Protein Alignment CG10730 and F10C2.3

DIOPT Version :10

• Sequence 1: NP_610021.3
• Gene: CG10730 / 35291
• FlyBaseID: FBgn0032843
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_506015.2
• Gene: F10C2.3 / 179650
• WormBaseID: WBGene00008644
• Length: 604
• Species: Caenorhabditis elegans
• Alignment Length: 651
• Identity: 176/651 - (27%)
• Similarity: 277/651 - (42%)
• Gaps: 134/651 - (20%)

  Fly    35 SPVCQMPAVNPFTWD------TMSNFHRKTLRHCHNDSDMVTSEFDFETHQYRLHVHEHLAKPIM 93
            |..|.:|.::|  ||      .:.:..|.|...||:..  |..|..|......|.::.....
 Worm    47 SSKCVVPTLDP--WDQSILEYVLDDGSRPTQLACHDAK--VQPELTFLDENGVLQLNSTAVS--- 104

  Fly    94 NRKGNATLECEYQEISRDNSDQKPDNAYNQLRRRPIEQHQFVPNNTDYMITSC----YVRDVTK- 153
              :.:..:||:|:...:.:.|.:..| |::.    |..:..|...::::..||    :.|  ||
 Worm   105 --ESSLKVECQYRTYDKMDGDDEQLN-YSEW----ISFNMSVKIESEFVEVSCQRAWFPR--TKV 160

  Fly   154 ----HRELLQQDAISFIEDRLPKEKVKDFVKDESEVHKPSVLIMGLDSTSRINLRR-------AM 207
                |.:::.......:.|                  |.||:::.|||.|..|.||       .|
 Worm   161 YSNNHNQIIPISRSQPVSD------------------KSSVIVIVLDSVSHSNFRRTMNKTLDVM 207

  Fly   208 PSVYKFVRQPGWFEMQGYNKVGDNTFPNLLAALTG---DSEKGVGDYCDVTKPGCLDSLNFIWKR 269
            .|:|      |.|...|..|:|||:|.|.:....|   ::|.|       ...|..|..:.|||.
 Worm   208 HSLY------GSFIFDGMTKIGDNSFSNAVGFFAGKWWNTEFG-------DAHGYFDDHDLIWKH 259

  Fly   270 FKKANYTTAFAEDCSSISTFNYLKPGFVKQPTDYYLRPLLFAIEKQFKVTNDFGFAYCVGRHLSF 334
            :::..|.|.:|||....:.||||..||.|:|.|:|.||  :.:...:...:......|.|.|...
 Worm   260 YRENGYRTLYAEDYPGFNLFNYLSKGFKKKPVDHYFRP--YWLNVYWTYVHRRSRNLCYGNHRMH 322

  Fly   335 SYVWDFGQQFIDRFLGRSPMFGFLWSNSFTHDYYE----GATALDNLLWKYLKSFEESNLFQKSI 395
            :...::..||:.::..: |.|...|.....||:..    |...|.|.|.|:::..|.|.||
 Worm   323 NLQLNYLSQFVSKYKDQ-PKFAISWLTELGHDWLNQVRYGDEDLANFLKKHVEDLENSYLF---- 382

  Fly   396 VILMSDHGHRYNTLRRASTGYFEERMPMMFIYLPPWFRRKYPHLASNLGKNQNRLSSNYDVYMTL 460
              :|||||||::.:|:.|.|..|||:|...:.||... ||...|...:.||..:|:|.:|||.|.
 Worm   383 --IMSDHGHRFDNIRKTSIGRLEERLPFFSVSLPKKL-RKDSKLVDTVRKNSKKLTSFFDVYATF 444

  Fly   461 QHLLQLDSKSVDEFPDNLRARQCKSCQSLFFELPF-NRTCQMAGIEEKWCCCQPTE---TITNSP 521
            :|:|. :||.    ||.:|.      :|||  ||. :|.|:.|.|.|::|.|. ||   .::.:.
 Worm   445 RHILN-NSKQ----PDVMRG------ESLF--LPIKDRNCETAHIPEEFCVCD-TEVPLNVSANA 495

  Fly   522 HVSTIAEAIVQRMNEHLISHNLSDLCHNFTLDYVEKADRKTILSNGLRPADKNEQVYIIVFETVP 586
            .:.|:||...:.:|:.|..|   ..|....|        |.::|.. :..|..||.|....|..|
 Worm   496 QIRTMAEDFAKDINQRLDPH---PQCVQLYL--------KNVISVS-QVGDVKEQRYRFTIEVSP 548

  Fly   587 KNPIFEATVRWNSRTQRLLHFD--------VEELSRLTSYKNDANCINRKNAKKYCICKDSLSRP 643
            .|.||||          ||.:|        :.:::|:..|.|.:.|:..:..:|.|.|...|...
 Worm   549 SNAIFEA----------LLLYDPFESQTTVIGDINRINKYGNQSLCVQDQFLRKLCFCSTFLEAV 603

  Fly   644 S 644
            |
 Worm   604 S 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10730	NP_610021.3	DUF229	55..556	CDD:397236	145/527 (28%)
F10C2.3	NP_506015.2	ALP_like	182..451	CDD:293745	94/292 (32%)