DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lok and CIPK2

DIOPT Version :9

Sequence 1:	NP_477219.1	Gene:	lok / 35288	FlyBaseID:	FBgn0019686	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_196324.1	Gene:	CIPK2 / 830598	AraportID:	AT5G07070	Length:	456	Species:	Arabidopsis thaliana

Alignment Length:	324	Identity:	115/324 - (35%)
Similarity:	172/324 - (53%)	Gaps:	39/324 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   167 PEEINKTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKI 231
            |..:.:.|.|.|.||.|.:..|.......|.:..|:|::.|:.:.....|      .::..|..:
plant     5 PSVLTERYEVGRLLGQGTFAKVYFGRSNHTNESVAIKMIDKDKVMRVGLS------QQIKREISV 63

  Fly   232 MKNLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKYLHD 296
            |:...||.||.:::::.....:|.|:|:.:||:|.|::...| |.||::..||||:..||.:.|.
plant    64 MRIAKHPNVVELYEVMATKSRIYFVIEYCKGGELFNKVAKGK-LKEDVAWKYFYQLISAVDFCHS 127

  Fly   297 RGITHRDLKPDNVLLETNDEETLLKVSDFGLSKFV---QKDSVMRTLCGTPLYVAPEVLITGGRE 358
            ||:.|||:||:|:||:.||.   |||||||||...   ::|.::.|.||||.||||||:...|.|
plant   128 RGVYHRDIKPENLLLDDNDN---LKVSDFGLSALADCKRQDGLLHTTCGTPAYVAPEVINRKGYE 189

  Fly   359 AYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKK-GRFAYGHPSWKSVSQRAKLLINQML 422
            .  .|.||||.|||||..|:|.|||.|   |...:..:| |:..:..|||  .:...|.|:.:||
plant   190 G--TKADIWSCGVVLFVLLAGYLPFHD---TNLMEMYRKIGKADFKCPSW--FAPEVKRLLCKML 247

  Fly   423 IVDPERRPSIDDVLQSSWLRDAPMLQKAKRLMKLDGMEIEE----------------ENFLEPP 470
            ..:.|.|.:|..:.:|||.|....| |.|::.|::..::.|                ||. |||
plant   248 DPNHETRITIAKIKESSWFRKGLHL-KQKKMEKMEKQQVREATNPMEAGGSGQNENGENH-EPP 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lok	NP_477219.1	FHA	39..156	CDD:238017
		STKc_Chk2	167..441	CDD:270986	103/277 (37%)
		S_TKc	174..441	CDD:214567	102/270 (38%)
CIPK2	NP_196324.1	PKc_like	11..265	CDD:419665	101/270 (37%)
CIPK2	NP_196324.1	CIPK_C	315..428	CDD:213380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000