Protein Alignment lok and AgaP_AGAP004780

DIOPT Version :9

• Sequence 1: NP_477219.1
• Gene: lok / 35288
• FlyBaseID: FBgn0019686
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: XP_318036.4
• Gene: AgaP_AGAP004780 / 1278447
• VectorBaseID: AGAP004780
• Length: 1254
• Species: Anopheles gambiae
• Alignment Length: 620
• Identity: 142/620 - (22%)
• Similarity: 225/620 - (36%)
• Gaps: 198/620 - (31%)

  Fly     4 DTQGTQGTQSQASNIWTQVESQPMEKIVWGRLYGKNIKIKSLGTSSKYRIIYTHSSFSVDLNNDE 68
            |..|...|.:.:|     ..:|..|....|.|.|.|    |.|||       .||:.|:|.::
Mosquito   656 DASGVGATSADSS-----TATQDNENRQKGDLVGDN----SNGTS-------LHSASSLDASS-- 702

  Fly    69 FTAGRGEANDLILTLNDLPEKILTRISKVHFIIKRANCELTNPVYIQDLSRNGTFVNNEKIGTNR 133
            ....|.:|.|.:..:.|:|....|..:. |......|| |....:..::|...|   |..|.:::
Mosquito   703 ANGVREKAQDSMANVTDIPMPESTERAS-HSDQTDGNC-LAAAAHTSEISSTNT---NSGIASSK 762

  Fly   134 MRILKN-------------DDVISLSHPT------------YKAFV----------FKDLSPNES 163
            .:.|.|             .|:.....|.            .|..:          .:|||..|.
Mosquito   763 PKSLTNLPMPPGVNVAELEADLAQTPSPARPISPVAAVSAMKKGLLNLPMPPMVPGSEDLSGEED 827

  Fly   164 IGLP---------------------EEINKTYYVNRK---------------------------- 179
            ||.|                     ..:.:...:||:
Mosquito   828 IGSPLLPSNRDTIQNLTPSGQTAGKAPVARPRILNRRHSRNMTAPMSASGGKDWGERCVEVFDML 892

  Fly   180 --LGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMKNLSHPCVVR 242
              :|.|.||.|....|.:|.:..|:|.|:........|.|       .:.|.||::.|:|..:|.
Mosquito   893 EQIGEGTYGQVYKAKDQQTNELVALKKVRLEHEKEGFPIT-------AVREIKILRQLNHQNIVN 950

  Fly   243 MHDIV-DKPD---------SVYMVLEFMRGGDLLNRIISNKL-LSEDISKLYFYQMCHAVKYLHD 296
            :.:|| ||.|         |.|:|.|:| ..||:..:.|..: .:|..:.....|:...:.|.|.
Mosquito   951 LREIVTDKQDALEFRKDKGSFYLVFEYM-DHDLMGLLESGMVDFNEQNNASIMRQLLDGLNYCHK 1014

  Fly   297 RGITHRDLKPDNVLLETNDEETLLKVSDFGLSKFVQKDSVMRTLCG---TPLYVAPEVLITGGRE 358
            :...|||:|..|:|:....|   :|::||||::....|:..|....   |..|..||:|:  |.|
Mosquito  1015 KNFLHRDIKCSNILMNNRGE---VKLADFGLARLYNADNRERPYTNKVITLWYRPPELLL--GEE 1074

  Fly   359 AYTKKVDIWSLGVVLFTCLSGTL----PFSDEYGTPAAQQIKKGRFAYGHPS---WKSV------ 410
            .|...:|:||.|     |:.|.|    |.......||  |::......|.|:   |.:|
Mosquito  1075 RYGPAIDVWSCG-----CILGELFLKKPLFQANQEPA--QLEMISRLCGTPTPAVWPNVIKLPLF 1132

  Fly   411 -------SQRAKL-------------LINQMLIVDPERRPSIDDVLQSSWLRDA-------PML- 447
                   ..|.||             |::.||::||:||.:.:|.|:|:||::.       |.|
Mosquito  1133 HTLKSKKQYRRKLREDFVFMPMPSLDLLDSMLVLDPDRRITAEDALKSNWLKNVIPEQLPPPQLP 1197

  Fly   448 ----------QKAKRLMKLDGMEIEEENFLEPPTK 472
                      :|.:|.::    |.:|.:...||.|
Mosquito  1198 TWQDCHELWSKKRRRQLR----EQQESSLNLPPGK 1228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lok	NP_477219.1	FHA	39..156	CDD:238017	28/151 (19%)
		STKc_Chk2	167..441	CDD:270986	88/371 (24%)
		S_TKc	174..441	CDD:214567	87/343 (25%)
AgaP_AGAP004780	XP_318036.4	STKc_CDK12	881..1183	CDD:270847	85/321 (26%)
		S_TKc	889..1183	CDD:214567	85/313 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910