DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lok and CRK29

DIOPT Version :9

Sequence 1:	NP_477219.1	Gene:	lok / 35288	FlyBaseID:	FBgn0019686	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_193872.2	Gene:	CRK29 / 827893	AraportID:	AT4G21410	Length:	679	Species:	Arabidopsis thaliana

Alignment Length:	248	Identity:	63/248 - (25%)
Similarity:	108/248 - (43%)	Gaps:	51/248 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   157 DLSPNESIGLPEEINKT----YYVNRKLGSGAYGLV-RLVYDTRTCQQFAMKIVKKNMLSGARPS 216
            :.|..||:.:..|..||    :....:||.|.:|.| :.|:...  |:.|:|.:..|...|
plant   336 EFSNTESLLVHFETLKTATDNFSSENELGRGGFGSVYKGVFPQG--QEIAVKRLSGNSGQG---- 394

  Fly   217 TNFSDPDRVLNEAKIMKNLSHPCVVRMHDIVDKPDSVYMVLEFMRGG------------DLLNRI 269
                 .:...||..::..|.|..:||:.....:.:...:|.||::..            .||:.:
plant   395 -----DNEFKNEILLLAKLQHRNLVRLIGFCIQGEERLLVYEFIKNASLDQFIFDTEKRQLLDWV 454

  Fly   270 ISNKLLSEDISKLYFYQMCHAVKYLHDRG---ITHRDLKPDNVLLETNDEETLLKVSDFGLSKFV 331
            :..|::.         .:...:.|||:..   |.|||||..|:||   |:|...|::||||:|..
plant   455 VRYKMIG---------GIARGLLYLHEDSRFRIIHRDLKASNILL---DQEMNPKIADFGLAKLF 507

  Fly   332 QKDSVM-----RTLCGTPLYVAPEVLITGGREAYTKKVDIWSLGVVLFTCLSG 379
            .....|     ..:.||..|:|||..:.|   .::.|.|::|.||::...::|
plant   508 DSGQTMTHRFTSRIAGTYGYMAPEYAMHG---QFSVKTDVFSFGVLVIEIITG 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lok	NP_477219.1	FHA	39..156	CDD:238017
		STKc_Chk2	167..441	CDD:270986	60/238 (25%)
		S_TKc	174..441	CDD:214567	57/227 (25%)
CRK29	NP_193872.2	Stress-antifung	38..130	CDD:366744
		Stress-antifung	159..245	CDD:366744
		STKc_IRAK	363..632	CDD:270968	57/221 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910