Protein Alignment CG10730 and R03G8.3

DIOPT Version :10

• Sequence 1: NP_610021.3
• Gene: CG10730 / 35291
• FlyBaseID: FBgn0032843
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_510174.3
• Gene: R03G8.3 / 181437
• WormBaseID: WBGene00010998
• Length: 654
• Species: Caenorhabditis elegans
• Alignment Length: 706
• Identity: 152/706 - (21%)
• Similarity: 265/706 - (37%)
• Gaps: 136/706 - (19%)

  Fly     3 LSRKDF---QALLIVICF-------GFWIENLVQGADDYY-VYSPV------------------- 37
            ||:.::   :|||:..||       ||.:.:.:.....|. :|.|:
 Worm     5 LSKMEYVPWKALLVTGCFAMYLVLLGFTMFSPLLSPQQYLGLYQPISGNIPSKVVMNKSEVEPWD 69

  Fly    38 -CQMPAVNPFTWD----TMSNFHRKTLRHCHNDSDMVTSEFDFETHQYRLHVHEHLAKPIMNRKG 97
             |::|..:  .||    ...|.....:.:|:...:.:|                     .:|...
 Worm    70 QCELPQYD--IWDDEILPYLNMEVNPISNCNKSREPLT---------------------FLNNGS 111

  Fly    98 NATLECEYQEISRDNSDQKPDNAYNQLRRRPIEQHQFVPNNTDYMITSCYVRDVTKHRELLQQDA 162
            ...:..:.:.|.|.....:....||     .|....:.|...:..:......|..|       |.
 Worm   112 WGVVNKKTKLICRARCHTRKSERYN-----VIGNWTYTPGPINCEVVEAVCADGKK-------DV 164

  Fly   163 ISFIEDRLPKEKVKDFVKDESEVHKPSVLIMGLDSTSRINLRRAMPSVYKFVRQPGWFEMQGY-N 226
            ..|:..::.....|......||:....|.::.|||.|....:|::.....::.......:..| |
 Worm   165 YGFLHTQVIATPPKQPTVKVSELKNYDVTVIMLDSLSFTQAKRSLLRTISYMTNHMDAVLFPYIN 229

  Fly   227 KVGDNTFPNLLAALTGDS----------EKGVG-DY-----CDVTKPGCLDSLNFIWKRFKKANY 275
            |||||:.||..|...|.|          |:.|. |:     |.|.|    |:...::|.::...|
 Worm   230 KVGDNSRPNGAALWFGKSLEKLDRSLFEEENVPVDWSHAYMCHVYK----DNETSLFKEYQNYGY 290

  Fly   276 TTAFAEDCSSISTFNYLK-PGFVKQPTDYYLRPLLFAIEK--------QFKVTNDFGFAYCVGRH 331
            .|..|||.:. .|.|:.. .||.|.|.|:.:||...|:|:        :..:.|.   .||...|
 Worm   291 KTLMAEDWAE-GTLNWPNCKGFDKPPIDHLMRPFQNALERANHGEPLTKSHLKNQ---KYCREDH 351

  Fly   332 LSFSYVWDFGQQFIDRFLGRSPMFGFLWSNSFTHDYYEGATALDNLLWKYLKSFEESNLFQKSIV 396
            .:   :.|:..|||:.:..:: .|.::|::...||...|....|....|:|....|.  ...|.|
 Worm   352 HT---LLDYLSQFINAYPDQN-KFRWIWASILGHDSENGFPHSDKDFHKFLIKHREQ--LDNSFV 410

  Fly   397 ILMSDHGHRYNTLRRASTGYFEERMPMMFIYLPPWFRRKYPHLASNLGKNQNRLSSNYDVYMTLQ 461
            ..|.|||.|:..:|:...|..:...|.:.:.:|...|:. ..|.:.:.:|..::.:::|...|:.
 Worm   411 FFMGDHGLRFGNVRKTFVGTLDVSNPFLAVSIPKNLRQT-TGLLNVMRENAQKIQTHFDTRATML 474

  Fly   462 HLLQLDSKSVDEFPDNLRARQCKSCQSLFFELPFNRTCQMAGIEEKWCCCQ--PTETITNSPHVS 524
            .:|:..|.|.....|.|.....|....:..:....|.|:...|..::|.||  .|:..|.|....
 Worm   475 DILKYQSASNFTDLDPLIIPGEKGYSYIRTQPDILRNCRNMPIPMQYCICQFNKTQVSTKSETAK 539

  Fly   525 TIAEAIVQRMNEHLISHNLSDLCHNFTLDYVE---KADRKTILSNGLRPADKNEQVYIIVFE-TV 585
            .:.||:...:|..:.....:|.|....:|:|.   :.|:|.          |...:|..|.| |.
 Worm   540 GVGEAVALAVNNEIEEGKFTDKCVKMKVDHVVSLLQFDQKF----------KGSMLYTAVVEMTK 594

  Fly   586 PKNPIFEATVRWNSRTQRLLHFDVEEL---SRLTSYKNDANCINRKNAKKYCICKD 638
            |...:::|.|:      .|.:.:|:.|   .|...|.:.|.||..::.:.||.||:
 Worm   595 PSKAVYKANVK------ILENGEVKVLGMVERSNKYGSTAYCIGSEHHRPYCYCKN 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10730	NP_610021.3	DUF229	55..556	CDD:397236	112/528 (21%)
R03G8.3	NP_510174.3	DUF229	92..570	CDD:397236	112/525 (21%)