DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lok and SIP4

DIOPT Version :9

Sequence 1:	NP_477219.1	Gene:	lok / 35288	FlyBaseID:	FBgn0019686	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_180595.1	Gene:	SIP4 / 817586	AraportID:	AT2G30360	Length:	435	Species:	Arabidopsis thaliana

Alignment Length:	294	Identity:	114/294 - (38%)
Similarity:	175/294 - (59%)	Gaps:	22/294 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 YYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMKNLSHP 238
            |.:.:.||.||:..|....|.||.|..|:||:.|..|     .||.:..:.:..|..||:.||||
plant    21 YELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKL-----LTNPALANNIKREISIMRRLSHP 80

  Fly   239 CVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKYLHDRGITHRD 303
            .:|::|:::.....::..:||::||:|.|:|..:..||||:|:.||.|:..||.|.|.||:.|||
plant    81 NIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHARGVYHRD 145

  Fly   304 LKPDNVLLETNDEETLLKVSDFGLSKF---VQKDSVMRTLCGTPLYVAPEVLITGGREAYTKKVD 365
            |||:|:|:   ||...|||||||||..   ::.|.::.||||||.|||||:|...|.|.  .|||
plant   146 LKPENLLI---DENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYEG--AKVD 205

  Fly   366 IWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKSVSQRAKLLINQMLIVDPERRP 430
            :||.|:|||..::|.|||:|.......::|.||.:.:  |.|  :|...|..::::|.::||.|.
plant   206 VWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRF--PRW--MSPDLKRFVSRLLDINPETRI 266

  Fly   431 SIDDVLQSSWLRDAPMLQKAKRLMKLDGMEIEEE 464
            :||::|:..|     .::...:.:|....|||::
plant   267 TIDEILKDPW-----FVRGGFKQIKFHDDEIEDQ 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lok	NP_477219.1	FHA	39..156	CDD:238017
		STKc_Chk2	167..441	CDD:270986	109/269 (41%)
		S_TKc	174..441	CDD:214567	109/269 (41%)
SIP4	NP_180595.1	PKc_like	20..276	CDD:419665	109/268 (41%)
SIP4	NP_180595.1	CIPK_C	308..421	CDD:213380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	200	1.000	Inparanoid score	I1313
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101842
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.860