DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lok and CIPK18

DIOPT Version :9

Sequence 1:	NP_477219.1	Gene:	lok / 35288	FlyBaseID:	FBgn0019686	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_174217.1	Gene:	CIPK18 / 839797	AraportID:	AT1G29230	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	322	Identity:	102/322 - (31%)
Similarity:	174/322 - (54%)	Gaps:	30/322 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 SPNESIGLPEEINKTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKN--MLSGARPSTNFSD 221
            ||..:|     :...|.:.:.||.|.:..|.|..:.::..:.|:|::.|.  |.||.
plant    64 SPRNNI-----LMGKYELGKLLGHGTFAKVYLAQNIKSGDKVAIKVIDKEKIMKSGL-------- 115

  Fly   222 PDRVLNEAKIMKNLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQ 286
            ...:..|..|::.:.||.:|.:.:::.....:|.|:|::.||:|.|.:...: |.|:.::.||.|
plant   116 VAHIKREISILRRVRHPYIVHLFEVMATKSKIYFVMEYVGGGELFNTVAKGR-LPEETARRYFQQ 179

  Fly   287 MCHAVKYLHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLS---KFVQKDSVMRTLCGTPLYVA 348
            :..:|.:.|.||:.||||||:|:||   |.:..|||||||||   :.:::|.:..|.||||.|:|
plant   180 LISSVSFCHGRGVYHRDLKPENLLL---DNKGNLKVSDFGLSAVAEQLRQDGLCHTFCGTPAYIA 241

  Fly   349 PEVLITGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKSVSQR 413
            ||||...|.:|  .|.|:||.||:||..::|.:||.|:......::|.||.|..  |.|.| |..
plant   242 PEVLTRKGYDA--AKADVWSCGVILFVLMAGHIPFYDKNIMVMYKKIYKGEFRC--PRWFS-SDL 301

  Fly   414 AKLLINQMLIVDPERRPSIDDVLQSSWLRDAPMLQKAKRLMKLDGMEIEEENFLEPPTKRSR 475
            .:|| .::|..:|:.|.:|.:::::.|.:..  .:..|..::.|.:..|:|:..|..:...|
plant   302 VRLL-TRLLDTNPDTRITIPEIMKNRWFKKG--FKHVKFYIEDDKLCREDEDEEEEASSSGR 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lok	NP_477219.1	FHA	39..156	CDD:238017
		STKc_Chk2	167..441	CDD:270986	92/278 (33%)
		S_TKc	174..441	CDD:214567	92/271 (34%)
CIPK18	NP_174217.1	PKc_like	73..327	CDD:419665	92/271 (34%)
CIPK18	NP_174217.1	CIPK_C	388..499	CDD:213380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	200	1.000	Inparanoid score	I1313
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.050