DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lok and AgaP_AGAP009034

DIOPT Version :9

Sequence 1:	NP_477219.1	Gene:	lok / 35288	FlyBaseID:	FBgn0019686	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_319785.4	Gene:	AgaP_AGAP009034 / 1279992	VectorBaseID:	AGAP009034	Length:	603	Species:	Anopheles gambiae

Alignment Length:	350	Identity:	113/350 - (32%)
Similarity:	176/350 - (50%)	Gaps:	53/350 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 NEKIGTNRMRILKNDDVISLSH------------PTYK--------AFVFKDLSP-NESI---GL 166
            ||::|.|...:...:.....:|            |..|        .||..|.|. |..|   .|
Mosquito   251 NERVGNNDFELEAEESKAIAAHRKTLRSSTTRTGPKPKMPVKSHNDTFVCVDESALNGGILPDSL 315

  Fly   167 PEEINKTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVL-NEAK 230
            |.|:...|.:...:|.|.:.:|..:.|.:...::|:||:.|:..:|         .|..| .|.:
Mosquito   316 PLELQAKYTLGSIVGDGNFAVVLKLKDKQNHTEYALKIIDKSKCAG---------KDHYLAAEIR 371

  Fly   231 IMKNLSHPCVVRM-HDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKYL 294
            :||.|:||.:::: ||| :...::|:|||.:|||||.:.|......||:.||:....:..|:.|:
Mosquito   372 VMKKLNHPYIIQLVHDI-ETMKNMYLVLELVRGGDLFDAITRVTRFSENQSKIMMKHLASAMAYM 435

  Fly   295 HDRGITHRDLKPDNVLLETNDE--ETLLKVSDFGLSKFVQKDSVMRTLCGTPLYVAPEVLITGGR 357
            |...|.|||:||:|:|:|.:.:  ..|||:.||||:..|.:.  :.::||||.|||||:|:..|
Mosquito   436 HSLSIVHRDIKPENLLVELDSDGNVVLLKLGDFGLACEVTEP--LLSICGTPTYVAPEILMESG- 497

  Fly   358 EAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQ------IKKGRFAYGHPSWKSVSQRAKL 416
              |..|:|:|:.|::|:..|.|..||.    :|..||      |..|.|.:..|.|.::....:.
Mosquito   498 --YGVKIDVWAAGIILYILLCGFPPFV----SPDNQQEQLFDAILNGYFDFPAPYWNNIGDSVRD 556

  Fly   417 LINQMLIVDPERRPSIDDVLQSSWL 441
            ||..||..|||.|.|.:|:|...||
Mosquito   557 LIINMLQSDPELRFSSEDILDHPWL 581

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lok	NP_477219.1	FHA	39..156	CDD:238017	9/49 (18%)
		STKc_Chk2	167..441	CDD:270986	97/283 (34%)
		S_TKc	174..441	CDD:214567	95/276 (34%)
AgaP_AGAP009034	XP_319785.4	DCX	45..134	CDD:214711
		UBQ	172..254	CDD:294102	2/2 (100%)
		PKc_like	322..580	CDD:304357	95/276 (34%)
		S_TKc	323..581	CDD:214567	95/276 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910