Protein Alignment lok and Lkb1

DIOPT Version :9

• Sequence 1: NP_477219.1
• Gene: lok / 35288
• FlyBaseID: FBgn0019686
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_001163606.1
• Gene: Lkb1 / 41673
• FlyBaseID: FBgn0038167
• Length: 567
• Species: Drosophila melanogaster
• Alignment Length: 449
• Identity: 117/449 - (26%)
• Similarity: 190/449 - (42%)
• Gaps: 94/449 - (20%)

  Fly    23 ESQPMEKIVWGRLYGKNIKIKSLGTSSKYRIIYTHSSFSVDLNNDEFT-------------AGRG 74
            |..|:|..:...|..||.                |...:.||::|.|.             ||.|
  Fly    61 EPDPVEDEMTVLLANKNF----------------HYDVASDLDDDAFVELKEDTAQADDAGAGVG 109

  Fly    75 EANDLILTLNDLPEKILTRISKVHF-IIKRANCELTNPVYIQDLSRNGTFVNNEKIGTNRMRILK 138
            ..|...|.|:|.|...:|.:..... .:.|...::.|..:                  ||   :.
  Fly   110 FYNPDELLLDDQPHPQVTWLDDDEIETLDRVTLDMGNMFF------------------NR---VD 153

  Fly   139 NDDVISLSHPTYKAFVFKDLSPNESIGLPEEINKTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMK 203
            :.|:|      |:       ...:||.:   :.| |.:...||.|:||.|:...::....:.|:|
  Fly   154 SQDII------YQ-------QKKKSIKM---VGK-YIMGDVLGEGSYGKVKEAMNSENLCRLAVK 201

  Fly   204 IVKKNMLSGARPSTNFSDPDRVLNEAKIMKNLSHPCVVRMHDIV--DKPDSVYMVLEFMRGGDLL 266
            |:.|..|   |...|  ....|..|..::|.|.|..||.:.|::  ::...:|:|:|:..||  |
  Fly   202 ILTKRKL---RRIPN--GEQNVTREIALLKQLKHRHVVELVDVLYNEEKQKMYLVMEYCVGG--L 259

  Fly   267 NRIIS---NKLLSEDISKLYFYQMCHAVKYLHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLS 328
            ..:|.   :|.:....:..||.|:...::|||...:.|:|:||.|:||..   :..||:||||::
  Fly   260 QEMIDYQPDKRMPLFQAHGYFKQLVDGLEYLHSCRVIHKDIKPGNLLLSL---DQTLKISDFGVA 321

  Fly   329 K---FVQKDSVMRTLCGTPLYVAPEVLITGGREAYTK-KVDIWSLGVVLFTCLSGTLPFSDEYGT 389
            :   ....|....|..|:|.:..||  |..|.|.:.. ||||||.||.|:...:|..||..:...
  Fly   322 EQLDLFAPDDTCTTGQGSPAFQPPE--IANGHETFAGFKVDIWSSGVTLYNLATGQYPFEGDNIY 384

  Fly   390 PAAQQIKKGRFAYGHPSW--KSVSQRAKLLINQMLIVDPERRPSIDDVLQSSWLRDAPM 446
            ...:.|  ||..:..|:|  :..:..|.|::. ||..||.:|.|:.::...:|.|.||:
  Fly   385 RLLENI--GRGQWEAPAWLYEMDADFANLILG-MLQADPSKRLSLQEIRHDTWFRSAPV 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lok	NP_477219.1	FHA	39..156	CDD:238017	22/130 (17%)
		STKc_Chk2	167..441	CDD:270986	84/284 (30%)
		S_TKc	174..441	CDD:214567	83/277 (30%)
Lkb1	NP_001163606.1	S_TKc	172..435	CDD:214567	83/277 (30%)
		STKc_LKB1	178..435	CDD:271021	82/271 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910