DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10730 and CG15695

DIOPT Version :9

Sequence 1:	NP_610021.3	Gene:	CG10730 / 35291	FlyBaseID:	FBgn0032843	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_650920.3	Gene:	CG15695 / 42468	FlyBaseID:	FBgn0038832	Length:	725	Species:	Drosophila melanogaster

Alignment Length:	614	Identity:	224/614 - (36%)
Similarity:	337/614 - (54%)	Gaps:	52/614 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 YYVYSPVCQMPAVNPFTWDTMSNFHRKTLRHCHNDSDMVTSEFDFETHQYRLHVHEHLAKPIMNR 95
            |:|:||.|||...|||..:....:.:.:...|....||:|..::.....||||.:|
  Fly   156 YFVHSPQCQMSHPNPFANNIQHIYKKHSYIVCDKSRDMITVNYNVTDSTYRLHKNE--------- 211

  Fly    96 KGNATLECEYQEISRDNSDQKPDNAYNQLRRRP-IEQHQ--FVPNNTDYMITSCYVRDVTKHREL 157
              |:|  |.:::|.|..:....|:.|   :..| :|.||  .||.....|||.|......|   :
  Fly   212 --NST--CCFKQILRAGTSANADHKY---KLGPCVEFHQDFLVPTEVSAMITYCRRPPFDK---V 266

  Fly   158 LQQDAISFIEDRLPKEKVKDFVKDESEVH--KPSVLIMGLDSTSRINLRRAMPSVYKFVRQPGWF 220
            .|:||.||:..|      ||.:::.:..|  :||||:.|:||.||:||...||.:|:::....||
  Fly   267 SQKDAFSFVHPR------KDQIENPTTPHRRRPSVLLWGIDSISRMNLELTMPRMYEYLNNQHWF 325

  Fly   221 EMQGYNKVGDNTFPNLLAALTGDSEKGVGDYCDVTKPGCLDSLNFIWKRFKKANYTTAFAEDCSS 285
            |:|||||:||||||||:|.|||.::......|...|...||:..||||.||...||||||||.|.
  Fly   326 ELQGYNKMGDNTFPNLMAVLTGFNKTYANARCHPEKVRGLDACPFIWKDFKDKGYTTAFAEDWSK 390

  Fly   286 ISTFNYLKPGFVKQPTDYYLRPLLFAIEKQFKVTNDFGFAYCVGRHLSFSYVWDFGQQF--IDRF 348
            .|||:|...||...|||.|.|||:.|:||:..:.......||:||..:..|::|.|.||  ::|
  Fly   391 FSTFDYSSRGFFNPPTDVYGRPLVLAVEKELTILQRGQMPYCLGRKPASEYIYDMGVQFTMVNR- 454

  Fly   349 LGRSPMFGFLWSNSFTHDYYEGATALDNLLWKYLKSFEESNLFQKSIVILMSDHGHRYNTLRRAS 413
              .|..||..|:|:|:|:.:...:|:|..:.||:::.:::.:...:|:|..||||.|:..||...
  Fly   455 --NSTFFGMFWTNTFSHNDFSMPSAMDERMVKYMRTLDKNGIMDNTIIIFFSDHGSRFGPLRNLD 517

  Fly   414 TGYFEERMPMMFIYLPPWFRRKYPHLASNLGKNQNRLSSNYDVYMTLQHLLQLDSKSVDEFPDNL 478
            :|:.|||:|.::|.:|.|.|.|||.|..||..|:|||:|.||::.||:|:|:||:.. |:.|
  Fly   518 SGFVEERLPFIYIRVPRWIREKYPKLLRNLQMNKNRLTSPYDIHATLRHILELDTPK-DKLP--- 578

  Fly   479 RARQCKSCQSLFFELPFNRTCQMAGIEEKWCCCQP-TETITNSPHVSTIAEAIVQRMNEHLISHN 542
            |...|.||.|:|.|:.::|.|..||||:.||.|.. ::..|..|...:::..:|:.:||::.|..
  Fly   579 RPDGCSSCHSVFEEVDWSRNCSQAGIEDHWCACNSFSDVPTTDPSARSMSTQLVEAINEYVASKK 643

  Fly   543 LSDLCHNFTLDYVEKADRKTILSNGLRPADKNEQVYIIVFETVPKNPIFEATVRWNSRTQRLLHF 607
            .:..|....|:.:....|:           .|...|:|.....|.:.:|||||.|::..|| :..
  Fly   644 GTKRCSRLKLNRISSVQRR-----------GNSNRYLIQLMAQPGDALFEATVDWDASAQR-IPA 696

  Fly   608 DVEELSRLTSYKNDANCINRKNAKKYCIC 636
            .:..:|||.:|...:.|.:.|..||||||
  Fly   697 QMPSISRLDTYAAKSRCSSVKETKKYCIC 725

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10730	NP_610021.3	DUF229	55..556	CDD:281053	189/508 (37%)
CG10730	NP_610021.3	ALP_like	188..467	CDD:293745	125/280 (45%)
CG15695	NP_650920.3	DUF229	180..656	CDD:281053	189/507 (37%)
CG15695	NP_650920.3	ALP_like	293..571	CDD:293745	125/280 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469414
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D31599at6960
OrthoFinder	1	1.000	-	-		FOG0005924
OrthoInspector	1	1.000	-	-		mtm4742
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10974
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.950