRLIRELKDEVARLRDLLGAQGLSDIIDNVCPVDNGNVLH 405

  Fly   547 -----RNEYERQRRLSGNSNNPVPRKIIIETSVDETEVEALRQQLA-------------EREREL 593
                 .|.:.....|:|.|    |...:...|.....|.:|.::||             |.|:.:
 Frog   406 KRHAADNLFTAVNALTGMS----PSSSMSGLSSRAASVTSLHERLAFTPGSEEAIERLKETEKII 466

  Fly   594 SRAQKSWMEKLKEAEDQRKSELRVLKRRGLA-------LELTAEQKQACLVNLTADPILSGTLFY 651
            :...::|.|||:..|..|.....:|...|:|       |.:.:.:|...||||..||::|..|.|
 Frog   467 AELNETWEEKLRRTEAIRMDREALLAEMGVAMREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLY 531

  Fly   652 LLPQGLVRIGRGRLPGGSSSSQPDIVLDGPLVALQHCSIEHE---RGGKLYVIPGSEDFETYVNG 713
            .:..|:.|:||     ..::.:.||||.|..:..:||....:   .|..:..:...:..:|||||
 Frog   532 YIKDGITRVGR-----EDATMRQDIVLSGHFIRDEHCIFRSDVLACGSVVVTLEPCDGADTYVNG 591

  Fly   714 ELLKDRRQLFHGDRLVIGGSHYFRISNPFCSQRGK--------ADHPVDFQLAHQEILQKQE--- 767
            :.|.|...|..|:|:::|.||.||.::|..:::.:        ...|||:..|.:|:|:||.
 Frog   592 KKLTDPCILRSGNRIIMGKSHVFRFNHPEQARQERERTPCAETPSEPVDWAFAQRELLEKQGIDM 656

  Fly   768 --------QQLRSELEAEKRAALTKIEQERAQHARDFEERLQCLELE---QFKYKCNSEMLETER 821
                    |:|..:...|:..|...:||:|.    |:|.||:.|:.:   ::..:.|.|..|.|.
 Frog   657 KQEMDQRLQELEDQYRKEREEANYLLEQQRL----DYESRLEALQRQMDSRYFTEVNEEEEEPED 717

  Fly   822 QALALAQQ-------------QEHTPLRHE-----------DAVSTPAQKSTILEDIQRIMLNPS 862
            :.....|:             .:.|.||.:           :|:|...:|..   ..|.::|..:
 Frog   718 EVQWTEQEYDLALWAFRKWKWYQFTSLRDQLWGNAIFLKEANAISVELKKKV---QFQFVLLTDT 779

  Fly   863 EESLHKTQLMVKEATQRCRQLDLPLEFRQTQTPDEFGLLRTVIL--ILDKQRGLKAEWPTARLGV 925
            ..|.....|:..:|.....:...|               ||::.  :.|::.|....|...:|..
 Frog   780 LYSPLPPDLLPPDAHTEREKRPFP---------------RTIVAVEVQDQKNGATHYWTLEKLRQ 829

  Fly   926 WLDLVR-----------------DNA--------------------------------------- 934
            .||::|                 ||.
 Frog   830 RLDMMREMYDRAAELPSGLTEDCDNVVTGGDPFYDRFPWFRLVGSSPLFTTCMSESMAEITPSPT 894

  Fly   935 ---------EQQEKLNATTIFQ-SVEVDWEPLDADLNETLSDT-HNSS-------RIALNLSAMK 981
                     |...:|....||| ..|.|..|.:.......||. |:.|       |..:.||
 Frog   895 LSSPGSEGPEPASQLEEEDIFQDDEEEDDGPQEHPCCAVRSDPFHDRSPLFSVVGRAFVYLS--- 956

  Fly   982 DVLLNKP-----------------LKRLLNASSSKSNTP------RQTSTPSPGSQLVHFTKRLL 1023
            ::|.:.|                 |:..:.|.|:....|      ||:.|........||.|
 Frog   957 NLLYSVPLVHRVAIVSEKGEVKGFLRVAVQAISADEEAPDYGSGVRQSGTAKISFDDQHFQK--- 1018

  Fly  1024 TYDPEEIPESQSSFTTLVQQELQIMQRSAQRLRRHCEAALLERENHQDNGVLAVSLQEALARMDT 1088
             :..|..|....|.|:  |:||:|::....:....|.:|     :..:|...|.|||.:|
 Frog  1019 -FQAETCPGMTRSGTS--QEELRIVEGGQGQNPDSCPSA-----DEVNNNTCAASLQSSL----- 1070

  Fly  1089 VLNGMHTSLARAEATACVTSPTK 1111
                             :.||||
 Frog  1071 -----------------LDSPTK 1076

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	169/409 (41%)
		KISc	120..525	CDD:214526	169/409 (41%)
		Kinesin_assoc	524..657	CDD:292801	43/180 (24%)
		FHA	634..740	CDD:238017	36/108 (33%)
kif1a	XP_031758411.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D76316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010