DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lok and CPK17

DIOPT Version :9

Sequence 1:	NP_477219.1	Gene:	lok / 35288	FlyBaseID:	FBgn0019686	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_196779.1	Gene:	CPK17 / 831091	AraportID:	AT5G12180	Length:	528	Species:	Arabidopsis thaliana

Alignment Length:	353	Identity:	109/353 - (30%)
Similarity:	168/353 - (47%)	Gaps:	40/353 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 QDLSRNGTFVNNEKIGTNRMRILKNDDVISLSHPTYKAFV--FKDLSPNES-----------IGL 166
            :|.:.||..:.|....:|         ..:.:.||.:|.|  .|...|:..           :|.
plant     9 RDSADNGDALENGASASN---------AANSTGPTAEASVPQSKHAPPSPPPATKQGPIGPVLGR 64

  Fly   167 P-EEINKTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAK 230
            | |::..:|.:.::||.|.:|:..|.....|..|||.|.:.|..|      .|..|.:.|..|.:
plant    65 PMEDVKASYSLGKELGRGQFGVTHLCTQKATGHQFACKTIAKRKL------VNKEDIEDVRREVQ 123

  Fly   231 IMKNLS-HPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKYL 294
            ||.:|: .|.:|.:....:...||::|:|...||:|.:|||:....||..:......:...|...
plant   124 IMHHLTGQPNIVELKGAYEDKHSVHLVMELCAGGELFDRIIAKGHYSERAAASLLRTIVQIVHTC 188

  Fly   295 HDRGITHRDLKPDNVLLETNDEETLLKVSDFGLSKFVQKDSVMRTLCGTPLYVAPEVLITGGREA 359
            |..|:.||||||:|.||...||.:.||.:|||||.|.:...|.:.:.|:..|:|||||    :..
plant   189 HSMGVIHRDLKPENFLLLNKDENSPLKATDFGLSVFYKPGEVFKDIVGSAYYIAPEVL----KRK 249

  Fly   360 YTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKSVSQRAKLLINQMLIV 424
            |..:.||||:||:|:..|.|..||..|........|.:|...:....|.|:|.:||.|:.:||..
plant   250 YGPEADIWSIGVMLYILLCGVPPFWAESENGIFNAILRGHVDFSSDPWPSISPQAKDLVKKMLNS 314

  Fly   425 DPERRPSIDDVLQSSWLR------DAPM 446
            ||::|.:...||...|::      |.|:
plant   315 DPKQRLTAAQVLNHPWIKEDGEAPDVPL 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lok	NP_477219.1	FHA	39..156	CDD:238017	9/42 (21%)
		STKc_Chk2	167..441	CDD:270986	94/275 (34%)
		S_TKc	174..441	CDD:214567	92/267 (34%)
CPK17	NP_196779.1	STKc_CAMK	73..330	CDD:270687	92/266 (35%)
CPK17	NP_196779.1	PTZ00184	371..510	CDD:185504
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000