Protein Alignment lok and cmk-1

DIOPT Version :10

• Sequence 1: NP_477219.1
• Gene: lok / 35288
• FlyBaseID: FBgn0019686
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_500139.1
• Gene: cmk-1 / 176989
• WormBaseID: WBGene00000553
• Length: 348
• Species: Caenorhabditis elegans
• Alignment Length: 284
• Identity: 103/284 - (36%)
• Similarity: 151/284 - (53%)
• Gaps: 19/284 - (6%)

  Fly   159 SPNESIGLPEEINKTYYVNRKLGSGAYGLVRLVYDTRTC-QQFAMKIVKKNMLSGARPSTNFSDP 222
            :||.:      |.:.|.....||:||:..|.|....... |.:|:|.:.|..|.|...|..
 Worm    13 APNAT------IREKYDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCIDKKALKGKEESLE---- 67

  Fly   223 DRVLNEAKIMKNLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQM 287
                ||.|:::.|.|..:|::.|..|:...||:|:|.:.||:|.:||::....:|..:.....|:
 Worm    68 ----NEIKVLRKLRHNNIVQLFDTYDEKQFVYLVMELVTGGELFDRIVAKGSYTEQDASNLIRQV 128

  Fly   288 CHAVKYLHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLSKFVQKDSVMRTLCGTPLYVAPEVL 352
            ..||.::||.|:.||||||:|:|....||::.:.:||||||| .:...||.|.||||.|||||||
 Worm   129 LEAVGFMHDNGVVHRDLKPENLLYYNQDEDSKIMISDFGLSK-TEDSGVMATACGTPGYVAPEVL 192

  Fly   353 ITGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKSVSQRAKLL 417
               .::.|.|.||:||:||:.:..|.|..||.||.......||.||.:.:..|.|..:|..||..
 Worm   193 ---QQKPYGKAVDVWSIGVIAYILLCGYPPFYDESDANLFAQIIKGEYEFDAPYWDQISDSAKDF 254

  Fly   418 INQMLIVDPERRPSIDDVLQSSWL 441
            |..::..|||.|.:..|.|...|:
 Worm   255 ITHLMCCDPEARFTCQDALSHPWI 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lok	NP_477219.1	FHA_CHK2	32..158	CDD:438718
		STKc_Chk2	167..441	CDD:270986	100/274 (36%)
cmk-1	NP_500139.1	STKc_CaMKI	18..277	CDD:270985	100/270 (37%)