DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lok and CPK29

DIOPT Version :9

Sequence 1:	NP_477219.1	Gene:	lok / 35288	FlyBaseID:	FBgn0019686	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_974150.2	Gene:	CPK29 / 843936	AraportID:	AT1G76040	Length:	561	Species:	Arabidopsis thaliana

Alignment Length:	320	Identity:	100/320 - (31%)
Similarity:	167/320 - (52%)	Gaps:	27/320 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 EINKTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMK 233
            :::..|.::::||.|.:|:.....|....:::|.|.:.|..|...:      |.:.|..|..|::
plant   107 DLSALYDLHKELGRGQFGITYKCTDKSNGREYACKSISKRKLIRRK------DIEDVRREVMILQ 165

  Fly   234 NLS-HPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKYLHDR 297
            :|: .|.:|......:..|::::|:|...||:|.:|||.....||..:...|.|:.:.|...|..
plant   166 HLTGQPNIVEFRGAYEDKDNLHLVMELCSGGELFDRIIKKGSYSEKEAANIFRQIVNVVHVCHFM 230

  Fly   298 GITHRDLKPDNVLLETNDEETLLKVSDFGLSKFVQKDSVMRTLCGTPLYVAPEVLITGGREAYTK 362
            |:.||||||:|.||.:|:|::.:|.:|||||.|:::..|.|.:.|:..|||||||    ...|.|
plant   231 GVVHRDLKPENFLLVSNEEDSPIKATDFGLSVFIEEGKVYRDIVGSAYYVAPEVL----HRNYGK 291

  Fly   363 KVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKSVSQRAKLLINQMLIVDPE 427
            ::|:||.||:|:..|||..||..|......:.|.:|:.......|.::|:.||.||.:|||.||:
plant   292 EIDVWSAGVMLYILLSGVPPFWGETEKTIFEAILEGKLDLETSPWPTISESAKDLIRKMLIRDPK 356

  Fly   428 RRPSIDDVLQSSWLRDAPMLQK---------------AKRLMKLDGMEIEEENFLEPPTK 472
            :|.:..:.|:..|:.|..:..|               ..:|.|| .:::..||..|...|
plant   357 KRITAAEALEHPWMTDTKISDKPINSAVLVRMKQFRAMNKLKKL-ALKVIAENLSEEEIK 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lok	NP_477219.1	FHA	39..156	CDD:238017
		STKc_Chk2	167..441	CDD:270986	90/272 (33%)
		S_TKc	174..441	CDD:214567	90/267 (34%)
CPK29	NP_974150.2	S_TKc	112..370	CDD:214567	90/267 (34%)
		STKc_CAMK	112..369	CDD:270687	90/266 (34%)
		PTZ00184	405..548	CDD:185504	4/11 (36%)
		EFh	417..476	CDD:238008
		EFh	489..549	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910