DRSC/TRiP Functional Genomics Resources

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Protein Alignment vls and Wdr77

DIOPT Version :9

Sequence 1:NP_610019.2 Gene:vls / 35289 FlyBaseID:FBgn0003978 Length:367 Species:Drosophila melanogaster
Sequence 2:XP_038958345.1 Gene:Wdr77 / 310769 RGDID:1310479 Length:348 Species:Rattus norvegicus


Alignment Length:372 Identity:85/372 - (22%)
Similarity:141/372 - (37%) Gaps:67/372 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 PPPALELAGNLEYPNLNIADLNARLENLSPRLHDCW----DSIAINDHNHLALATNRREGRQWWG 78
            |||.:..|              ||..||.|....|.    ::........|.|..:...||.|.|
  Rat     6 PPPLVPPA--------------AREWNLPPNAPACMERQLEAARYRSDGSLLLGASSLSGRCWAG 56

  Fly    79 MLFGYGRDQMHHMSVDSANFKLQAEHTVNIVRYAEDDFLLVALGDTRLQAWSTYSKVRDSQSPYC 143
            .|: :.:|.....:....:..:|.|..|..:.:..|..:|||.....::.|..........|.:|
  Rat    57 SLW-FFKDPSAAPNEGFCSAGVQTEAGVADLTWVGDKGILVASDSGAVELWELDENETLIVSKFC 120

  Fly   144 LFLVGESSAHPTPISQLSVFKADPRTAVSGSADSTLNVWDLSGADMVSTYRSRSSHTDKLTGLAT 208
            .:      .|...:|.::|..:..: |||||.|..:.:|||:....:::||   :|..::|.:|.
  Rat   121 KY------EHDDIVSTVTVLSSGTQ-AVSGSKDFCIKIWDLAQQMSLNSYR---AHAGQVTCVAA 175

  Fly   209 PAASVDKFVTCDRGGCARLWDVRAAAPSST--------CLYADASHVLSFTSAAW-AAASELQGD 264
            .......|::|.......|||.|...|:|.        |   :||..|. ||.|| ...||:   
  Rat   176 SPHRETVFLSCSEDSRILLWDTRCPKPASQMGESELHGC---NASGYLP-TSLAWHPQQSEI--- 233

  Fly   265 NHIYLGDYDGKVHTLDIR--------VPRKLAETREYFDKGHVAQLLINGPHLAAMSNLPASVKV 321
              ...||.:|.|..:|.:        .......||..|....|       |.||::|.   ...:
  Rat   234 --FVFGDENGSVSLVDTKNASCTLSSAVHSQCVTRLVFSPHSV-------PFLASLSE---DCSL 286

  Fly   322 ANVQAGHEFIYTHQDTHSRLTDAVWT--DDSTLITIGHGRKMVTHAI 366
            |.:.:....::..:.....:.||.|:  :.|.|.|:|...:::.|.:
  Rat   287 AVLDSSFSEVFRSRAHRDFVRDATWSPLNHSLLTTVGWDHQVIHHVV 333

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
vlsNP_610019.2 WD40 106..>282 CDD:295369 48/184 (26%)
WD40 <134..>358 CDD:225201 58/242 (24%)
WD40 repeat 157..198 CDD:293791 13/40 (33%)
WD40 repeat 204..245 CDD:293791 11/48 (23%)
WD40 repeat 250..281 CDD:293791 10/31 (32%)
WD40 repeat 289..335 CDD:293791 9/45 (20%)
Wdr77XP_038958345.1 WD40 80..325 CDD:421866 65/273 (24%)
WD40 repeat 129..165 CDD:293791 13/39 (33%)
WD40 repeat 170..207 CDD:293791 10/36 (28%)
WD40 repeat 222..256 CDD:293791 11/38 (29%)
WD40 repeat 263..298 CDD:293791 9/44 (20%)
WD40 repeat 306..339 CDD:293791 8/28 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 68 1.000 Inparanoid score I5239
OMA 1 1.010 - - QHG50221
OrthoDB 1 1.010 - - D337178at33208
OrthoFinder 1 1.000 - - FOG0007197
OrthoInspector 1 1.000 - - oto98574
orthoMCL 1 0.900 - - OOG6_108117
Panther 1 1.100 - - LDO PTHR46853
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
87.980

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