DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lok and sbk1

DIOPT Version :9

Sequence 1:	NP_477219.1	Gene:	lok / 35288	FlyBaseID:	FBgn0019686	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_688256.4	Gene:	sbk1 / 559792	ZFINID:	ZDB-GENE-091118-114	Length:	400	Species:	Danio rerio

Alignment Length:	278	Identity:	79/278 - (28%)
Similarity:	136/278 - (48%)	Gaps:	25/278 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 EINKTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMK 233
            |:.:.:.:...||.|.||.|.||.......:.|:|.|.||       .|....   .|.|..:..
Zfish    48 EVEQQFELISPLGKGTYGKVDLVVHRTQGTKLALKYVSKN-------KTKLRS---FLREYSLNA 102

  Fly   234 NLS-HPCVVRMHDIV-DKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKYLHD 296
            .|. .|.::::.::: :..||.....|:...|||.:.|.....|.|::.|....|:..|:.::|.
Zfish   103 ALGCSPFIIKVLNVLFETEDSYVFGQEYAPAGDLFDIIPPQAGLPEEMVKRCVQQLGLALDFMHS 167

  Fly   297 RGITHRDLKPDNVLLETNDEETLLKVSDFGLSKFVQKDSVMRTLCGTPLYVAPEVL---ITGGRE 358
            :.:.|||:||:|||| .:.|...:|::|.|:::  :..|.::.:.||..|.|.||.   ::.|..
Zfish   168 KSLVHRDVKPENVLL-FDRECRRVKLADLGMTR--RSGSRIKRISGTIPYTAAEVCQASVSEGII 229

  Fly   359 AYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPA----AQQIKKGRFAYGH-PS-WKSVSQRAKLL 417
            ..|.: |:|:.||:||..|:|..|:.......|    .|:.::|.|..|. || |:..|..|..:
Zfish   230 VATTQ-DVWAFGVLLFCMLTGNFPWEAALPNDAFFAEFQRWQRGAFPPGSVPSQWRRFSDDALRM 293

  Fly   418 INQMLIVDPERRPSIDDV 435
            ..::|.::||||..:.:|
Zfish   294 FGRLLALEPERRCGVKEV 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lok	NP_477219.1	FHA	39..156	CDD:238017
		STKc_Chk2	167..441	CDD:270986	79/278 (28%)
		S_TKc	174..441	CDD:214567	78/273 (29%)
sbk1	XP_688256.4	S_TKc	53..322	CDD:214567	78/273 (29%)
sbk1	XP_688256.4	STKc_SBK1	59..319	CDD:270889	78/267 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910