Protein Alignment lok and mek1

DIOPT Version :10

• Sequence 1: NP_477219.1
• Gene: lok / 35288
• FlyBaseID: FBgn0019686
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_594908.1
• Gene: mek1 / 2541604
• PomBaseID: SPAC14C4.03
• Length: 445
• Species: Schizosaccharomyces pombe
• Alignment Length: 379
• Identity: 118/379 - (31%)
• Similarity: 188/379 - (49%)
• Gaps: 48/379 - (12%)

  Fly   112 VYIQDLSRNGTFVNNEKIGTNRMRILKNDDVISLSHPTYKAFVFKDLSPN----ESIGLPEEINK 172
            ||.:|.|.||||:|:..||.....:|.:.|::.:.|.....|..|..:.|    |..|  |..|.
pombe    99 VYCEDQSSNGTFLNHRLIGKGNSVLLSDGDILDVRHCASFLFQQKYTTDNDFHHEYAG--ERFNI 161

  Fly   173 TYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMKNLSH 237
            |   .|.||.|.:..:.:..|..|..|:|.||:.|..:|..|   .|.|     :|..|::.|.|
pombe   162 T---QRLLGIGGFSRIYMAMDNNTGGQYACKIIDKKKISTKR---FFED-----HEMTILRKLDH 215

  Fly   238 PCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKYLHDRGITHR 302
            |.:::::...:.....::..|.:.||||.:.:.....:.|..:....:|:...:||||::.|.||
pombe   216 PNIIKVNMEYNSETQFFIFEEMVTGGDLFSYLTKLGTVPEVTTLFIMFQILQGLKYLHEQNIIHR 280

  Fly   303 DLKPDNVLLETNDEETLLKV--SDFGLSKFVQKDSVMRTLCGTPLYVAPEVLITGGR-------- 357
            |||.:|:|: .:..:|:.::  :|||:::.:||...:.|..|||.|.|||:....||
pombe   281 DLKLENILI-ASSSDTIFRIILTDFGVARCMQKGKRLSTFVGTPEYTAPEIQRLKGRSQVEKENS 344

  Fly   358 EAYTKKVDIWSLGVVLFTCLSGTLP-FSDEYGTPAAQQIKKGRFAYGHPSWKSVSQRAKLLINQM 421
            ..|.|:||:|||||::|..|||..| |:|        .:|:.:..:..|.|||||::||.||:.:
pombe   345 SGYGKEVDLWSLGVIMFLLLSGNSPSFAD--------GVKEKQVDFRDPVWKSVSRQAKDLISNL 401

  Fly   422 LIVDPERRPSIDDVLQSSWLRDAPMLQKAKRLMKLDGMEIEEENFLEPPTKRSR 475
            |..:|..|.::...|...|     ..:.:.||.||      .|..:..|.|.||
pombe   402 LKTNPPDRFTVKQCLSHPW-----FARHSSRLTKL------YETRILKPLKHSR 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lok	NP_477219.1	FHA_CHK2	32..158	CDD:438718	16/45 (36%)
		STKc_Chk2	167..441	CDD:270986	89/284 (31%)
mek1	NP_594908.1	FHA_MEK1-like	40..143	CDD:438722	15/43 (35%)
		STKc_CAMK	163..420	CDD:270687	86/273 (32%)