DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lok and CDPK2

DIOPT Version :9

Sequence 1:	NP_477219.1	Gene:	lok / 35288	FlyBaseID:	FBgn0019686	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_174807.1	Gene:	CDPK2 / 840471	AraportID:	AT1G35670	Length:	495	Species:	Arabidopsis thaliana

Alignment Length:	312	Identity:	100/312 - (32%)
Similarity:	162/312 - (51%)	Gaps:	25/312 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 PNESIGLPEE---INKTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSD 221
            |:.:: ||.:   :...|.:.:|||.|.:|...|..:..|...:|.|.:.|..|      ....|
plant    10 PSNTV-LPYQTPRLRDHYLLGKKLGQGQFGTTYLCTEKSTSANYACKSIPKRKL------VCRED 67

  Fly   222 PDRVLNEAKIMKNLS-HPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFY 285
            .:.|..|.:||.:|| ||.|||:....:....|::|:|...||:|.:||:|....||..:.....
plant    68 YEDVWREIQIMHHLSEHPNVVRIKGTYEDSVFVHIVMEVCEGGELFDRIVSKGHFSEREAVKLIK 132

  Fly   286 QMCHAVKYLHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLSKFVQKDSVMRTLCGTPLYVAPE 350
            .:...|:..|..|:.||||||:|.|.::..::..||.:|||||.|.:....:..:.|:|.|||||
plant   133 TILGVVEACHSLGVMHRDLKPENFLFDSPKDDAKLKATDFGLSVFYKPGQYLYDVVGSPYYVAPE 197

  Fly   351 VLITGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKSVSQRAK 415
            ||    ::.|..::|:||.||:|:..|||..||..|..:...:||.:|:..:....|.::|:.||
plant   198 VL----KKCYGPEIDVWSAGVILYILLSGVPPFWAETESGIFRQILQGKLDFKSDPWPTISEAAK 258

  Fly   416 LLINQMLIVDPERRPSIDDVLQSSWLRD---AP-------MLQKAKRLMKLD 457
            .||.:||...|::|.|..:.|...|:.|   ||       :|.:.|:..:::
plant   259 DLIYKMLERSPKKRISAHEALCHPWIVDEQAAPDKPLDPAVLSRLKQFSQMN 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lok	NP_477219.1	FHA	39..156	CDD:238017
		STKc_Chk2	167..441	CDD:270986	92/277 (33%)
		S_TKc	174..441	CDD:214567	91/267 (34%)
CDPK2	NP_174807.1	STKc_CAMK	25..283	CDD:270687	91/267 (34%)
		Pkinase	26..284	CDD:278497	91/267 (34%)
		PTZ00184	320..462	CDD:185504
		EFh	332..391	CDD:238008
		EFh	404..463	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910