Protein Alignment lok and map3k10

DIOPT Version :9

• Sequence 1: NP_477219.1
• Gene: lok / 35288
• FlyBaseID: FBgn0019686
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: XP_002938858.3
• Gene: map3k10 / 100488058
• XenbaseID: XB-GENE-920944
• Length: 990
• Species: Xenopus tropicalis
• Alignment Length: 486
• Identity: 109/486 - (22%)
• Similarity: 195/486 - (40%)
• Gaps: 117/486 - (24%)

  Fly    10 GTQSQASNIWTQVESQPMEKIVWGRLYGKNIKIKSLGTSSK-YRIIYTHSSFSVDLNNDEFTAGR 73
            |.|.....:| |......|..||.       :::|.|.|:. :..::.:.:.:    .:|.|..|
 Frog     4 GPQKNEGFLW-QSSKDNKENGVWN-------EVQSYGVSNPLWMAVFDYEATA----EEELTLHR 56

  Fly    74 GEANDLILTLNDLPEKILTRISKVHFIIKRANCELTNPVYIQDLSRNGTFVNNEKIGTNRMRILK 138
            |:                                     .::.||::.|...:|...|.:::
 Frog    57 GD-------------------------------------LVEILSKDSTVSGDEGWWTGKIK--- 81

  Fly   139 NDDVISLSHPTYKAFVFKDLSPNESIGLP-----------EEINKTYYVNRKLGSGAYGLVRLVY 192
              |.:.:....|   |..|.......|.|           ||:|    :...:|.|.:|  ::..
 Frog    82 --DKVGIFPSNY---VVSDNKYTTLTGAPKQCPLPLEIEFEELN----LEEIIGVGGFG--KVYK 135

  Fly   193 DTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLN--------EAKIMKNLSHPCVVRMHDIVDK 249
            ......:.|:|.|:             .|||..:|        |||:...|.||.::.:..:..|
 Frog   136 GLWRGDEVAVKAVR-------------HDPDEDINVTAENVRQEAKLFCMLCHPNIIALKGVCLK 187

  Fly   250 PDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKYLHDRGIT---HRDLKPDNVL- 310
            |..:.:|:|:.|||. |:|.::.|.:...:...:..|:...:.|||:..|.   |||||..|:|
 Frog   188 PPHLCLVMEYARGGP-LHRALAGKKVPAHVLVNWAVQIARGMNYLHNEAIVPIIHRDLKSSNILI 251

  Fly   311 LETNDEETL----LKVSDFGLSKFVQKDSVMRTLCGTPLYVAPEVLITGGREAYTKKVDIWSLGV 371
            ||..:.:.|    ||::||||::..||.:.| :..||..::||||:   ....::|..|:||.||
 Frog   252 LEKVEHDDLFNKTLKITDFGLAREWQKTTKM-SAAGTYAWMAPEVI---RLSLFSKSSDVWSFGV 312

  Fly   372 VLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKSVSQRAKLLINQMLIVDPERRPSIDDVL 436
            :|:..|:|.:|:.:......|..:...:.....||  :..:....::......||..|||...:|
 Frog   313 LLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPS--TCPEPFVRILEACWDPDPHSRPSFSCIL 375

  Fly   437 -QSSWLRDAPMLQKAKRLMKLDGMEIEEENF 466
             |.:.:..:.|.|     |.|:.....:|::
 Frog   376 EQLTTIEQSAMFQ-----MPLESFHSLQEDW 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lok	NP_477219.1	FHA	39..156	CDD:238017	15/117 (13%)
		STKc_Chk2	167..441	CDD:270986	80/301 (27%)
		S_TKc	174..441	CDD:214567	76/283 (27%)
map3k10	XP_002938858.3	SH3_MLK1-3	37..94	CDD:212992	12/105 (11%)
		STKc_MLK2	124..381	CDD:271050	76/278 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910