DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10730 and CG9168

DIOPT Version :9

Sequence 1:	NP_610021.3	Gene:	CG10730 / 35291	FlyBaseID:	FBgn0032843	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_612106.2	Gene:	CG9168 / 38163	FlyBaseID:	FBgn0035216	Length:	648	Species:	Drosophila melanogaster

Alignment Length:	615	Identity:	299/615 - (48%)
Similarity:	405/615 - (65%)	Gaps:	15/615 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 YYVYSPVCQMPAVNPFTWDTMSNFHRKTLRHCHNDSDMVTSEFDFETHQYRLHVHEHLAKPIMNR 95
            :||.||.|:||.::||:.|.|..|.|:..|.|.:|.|::.||||....|||:.:.|:.|:..:.:
  Fly    40 FYVDSPSCKMPEMDPFSADIMRFFKRRQFRECSSDKDLLISEFDSHLRQYRIKIDENSAQQHLKK 104

  Fly    96 KGNATLECEYQEISRDNSDQKPDNAYNQLRRRPIEQHQFVPNNTDYMITSCYVRDVTKHRELLQQ 160
            .|||||:||||.|.|:..|..|||.::..:.:|:.|...||...|::.|.|:........:|||:
  Fly   105 FGNATLKCEYQVIGRNKKDSFPDNHFSFSKLQPLSQSFLVPKTIDFISTQCHAVHGNIDLKLLQK 169

  Fly   161 DAISFIEDRLPKEKVKDFVKDESEVH------KPSVLIMGLDSTSRINLRRAMPSVYKFVRQPGW 219
            ||..|::|||..|      ...:|.|      ||:|:|:|:|||||:||||:||.|:||:::|||
  Fly   170 DAFLFVQDRLNHE------HKNTEHHRPDLQSKPNVIILGIDSTSRMNLRRSMPKVHKFLQRPGW 228

  Fly   220 FEMQGYNKVGDNTFPNLLAALTGDSEKGVGDYCDVTKPGCLDSLNFIWKRFKKANYTTAFAEDCS 284
            ||||||||||:||.|||||.|||::|:...........|.:|.|.|||:.|||..|.|||.|||:
  Fly   229 FEMQGYNKVGENTLPNLLAILTGNAEENALFNGRFGHSGFIDKLKFIWQLFKKNGYMTAFGEDCA 293

  Fly   285 SISTFNYLKPGFVKQPTDYYLRPLLFAIEKQFKVTNDFGFAYCVGRHLSFSYVWDFGQQFIDRFL 349
            .|:||||.||||.:||.|:|||..:.|:|...|...:||..:|:||.|.|.||:||.:||:.||.
  Fly   294 KINTFNYQKPGFKQQPVDFYLRNFIVALETILKTRREFGNVFCLGRKLGFQYVFDFARQFMQRFE 358

  Fly   350 GRSPMFGFLWSNSFTHDYYEGATALDNLLWKYLKSFEESNLFQKSIVILMSDHGHRYNTLRRAS- 413
            ..:|:||..|||||||:.:.||||||::..:||..::|...|.:|||:::||||:||...|:||
  Fly   359 NSAPVFGIFWSNSFTHEDFLGATALDHVFLEYLTLYDELGFFNRSIVMVLSDHGYRYGVTRQASK 423

  Fly   414 TGYFEERMPMMFIYLPPWFRRKYPHLASNLGKNQNRLSSNYDVYMTLQHLLQLDSKSVDEFPDNL 478
            :||.|||:|:|||::|||||:.||....||..|||||||.:|::|||.|||.|::.|:.:|...|
  Fly   424 SGYLEERLPLMFIHVPPWFRKIYPQYVENLKINQNRLSSGFDLHMTLHHLLHLNATSMADFSPKL 488

  Fly   479 RARQCKSCQSLFFELPFNRTCQMAGIEEKWCCCQPTETITNSPHVSTIAEAIVQRMNEHLISHNL 543
            :|.|||.||||||:||.||.|..|||.||||.|:||||:||...:..:|:.:|..||.||...||
  Fly   489 QASQCKMCQSLFFQLPANRNCSHAGIREKWCSCEPTETVTNQRLLRKVAQEVVHHMNRHLRDRNL 553

  Fly   544 SDLCHNFTLDYVEKADRKTILSNGLRPADKNEQVYIIVFETVPKNPIFEATVRWNSRTQRLLHFD 608
            :.||.|:.|..|...|.|..||.. ...|:....|||.|||.|.:..|||||:|||. :..|:.:
  Fly   554 TTLCQNYALKKVLYLDSKISLSED-SVEDEQLHTYIITFETNPSSAHFEATVQWNSE-KETLNMN 616

  Fly   609 VEELSRLTSYKNDANCINRKNAKKYCICKD 638
            |:|||||.||:..:.|......|||||||:
  Fly   617 VDELSRLESYEKHSKCTRDPIIKKYCICKE 646

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10730	NP_610021.3	DUF229	55..556	CDD:281053	249/507 (49%)
CG10730	NP_610021.3	ALP_like	188..467	CDD:293745	155/279 (56%)
CG9168	NP_612106.2	DUF229	64..566	CDD:308570	249/507 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469410
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D31599at6960
OrthoFinder	1	1.000	-	-		FOG0005924
OrthoInspector	1	1.000	-	-		mtm4742
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10974
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.950