Protein Alignment lok and MEK1

DIOPT Version :9

• Sequence 1: NP_477219.1
• Gene: lok / 35288
• FlyBaseID: FBgn0019686
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_014996.3
• Gene: MEK1 / 854533
• SGDID: S000005878
• Length: 497
• Species: Saccharomyces cerevisiae
• Alignment Length: 423
• Identity: 121/423 - (28%)
• Similarity: 194/423 - (45%)
• Gaps: 91/423 - (21%)

  Fly   102 KRANCELTNP---------------------VYIQDLSRNGTFVNNEKIGTNRMRILKNDDVISL 145
            |.....||||                     .|::|.|.|||::|...:..::..:||:.|||.|
Yeast    54 KECQLVLTNPSISSVHCVFWCVFFDEDSIPMFYVKDCSLNGTYLNGLLLKRDKTYLLKHCDVIEL 118

  Fly   146 SH--------PTYKAFVFKD-----LSPN--ESIGLPEEINKTYYVNRKLGSGAYGLVRLVYDTR 195
            |.        .|...|:..|     |.|.  :.:|...|:::....||.:|:|.:|.|.:.::::
Yeast   119 SQGSEENDIKKTRLVFMINDDLQSSLDPKLLDQMGFLREVDQWEITNRIVGNGTFGHVLITHNSK 183

  Fly   196 -----TC---QQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMKNLSHPCVVRM-HDIVDKPD 251
                 .|   :.:|:||:|..             |::...||:|:..|.||.:::: |...|:.:
Yeast   184 ERDEDVCYHPENYAVKIIKLK-------------PNKFDKEARILLRLDHPNIIKVYHTFCDRNN 235

  Fly   252 SVYMVLEFMRGGDLLNRIISNKLL---SEDISKLYFYQMCHAVKYLHDRGITHRDLKPDNVLLET 313
            .:|:..:.:.||||.:.:.....|   ||..|.|..:|:..|:.||||:.|.|||||.||:||.|
Yeast   236 HLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCT 300

  Fly   314 NDEETLLKVSDFGLSKFVQKDSV-MRTLCGTPLYVAPEVLITGGREA--------------YTKK 363
            .:..|.:.::|||::|.:..:.. |.|:.|||.|.||||.....|:|              |..|
Yeast   301 PEPCTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSK 365

  Fly   364 VDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQI----KKGRFAYGHPSWKSVSQRAKLLINQMLIV 424
            .|:|||||:....|:|..||   ||..:.:.|    |.|:..:....|..||..||..:..:|..
Yeast   366 CDLWSLGVITHIMLTGISPF---YGDGSERSIIQNAKIGKLNFKLKQWDIVSDNAKSFVKDLLQT 427

  Fly   425 DPERRPSIDDVLQSSWLRDAPMLQKAKRLMKLD 457
            |..:|.:....|:..|:        ||.|.:|:
Yeast   428 DVVKRLNSKQGLKHIWI--------AKHLSQLE 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lok	NP_477219.1	FHA	39..156	CDD:238017	21/82 (26%)
		STKc_Chk2	167..441	CDD:270986	91/304 (30%)
		S_TKc	174..441	CDD:214567	90/297 (30%)
MEK1	NP_014996.3	FHA	28..122	CDD:238017	19/67 (28%)
		STKc_CAMK	160..443	CDD:270687	90/298 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002433
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1619
TreeFam	0	0.000	Not matched by this tool.
	2	2.000